Review
Biochemistry & Molecular Biology
Monika Kuczynska, Patrycja Jakubek, Agnieszka Bartoszek
Summary: The concept of oxidative stress and the search for antioxidant-based remedies has gained immense interest. However, commercial success of antioxidants has surpassed research on the exact redox mechanisms that control health and disease states. This review explores the redox network formed by ROS and cellular molecules, and its regulation of genomic and proteomic processes. It also highlights the concept of reductive stress, which is less well-established compared to oxidative stress.
Article
Biochemistry & Molecular Biology
Dmitry A. Guk, Karina R. Gibadullina, Roman O. Burlutskiy, Kirill G. Pavlov, Anna A. Moiseeva, Viktor A. Tafeenko, Konstantin A. Lyssenko, Erik R. Gandalipov, Alexander A. Shtil, Elena K. Beloglazkina
Summary: By synthesizing and characterizing a series of titanocene (IV) carboxylate complexes, this study optimized the synthetic methods and determined the substrate frames of each method, leading to higher yields of the target compounds. The relationship between the reduction potentials of titanocene (IV) and the structure of ligands, as well as their relative stability in redox processes, provides insights for the design and synthesis of new effective cytotoxic titanocene complexes. The synthesized carboxylate-containing derivatives of titanocene were found to be more resistant to hydrolysis than titanocene dichloride. Preliminary cytotoxicity tests on MCF7 and MCF7-10A cell lines showed that all the synthesized titanocene dicarboxylates had an IC50 value of >= 100 μM.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Halen Carbonel, Timothy D. Mikulski, Kahargyan Nugraha, James Johnston, Yichun Wang, Seth N. Brown
Summary: Optically active bis(aminophenols) are prepared and stereoselectively metalated to form palladium and platinum bis(iminosemiquinone) and oxoosmium bis(amidophenoxide) complexes.
DALTON TRANSACTIONS
(2023)
Review
Chemistry, Physical
Josef Bernauer, Jennifer Polker, Axel Jacobi von Wangelin
Summary: Recent studies have shown that alpha-diimine ligands (BIANs) exhibit great versatility and applicability in metal complexes, primarily due to their ability to undergo electronic manipulations and their significant contributions to the synthesis of small and functionalized organic molecules through metal-BIAN catalysts.
Article
Chemistry, Multidisciplinary
Ning Wang, Bin Feng, Peng Cui, Matthias Tamm, Yaofeng Chen
Summary: This study synthesized and characterized cerium(III) and cerium(IV) complexes supported by imidazolin-2-iminato ligands, and investigated their electrochemical properties.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Physical
Shuang Meng, He Zheng, Shuangfeng Jia, Lei Li, Ligong Zhao, Renhui Jiang, Longhui Ma, Weiwei Meng, Shizhou Pu, Dongshan Zhao, Jianbo Wang
Summary: The study using in situ TEM reveals the important impact of irradiation and size on the redox dynamics of iron nanoparticles. Strong electron beam irradiation may facilitate the reduction of Fe NPs, while weak irradiation may promote oxidation. Additionally, different sized Fe particles exhibit distinct pathways in the oxidation reactions, with a critical size estimated to be around 2.5 nm.
CHEMISTRY OF MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Wei Gong, Xinfa Chen, Wenqiang Zhang, Kent O. Kirlikovali, Bing Nan, Zhijie Chen, Rui Si, Yan Liu, Omar K. Farha, Yong Cui
Summary: In this study, single-site Rh species were successfully incorporated into a zirconium-based metal-organic framework using a sequential postsynthetic modification approach. The resulting Rh-monophosphorus material exhibited excellent catalytic performance in asymmetric hydrogenations, with higher activity than the homogeneous Rh-biphosphorus control.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Weigang Zhang, Mengjun Huang, Zhenlei Zou, Zhengguang Wu, Shengyang Ni, Lingyu Kong, Youxuan Zheng, Yi Wang, Yi Pan
Summary: Redox-active benzimidazolium sulfonamides have been developed as thiolating reagents for reductive C-S bond coupling. The IMDN-SO2R reagent provides a stable cationic precursor to generate highly active N-S intermediates, enabling successful cross-electrophilic coupling with various organic halides. The use of an electrophilic sulfur source has practical benefits such as broad substrate scope and excellent tolerance, while avoiding catalyst deactivation and unpleasant odors from thiols.
Review
Chemistry, Multidisciplinary
Gregory A. Dawson, Ethan H. Spielvogel, Tianning Diao
Summary: Nickel-catalyzed radical reactions are important for the synthesis of noncanonical peptides and carbohydrates, and have potential applications in chemical biology studies and drug discovery. The understanding of each step involving radicals, including initiation, propagation, termination, and the nuances of kinetics, origins of selectivity, and ligand effects, is crucial for the development of these reactions.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Simon B. H. Karnbrock, Manuel Alcarazo
Summary: The relevance of redox-active ligands in modern catalysis lies in their ability to easily deliver electrons and generate coordinated radicals, reducing reaction barriers and accessing multiple spin states. While this approach is well-established for metal central atoms, its application to p-block elements remains underdeveloped.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Inorganic & Nuclear
Puneet Singh Gahlaut, Kapil Yadav, Deepak Gautam, Barun Jana
Summary: Aluminum has advantages as a catalyst due to its easy availability, inexpensiveness, and non-toxicity, but the development of Al(I) molecular complexes supported by redox-active ligands is important for future applications of new catalysts.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Kelly L. Rue, Jeffrey R. McLachlan, Juliana A. Cazzaniga, Indranil Chakraborty, Christopher J. Dares, Raphael G. Raptis
Summary: Four new structurally similar dinuclear oxorhenium(V) complexes have been synthesized and characterized, showing little variation in spectroscopic features. All complexes exhibit a bent Re-O-Re core and distorted octahedral coordination geometry. A reversible one-electron electrochemical process is observed at approximately 0.84 V vs. Fc(+)/Fc in all four complexes, with a slight destabilization of the oxidized Re(VI) center when changing the terminal halide from chloride to bromide.
INORGANICA CHIMICA ACTA
(2021)
Review
Chemistry, Multidisciplinary
Hengwei Wang, Yu Pei, Keliang Wang, Yayu Zuo, Manhui Wei, Jianyin Xiong, Pengfei Zhang, Zhuo Chen, Nuo Shang, Daiyuan Zhong, Pucheng Pei
Summary: Rechargeable zinc-air batteries are considered a promising technology for energy conversion and storage, offering a cost-effective alternative to lithium-ion batteries. However, their practical application is hindered by slow reaction kinetics. Recent research has focused on using first-row transition metals as efficient and durable bifunctional electrocatalysts for the oxygen reduction and evolution reactions in zinc-air batteries. This review provides a comprehensive summary of the mechanisms, performance, and preparation strategies of these electrocatalysts in alkaline media and discusses future research trends.
Article
Chemistry, Multidisciplinary
Sebastian Haaf, Eliane Engels, Elisabeth Kaifer, Hans-Joerg Himmel
Summary: Novel redox-active hexaguanidine molecules with multiple redox states were synthesized and their electronic structure and charge delocalization were studied. Trinuclear high-spin metal complexes were also synthesized and their magnetic and redox properties were analyzed. The choice of oxidant can switch between metal- and ligand-centered oxidation reactions, leading to significant changes in magnetic or optical properties.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Environmental Sciences
Serhat Uzan
Summary: The existing reducing agents for methylene blue decolorization are soluble in water and the reduction process is carried out in a homogeneous redox reaction medium. However, these reducing agents often remain in the reaction medium after decolorization, leading to chemical pollution of textile wastewater. To address this issue, a water-insoluble redox active azo polymer was synthesized for heterogeneous reduction of methylene blue. The kinetic parameters of this redox reaction were investigated and compared with those of the azo polymer monomer (1,4-dihydroxybenzene).
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Inorganic & Nuclear
Daniel C. Ashley, Elena Jakubikova
INORGANIC CHEMISTRY
(2018)
Article
Chemistry, Physical
Daniel C. Ashley, Elena Jakubikova
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2019)
Article
Chemistry, Inorganic & Nuclear
Song Xu, Hyuk-Yong Kwon, Daniel C. Ashley, Chun-Hsing Chen, Elena Jakubikova, Jeremy M. Smith
INORGANIC CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Hosung Ki, Sungjun Park, Seunghwan Eom, Jain Gu, Siim Kim, Changwon Kim, Chi Woo Ahn, Minseo Choi, Sena Ahn, Doo-Sik Ahn, Jungkweon Choi, Mu-Hyun Baik, Hyotcherl Ihee
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Engineering, Environmental
Yinghao Wen, Ching-Hua Huang, Daniel C. Ashley, Dan Meyerstein, Dionysios D. Dionysiou, Virender K. Sharma, Xingmao Ma
Summary: This study reports the catalyst-free activation of peroxydisulfate (PDS) using visible light, which effectively degrades various organic pollutants. The formation of reactive species is different in the PDS visible light system with and without pollutants. The degradation of atrazine (ATZ) in the PDS visible light system involves both radical and nonradical processes, with O-1(2) playing an important role.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Juhee Kim, Junyue Wang, Daniel C. Ashley, Virender K. Sharma, Ching-Hua Huang
Summary: This study investigates the use of the chelating agent picolinic acid (PICA) to enhance the performance of the advanced oxidation process (AOP) involving the activation of peracetic acid (PAA) with iron species. It was found that the PAA-Fe(III)-PICA system degrades micropollutants much more rapidly at higher pH values, achieving almost complete removal of parent compounds within 10 minutes. PAA is a key oxidant in this process.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Junyue Wang, Juhee Kim, Daniel C. Ashley, Virender K. Sharma, Ching-Hua Huang
Summary: Ferrate(VI) and peracetic acid (PAA) are two oxidants that have been found to degrade micropollutants more efficiently when applied together. This study investigated the mechanisms behind this enhanced degradation and found that Fe(IV)/Fe(V) species were the main reactive agents, while organic radicals had little contribution. The study also revealed that PAA is not an activator for Ferrate(VI), but can enhance the oxidation capacity of Fe(IV)/Fe(V), leading to increased efficiency in wastewater treatment.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Juhee Kim, Junyue Wang, Daniel C. Ashley, Virender K. Sharma, Ching-Hua Huang
Summary: This study discovers that the biodegradable chelating ligand picolinic acid (PICA) can effectively mediate the activation of peracetic acid (PAA) by manganese (II), leading to accelerated degradation of micropollutants. The PAA-Mn(II)-PICA system is capable of rapidly removing various micropollutants in clean and wastewater matrices. High-valent manganese species (Mn(V)) is identified as the main reactive species contributing to the rapid degradation of micropollutants.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Inorganic & Nuclear
Hyuk-Yong Kwon, Daniel C. Ashley, Elena Jakubikova
Summary: This study explored the impact of halogenation on spin-state energetics and molecular structure in Fe(ii)-polypyridine complexes through density functional theory calculations. The results showed that halogenation has a clear and predictable influence on ligand rocking and spin-state energetics, which in turn affect the reorganization energies for spin-state changes. These findings help to interpret the experimentally measured excited-state lifetimes.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Physical
Richard Drew Marshburn, Daniel C. Ashley, Gregory M. Curtin, Nadia Sultana, Chang Liu, Nelson R. Vinueza, Elon A. Ison, Elena Jakubikova
Summary: Hybrid functionals with modest amounts of included Hartree-Fock exchange are most effective at matching experimentally determined lambda(max) in organic dyes, but the characterization of electronic excitations with charge-transfer character is highly sensitive to the chosen functional.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Correction
Chemistry, Multidisciplinary
Sarah E. Braley, Daniel C. Ashley, Krista M. Kulesa, Elena Jakubikova, Jeremy M. Smith
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Sarah E. Braley, Daniel C. Ashley, Elena Jakubikova, Jeremy M. Smith
CHEMICAL COMMUNICATIONS
(2020)
Meeting Abstract
Chemistry, Multidisciplinary
Jose Marc Madriaga, Hyuk-Yong Kwon, Daniel Ashley, Elena Jakubikova
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Article
Chemistry, Inorganic & Nuclear
Daniel Charles Ashley, Sriparna Mukherjee, Elena Jakubikova
DALTON TRANSACTIONS
(2019)
Meeting Abstract
Chemistry, Multidisciplinary
Daniel Ashley, Chang Liu, Jessica Gonzalez-Delgado, Elena Jakubikova
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)