KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators

(2015) Eri Kawakami et al.   MECHANISMS OF DEVELOPMENT

Lentiviral vector-mediated insertional mutagenesis screen identifies genes that influence androgen independent prostate cancer progression and predict clinical outcome

(2015) Arun K. Nalla et al.   MOLECULAR CARCINOGENESIS

Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer

(2015) Hui Liu et al.   MOLECULAR CARCINOGENESIS

Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia

(2015) L M Heltemes-Harris et al.   ONCOGENE

CxxC-ZF Domain Is Needed for KDM2A to Demethylate Histone in rDNA Promoter in Response to Starvation

(2014) Yuji Tanaka et al.   CELL STRUCTURE AND FUNCTION

A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36

(2014) Zhongjun Cheng et al.   GENES & DEVELOPMENT

Transcriptional Repression of Histone Deacetylase 3 by the Histone Demethylase KDM2A Is Coupled to Tumorigenicity of Lung Cancer Cells

(2014) Shilpa S. Dhar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ensembl 2015

(2014) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

Histone demethylase KDM2A promotes tumor cell growth and migration in gastric cancer

(2014) Yufeng Huang et al.   TUMOR BIOLOGY

Beyond DNA: Programming and Inheritance of Parental Methylomes

(2013) Jamie A. Hackett et al.   CELL

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling

(2013) Klaus W. Wagner et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Visualization and targeted disruption of protein interactions in living cells

(2013) Henry D. Herce et al.   Nature Communications

Lysine-specific demethylase 2A (KDM2A) normalizes human embryonic stem cell derived keratinocytes

(2012) S. Iuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

(2011) David Frescas et al.   CELL CYCLE

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Recognition of CpG Island Chromatin by KDM2A Requires Direct and Specific Interaction with Linker DNA

(2011) J. C. Zhou et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation

(2010) Yuji Tanaka et al.   EMBO JOURNAL

CpG Islands Recruit a Histone H3 Lysine 36 Demethylase

(2010) Neil P. Blackledge et al.   MOLECULAR CELL

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

(2009) Tomasz Cierpicki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HP1: a functionally multifaceted protein

(2008) Laura Fanti et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT