☆ 4.8 Article

E- and Z-Selective Transfer Semihydrogenation of Alkynes Catalyzed by Standard Ruthenium Olefin Metathesis Catalysts

ORGANIC LETTERS (2016)

期刊

ORGANIC LETTERS

卷 18, 期 23, 页码 6196-6199

出版社

AMER CHEMICAL SOC

DOI: 10.1021/acs.orglett.6b03254

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Chemistry, Organic

资金

National Science Centre (Poland) [UMO-2013/09/B/ST5/03535]

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Protocol

Reagent

摘要

Selective transfer semihydrogenation of alkynes to yield alkenes was achieved with commercial first and second generation Hoveyda-Grubbs catalysts and formic acid as a hydrogen donor. This catalytic system is distinguished by its selectivity and compatibility with many functional groups (halogens, cyano, nitro, sulfide, alkenes). The metathetic activity of the ruthenium catalysts may be utilized in tandem sequences of olefin metathesis plus alkyne reduction.

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