Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex

(2013) Konrad Bergen et al.   CHEMBIOCHEM

Kinetic Mechanism of Translocation and dNTP Binding in Individual DNA Polymerase Complexes

(2013) Kate R. Lieberman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ

(2013) Matthew Hogg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reaction Trajectory Revealed by a Joint Analysis of Protein Data Bank

(2013) Zhong Ren   PLoS One

A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site

(2013) Agata Jacewicz et al.   PLoS One

Reverse Engineering the Cooperative Machinery of Human Hemoglobin

(2013) Zhong Ren   PLoS One

Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA

(2012) Shuangluo Xia et al.   BIOCHEMISTRY

A Movie of RNA Polymerase II Transcription

(2012) Alan C.M. Cheung et al.   CELL

Direct Observation of Translocation in Individual DNA Polymerase Complexes

(2012) Joseph M. Dahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase

(2012) Shuangluo Xia et al.   PROTEIN SCIENCE

The Protein Data Bank at 40: Reflecting on the Past to Prepare for the Future

(2012) Helen M. Berman et al.   STRUCTURE

The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site

(2011) Karl E. Zahn et al.   BIOCHEMISTRY

Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase

(2011) Shuangluo Xia et al.   BIOCHEMISTRY

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

(2011) Eugene Y. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase

(2011) Karl E. Zahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex

(2011) Pierre Aller et al.   JOURNAL OF MOLECULAR BIOLOGY

Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures

(2011) Z. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,

(2010) Pierre Aller et al.   BIOCHEMISTRY

Reversal of a Mutator Activity by a Nearby Fidelity-Neutral Substitution in the RB69 DNA Polymerase Binding Pocket

(2010) Anna Trzemecka et al.   JOURNAL OF MOLECULAR BIOLOGY

RB69 DNA Polymerase Mutants with Expanded Nascent Base-Pair-Binding Pockets Are Highly Efficient but Have Reduced Base Selectivity

(2009) Hong Zhang et al.   BIOCHEMISTRY

DNA polymerase proofreading: Multiple roles maintain genome stability

(2009) Linda J. Reha-Krantz   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

(2009) Michael K Swan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

(2008) Scott D McCulloch et al.   CELL RESEARCH