TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function

Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer

(2015) Agnieszka Anna Rawłuszko-Wieczorek et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

TET1 is a tumor suppressor of hematopoietic malignancy

(2015) Luisa Cimmino et al.   NATURE IMMUNOLOGY

Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer

(2014) Chunping Du et al.   Gastric Cancer

SIN3A, Generally Regarded as a Transcriptional Repressor, Is Required for Induction of Gene Transcription by the Aryl Hydrocarbon Receptor

(2014) Parrisa Solaimani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation

(2014) Gary C. Hon et al.   MOLECULAR CELL

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

(2014) C. Jin et al.   NUCLEIC ACIDS RESEARCH

TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway

(2014) F Neri et al.   ONCOGENE

MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

(2014) Arun Gupta et al.   Cell Reports

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

(2013) Rachel Deplus et al.   EMBO JOURNAL

Sin3: Insight into its transcription regulatory functions

(2013) Rama Kadamb et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction

(2013) G. C. A. Taylor et al.   GENOME RESEARCH

Histone Deacetylase Regulation of ATM-Mediated DNA Damage Signaling

(2013) K. T. Thurn et al.   MOLECULAR CANCER THERAPEUTICS

Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells

(2013) Pietro Vella et al.   MOLECULAR CELL

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

(2013) K.-Y. Hsiao et al.   Journal of Molecular Cell Biology

Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells

(2013) Francesco Neri et al.   GENOME BIOLOGY

The MOF Chromobarrel Domain Controls Genome-wide H4K16 Acetylation and Spreading of the MSL Complex

(2012) Thomas Conrad et al.   DEVELOPMENTAL CELL

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

Tet1 controls meiosis by regulating meiotic gene expression

(2012) Shinpei Yamaguchi et al.   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

(2011) Zhiyong Mao et al.   CELL CYCLE

Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin

(2011) Lu Lu et al.   CELL RESEARCH

Tet proteins in the limelight

(2011) Nathalie Véron et al.   NATURE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

(2011) Hao Wu et al.   NATURE

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

(2010) G. G. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

MOF and H4 K16 Acetylation Play Important Roles in DNA Damage Repair by Modulating Recruitment of DNA Damage Repair Protein Mdc1

(2010) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation

(2009) Marnie E Gelbart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of TMS1/ASC Gene Activity

(2008) P. Kapoor-Vazirani et al.   CANCER RESEARCH