Synthesis and biological evaluation of triazole based uracil derivatives as novel DPP-4 inhibitors

Discovery of Novel P-Glycoprotein-Mediated Multidrug Resistance Inhibitors Bearing Triazole CoreviaClick Chemistry

(2014) Baomin Liu et al.   Chemical Biology & Drug Design

Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors

(2014) Bhumika D. Patel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Gliptins – do they increase cardiovascular risk or benefit?

(2014) Sheila A Doggrell et al.   Expert Opinion On Drug Safety

A review of gliptins for 2014

(2014) André J Scheen   EXPERT OPINION ON PHARMACOTHERAPY

A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site

(2013) Mika Nabeno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery of olmesartan hexetil: A new potential prodrug of olmesartan

(2013) Mohammed I. El-Gamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Diagnosis and Classification of Diabetes Mellitus

(2013)   DIABETES CARE

Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus

(2013) Benjamin M. Scirica et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design, Synthesis, ADME Properties, and Pharmacological Activities of β-Alanyl-D-histidine (D-Carnosine) Prodrugs with Improved Bioavailability

(2011) Marica Orioli et al.   ChemMedChem

Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor

(2011) Yasufumi Miyamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125

(2010) Yasufumi Miyamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV

(2010) Zhiyuan Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY