Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
出版年份 2016 全文链接
标题
Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
作者
关键词
-
出版物
ONCOGENE
Volume 36, Issue 19, Pages 2737-2749
出版商
Springer Nature
发表日期
2016-12-20
DOI
10.1038/onc.2016.427
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome
- (2016) Vaia Stavropoulou et al. CANCER CELL
- A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response
- (2016) George Sflomos et al. CANCER CELL
- Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
- (2016) Srinivas Malladi et al. CELL
- Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
- (2015) Neil E. Bhola et al. CANCER RESEARCH
- Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion
- (2015) Jean-Christophe Larsimont et al. Cell Stem Cell
- Overexpression of HMGA1 correlates with the malignant status and prognosis of breast cancer
- (2015) Ruixue Huang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity
- (2015) Alexandra Van Keymeulen et al. NATURE
- Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
- (2015) Xin Ye et al. NATURE
- PIK3CAH1047R induces multipotency and multi-lineage mammary tumours
- (2015) Shany Koren et al. NATURE
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- (2015) Devon A. Lawson et al. NATURE
- Epithelial to mesenchymal transition is associated with rapamycin resistance
- (2015) Ashley M. Holder et al. Oncotarget
- Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness
- (2015) Gorka Ruiz de Garibay et al. PLoS One
- Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
- (2015) Oncotarget
- The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells
- (2014) Gautam K Malhotra et al. BMC DEVELOPMENTAL BIOLOGY
- RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation
- (2014) M. Morales et al. EMBO Molecular Medicine
- MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis
- (2014) Chi-Hong Chao et al. JOURNAL OF CLINICAL INVESTIGATION
- PI3K and cancer: lessons, challenges and opportunities
- (2014) David A. Fruman et al. NATURE REVIEWS DRUG DISCOVERY
- Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
- (2013) Kevin J. Cheung et al. CELL
- Sox2 promotes tamoxifen resistance in breast cancer cells
- (2013) Marco Piva et al. EMBO Molecular Medicine
- Effect of visceral metastases on the efficacy and safety of everolimus in postmenopausal women with advanced breast cancer: Subgroup analysis from the BOLERO-2 study
- (2013) Mario Campone et al. EUROPEAN JOURNAL OF CANCER
- EVI1 splice variants modulate functional responses in ovarian cancer cells
- (2013) Punashi Dutta et al. Molecular Oncology
- EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation
- (2013) E. A. Bard-Chapeau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers
- (2013) D. Hagerstrand et al. Cancer Discovery
- mTOR Inhibitor RAD001 Promotes Metastasis in a Rat Model of Pancreatic Neuroendocrine Cancer
- (2012) S. E. Pool et al. CANCER RESEARCH
- RANK Induces Epithelial-Mesenchymal Transition and Stemness in Human Mammary Epithelial Cells and Promotes Tumorigenesis and Metastasis
- (2012) M. Palafox et al. CANCER RESEARCH
- Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State
- (2012) Wenjun Guo et al. CELL
- Systematic identification of genomic markers of drug sensitivity in cancer cells
- (2012) Mathew J. Garnett et al. NATURE
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- The translational landscape of mTOR signalling steers cancer initiation and metastasis
- (2012) Andrew C. Hsieh et al. NATURE
- eIF4F suppression in breast cancer affects maintenance and progression
- (2012) Z Nasr et al. ONCOGENE
- Negative Feedback and Adaptive Resistance to the Targeted Therapy of Cancer
- (2012) Sarat Chandarlapaty Cancer Discovery
- Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity
- (2011) Keisuke Kataoka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- The cancer stem cell: premises, promises and challenges
- (2011) Hans Clevers NATURE MEDICINE
- Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer
- (2011) José Baselga et al. NEW ENGLAND JOURNAL OF MEDICINE
- Transient mTOR Inhibition Facilitates Continuous Growth of Liver Tumors by Modulating the Maintenance of CD133+ Cell Populations
- (2011) Zhaojuan Yang et al. PLoS One
- A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs
- (2010) Jonghwan Kim et al. CELL
- Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
- (2010) Jianhui Ma et al. JOURNAL OF CLINICAL INVESTIGATION
- The PI3K Pathway As Drug Target in Human Cancer
- (2010) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Migrastatin analogues target fascin to block tumour metastasis
- (2010) Lin Chen et al. NATURE
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22
- (2010) J B Patel et al. ONCOGENE
- Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells
- (2008) David J. Wong et al. Cell Stem Cell
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More