标题
Cyclic peptide-based potent human SIRT6 inhibitors
作者
关键词
-
出版物
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 25, Pages 5928-5935
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-05-25
DOI
10.1039/c5ob02339d
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Simple N ε -thioacetyl-lysine-containing cyclic peptides exhibiting highly potent sirtuin inhibition
- (2016) Yajun Huang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Novel thiourea-based sirtuin inhibitory warheads
- (2015) Wenwen Zang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The ɛ-Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl-CoA Thioesters
- (2015) Zeljko Simic et al. CHEMBIOCHEM
- The chemical biology of sirtuins
- (2015) Bing Chen et al. CHEMICAL SOCIETY REVIEWS
- Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics
- (2015) Giovanna Sociali et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The role of mammalian sirtuins in cancer metabolism
- (2015) Carlos Sebastián et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Selective Sirt2 inhibition by ligand-induced rearrangement of the active site
- (2015) Tobias Rumpf et al. Nature Communications
- The Histone Deacetylase SIRT6: At the Crossroads Between Epigenetics, Metabolism and Disease
- (2015) Jean-Pierre Etchegaray et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies
- (2015) Yan-Bin Teng et al. Scientific Reports
- Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5
- (2014) Minjia Tan et al. Cell Metabolism
- Sirtuins, metabolism, and DNA repair
- (2014) Jee-Eun Choi et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Sirtuin inhibitors as anticancer agents
- (2014) Jing Hu et al. Future Medicinal Chemistry
- Discovery of Potent and Selective Sirtuin 2 (SIRT2) Inhibitors Using a Fragment-Based Approach
- (2014) Huaqing Cui et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Novel and Selective SIRT6 Inhibitors
- (2014) Marco Daniele Parenti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nonenzymatic Protein Acylation as a Carbon Stress Regulated by Sirtuin Deacylases
- (2014) Gregory R. Wagner et al. MOLECULAR CELL
- The growing landscape of lysine acetylation links metabolism and cell signalling
- (2014) Chunaram Choudhary et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Thiomyristoyl peptides as cell-permeable Sirt6 inhibitors
- (2014) Bin He et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
- (2014) E. Seto et al. Cold Spring Harbor Perspectives in Biology
- Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach
- (2014) Xiucong Bao et al. eLife
- Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins
- (2013) Jessica L. Feldman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3
- (2013) Jeremy S. Disch et al. JOURNAL OF MEDICINAL CHEMISTRY
- SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
- (2013) Hong Jiang et al. NATURE
- Sirtuins in neurodegenerative diseases: an update on potential mechanisms
- (2013) Sang-Won Min et al. Frontiers in Aging Neuroscience
- Discovery of Macrocyclic Peptides Armed with a Mechanism-Based Warhead: Isoform-Selective Inhibition of Human Deacetylase SIRT2
- (2012) Jumpei Morimoto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Sirtuin activators and inhibitors
- (2012) José M. Villalba et al. BIOFACTORS
- Mechanism-based Modulator Discovery for Sirtuin-catalyzed Deacetylation Reaction
- (2012) Weiping Zheng MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors
- (2012) Piia Kokkonen et al. ACS Medicinal Chemistry Letters
- A mechanism-based potent sirtuin inhibitor containing Nε-thiocarbamoyl-lysine (TuAcK)
- (2011) Brett M. Hirsch et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Medicinal Chemistry of Sirtuin Inhibitors
- (2011) L. Chen CURRENT MEDICINAL CHEMISTRY
- The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme
- (2011) Chao Peng et al. MOLECULAR & CELLULAR PROTEOMICS
- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
- (2011) J. Du et al. SCIENCE
- Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases
- (2010) Shin-ichiro Imai et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Nϵ-Thioacetyl-Lysine-Containing Tri-, Tetra-, and Pentapeptides as SIRT1 and SIRT2 Inhibitors
- (2009) Päivi H. Kiviranta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation
- (2009) Sebastian Greiss et al. MOLECULES AND CELLS
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
- (2008) Eriko Michishita et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now