期刊
ORGANIC LETTERS
卷 18, 期 21, 页码 5576-5579出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02815
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-
资金
- Deutsche Forschungsgemeinschaft (DFG)
AlBr3-mediated multicomponent 1,3-bifunctionalization of donor acceptor cyclopropanes using arenes and nitrosoarenes as coupling partners is presented. In the cascade, a C-C, a C-N, and a C-Br bond is formed. Reactions are easy to conduct and proceed under mild conditions. The gamma,gamma-disubstituted N-arylated alpha-amino esters obtained as products are readily further chemically modified rendering the method valuable.
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