Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity
出版年份 2016 全文链接
标题
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity
作者
关键词
-
出版物
NUCLEIC ACIDS RESEARCH
Volume 44, Issue 8, Pages 3892-3907
出版商
Oxford University Press (OUP)
发表日期
2016-03-05
DOI
10.1093/nar/gkw144
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular Chaperone Hsp90 Is a Therapeutic Target for Noroviruses
- (2015) Surender Vashist et al. JOURNAL OF VIROLOGY
- Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
- (2015) Xue-hai Liang et al. NUCLEIC ACIDS RESEARCH
- 2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF
- (2015) Wen Shen et al. NUCLEIC ACIDS RESEARCH
- Phosphorothioate oligonucleotides can displaceNEAT1RNA and form nuclear paraspeckle-like structures
- (2014) Wen Shen et al. NUCLEIC ACIDS RESEARCH
- TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells
- (2014) Xue-hai Liang et al. NUCLEIC ACIDS RESEARCH
- Antisense Oligonucleotides Capable of Promoting Specific Target mRNA Reduction via Competing RNase H1-Dependent and Independent Mechanisms
- (2014) Timothy A. Vickers et al. PLoS One
- Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells
- (2013) Xue-hai Liang et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- RNA helicase A is not required for RISC activity
- (2013) Xue-hai Liang et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs
- (2012) Pradeep S. Pallan et al. CHEMICAL COMMUNICATIONS
- Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides
- (2012) R. L. Juliano et al. JOURNAL OF DRUG TARGETING
- TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues—a comparative study of oligonucleotide length, design and chemistry
- (2012) Sue Murray et al. NUCLEIC ACIDS RESEARCH
- Hsp90 Interacts Specifically with Viral RNA and Differentially Regulates Replication Initiation of Bamboo mosaic virus and Associated Satellite RNA
- (2012) Ying Wen Huang et al. PLoS Pathogens
- The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones
- (2011) Jing Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides
- (2011) Rudolph L. Juliano et al. BIOCONJUGATE CHEMISTRY
- Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing
- (2011) Xue-hai Liang et al. NUCLEIC ACIDS RESEARCH
- Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes
- (2011) Erich Koller et al. NUCLEIC ACIDS RESEARCH
- RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
- (2010) C. Frank Bennett et al. Annual Review of Pharmacology and Toxicology
- HSP90 at the hub of protein homeostasis: emerging mechanistic insights
- (2010) Mikko Taipale et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RNA Interference: From Basic Research to Therapeutic Applications
- (2009) Jens Kurreck ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Antisense oligonucleotide pharmacokinetics and metabolism
- (2009) Richard S Geary Expert Opinion on Drug Metabolism & Toxicology
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