Triggering apoptosis in cancer cells with an analogue of cribrostatin 6 that elevates intracellular ROS

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Organoytterbium Ate Complexes Extend the Value of Cyclobutenediones as Isoprene Equivalents

(2013) Emma Packard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Insights into Cyclobutenone Rearrangements: A Total Synthesis of the Natural ROS-Generating Anti-Cancer Agent Cribrostatin 6

(2011) Mubina Mohamed et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

Tandem electrocyclic ring opening/radical cyclization: application to the total synthesis of cribrostatin 6

(2011) Daniel Knueppel et al.   TETRAHEDRON

Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism

(2010) Mirth T. Hoyt et al.   INVESTIGATIONAL NEW DRUGS

Chemistry and Biology of Deoxynyboquinone, a Potent Inducer of Cancer Cell Death

(2010) Joseph S. Bair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Cribrostatin 6

(2009) Daniel Knueppel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Cribrostatin 6

(2008) Michael D. Markey et al.   JOURNAL OF ORGANIC CHEMISTRY