MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
出版年份 2016 全文链接
标题
MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
作者
关键词
-
出版物
NUCLEIC ACIDS RESEARCH
Volume 44, Issue 12, Pages 5861-5871
出版商
Oxford University Press (OUP)
发表日期
2016-05-25
DOI
10.1093/nar/gkw468
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy
- (2015) Aurelio Reyes et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Primer removal during mammalian mitochondrial DNA replication
- (2015) Jay P. Uhler et al. DNA REPAIR
- TheSaccharomyces cerevisiaeDna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication
- (2015) Maryna Levikova et al. NUCLEIC ACIDS RESEARCH
- Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication
- (2015) J. Bradley Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies
- (2015) Ana Bratic et al. Nature Communications
- The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication
- (2015) Bertil Macao et al. Nature Communications
- Mitochondrial genome maintenance in health and disease
- (2014) William C. Copeland et al. DNA REPAIR
- Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease
- (2014) Thomas J. Nicholls et al. HUMAN MOLECULAR GENETICS
- In Vivo Occupancy of Mitochondrial Single-Stranded DNA Binding Protein Supports the Strand Displacement Mode of DNA Replication
- (2014) Javier Miralles Fusté et al. PLoS Genetics
- Replicating animal mitochondrial DNA
- (2013) Emily A. McKinney et al. GENETICS AND MOLECULAR BIOLOGY
- Exonuclease of human DNA polymerase gamma disengages its strand displacement function
- (2013) Quan He et al. MITOCHONDRION
- Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease
- (2013) Cornelia Kornblum et al. NATURE GENETICS
- Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels
- (2013) Roman J. Szczesny et al. NUCLEIC ACIDS RESEARCH
- A Cryptic Targeting Signal Creates a Mitochondrial FEN1 Isoform with Tailed R-Loop Binding Properties
- (2013) Lawrence Kazak et al. PLoS One
- Okazaki Fragment Metabolism
- (2013) L. Balakrishnan et al. Cold Spring Harbor Perspectives in Biology
- Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1
- (2012) Jason W. Gloor et al. NUCLEIC ACIDS RESEARCH
- Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells
- (2011) Heini Ruhanen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily
- (2011) Susan E. Tsutakawa et al. CELL
- Defects in mitochondrial DNA replication and human disease
- (2011) William C. Copeland CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Okazaki fragment maturation: nucleases take centre stage
- (2011) L. Zheng et al. Journal of Molecular Cell Biology
- Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States
- (2010) Elizabeth Cotner-Gohara et al. BIOCHEMISTRY
- The human mitochondrial replication fork in health and disease
- (2010) Sjoerd Wanrooij et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes
- (2010) Young-Hoon Kang et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication
- (2010) Javier Miralles Fusté et al. MOLECULAR CELL
- Pif1 Helicase Lengthens Some Okazaki Fragment Flaps Necessitating Dna2 Nuclease/Helicase Action in the Two-nuclease Processing Pathway
- (2009) Jason E. Pike et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA
- (2009) Laura J. Bailey et al. NUCLEIC ACIDS RESEARCH
- Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates
- (2009) Jason A. Stewart et al. NUCLEIC ACIDS RESEARCH
- Mitochondrial DNA replication and repair: all a flap
- (2009) Ian J. Holt TRENDS IN BIOCHEMICAL SCIENCES
- Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
- (2008) Mansour Akbari et al. DNA REPAIR
- Long Patch Base Excision Repair in Mammalian Mitochondrial Genomes
- (2008) Bartosz Szczesny et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria
- (2008) P. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- Human DNA2 Is a Mitochondrial Nuclease/Helicase for Efficient Processing of DNA Replication and Repair Intermediates
- (2008) Li Zheng et al. MOLECULAR CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started