Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer

Blocking immune checkpoints in prostate, kidney, and urothelial cancer: An overview

(2016) Angela K.B. Alme et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions

(2015) Ana-Rita Pedrosa et al.   Oncotarget

Correlation of Sprouty1 and Jagged1 With Aggressive Prostate Cancer Cells With Different Sensitivities to Androgen Deprivation

(2014) Naoki Terada et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Androgen Receptor Promotes the Oncogenic Function of Overexpressed Jagged1 in Prostate Cancer by Enhancing Cyclin B1 Expression via Akt Phosphorylation

(2014) Yongjiang Yu et al.   MOLECULAR CANCER RESEARCH

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee

(2013) M. Ittmann et al.   CANCER RESEARCH

Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

(2013) Michael G. Poulos et al.   Cell Reports

Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells

(2012) Josep Domingo-Domenech et al.   CANCER CELL

Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

(2012) D. J. Mulholland et al.   CANCER RESEARCH

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

(2012) Joseph M. Valdez et al.   Cell Stem Cell

The reactive stroma microenvironment and prostate cancer progression

(2012) David A Barron et al.   ENDOCRINE-RELATED CANCER

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells

(2011) Nilay Sethi et al.   CANCER CELL

Targeting the Notch Ligand Jagged1 in Both Tumor Cells and Stroma in Ovarian Cancer

(2011) A. D. Steg et al.   CLINICAL CANCER RESEARCH

Mechanism and Significance of cis-Inhibition in Notch Signalling

(2011) David del Álamo et al.   CURRENT BIOLOGY

Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism

(2011) Xinyu Wu et al.   DEVELOPMENTAL BIOLOGY

Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

(2011) Diana M Vallejo et al.   EMBO JOURNAL

Down regulation of CSL activity inhibits cell proliferation in prostate and breast cancer cells

(2011) Thomas Yong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

ADAM10 Overexpression Shifts Lympho- and Myelopoiesis by Dysregulating Site 2/Site 3 Cleavage Products of Notch

(2011) David R. Gibb et al.   JOURNAL OF IMMUNOLOGY

Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells

(2010) Zhiwei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TGF-β1 Induces an Age-Dependent Inflammation of Nerve Ganglia and Fibroplasia in the Prostate Gland Stroma of a Novel Transgenic Mouse

(2010) David A. Barron et al.   PLoS One

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Targeted Knockdown of Notch1 Inhibits Invasion of Human Prostate Cancer Cells Concomitant with Inhibition of Matrix Metalloproteinase-9 and Urokinase Plasminogen Activator

(2009) B. Bin Hafeez et al.   CLINICAL CANCER RESEARCH

A Role for Notch Signaling in Stromal Survival and Differentiation during Prostate Development

(2008) Brigid Orr et al.   ENDOCRINOLOGY