The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries

(2016) Valerie A. McCormack et al.   Cancer Epidemiology

STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis

(2015) Laura M. Jones et al.   CANCER RESEARCH

Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma

(2015) Yulong Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

SRSF3 and hnRNP H1 regulate a splicing hotspot ofHER2in breast cancer cells

(2015) Hannah Gautrey et al.   RNA Biology

Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab

(2014) L. Castagnoli et al.   CANCER RESEARCH

ERBB2 Deficiency Alters an E2F-1-Dependent Adaptive Stress Response and Leads to Cardiac Dysfunction

(2014) M.-C. Perry et al.   MOLECULAR AND CELLULAR BIOLOGY

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

(2014) Janna K Mouw et al.   NATURE MEDICINE

Targeting of preexisting and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1)

(2014) J Diessner et al.   Cell Death & Disease

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

(2014) Rekin's Janky et al.   PLoS Computational Biology

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice Variant

(2013) A. Alajati et al.   CANCER RESEARCH

Alternative expression analysis by RNA sequencing

(2010) Malachi Griffith et al.   NATURE METHODS

A pathway-based classification of human breast cancer

(2010) M. L. Gatza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Stat3-Dependent Transcription Regulatory Network Involved in Metastatic Progression

(2009) J. J. Ranger et al.   CANCER RESEARCH

Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression

(2009) R. L. Dillon et al.   CANCER RESEARCH

A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer

(2009) Theresa A. DiMeo et al.   CANCER RESEARCH

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

(2009) M. Yu et al.   GENES & DEVELOPMENT

c-Src Associates with ErbB2 through an Interaction between Catalytic Domains and Confers Enhanced Transforming Potential

(2009) R. Marcotte et al.   MOLECULAR AND CELLULAR BIOLOGY

An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance

(2009) D. Mitra et al.   MOLECULAR CANCER THERAPEUTICS

A Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks

(2009) Jeffrey T. Chang et al.   MOLECULAR CELL