Stable nuclear expression ofATP8andATP6genes rescues a mtDNA Complex Vnullmutant

Loss of mitochondrial DNA–encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly

(2016) Sze Chern Lim et al.   FASEB JOURNAL

Alteration of structure and function of ATP synthase and cytochromecoxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation

(2015) Kateřina Hejzlarová et al.   BIOCHEMICAL JOURNAL

Spectrum of combined respiratory chain defects

(2015) Johannes A. Mayr et al.   JOURNAL OF INHERITED METABOLIC DISEASE

MS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments

(2015) Matthew J. Rardin et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss

(2015) Hélène Cwerman-Thibault et al.   Molecular Therapy-Methods & Clinical Development

Capture of Somatic mtDNA Point Mutations with Severe Effects on Oxidative Phosphorylation in Synaptosome Cybrid Clones from Human Brain

(2014) Matthew McKenzie et al.   HUMAN MUTATION

Coenzyme Q10 as a therapy for mitochondrial disease

(2014) I.P. Hargreaves   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

LHON Gene Therapy Vector Prevents Visual Loss and Optic Neuropathy Induced by G11778A Mutant Mitochondrial DNA: Biodistribution and Toxicology Profile

(2014) R. Koilkonda et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Structural, Kinetic and Proteomic Characterization of Acetyl Phosphate-Dependent Bacterial Protein Acetylation

(2014) Misty L. Kuhn et al.   PLoS One

Differential targeting of VDAC3 mRNA isoforms influences mitochondria morphology

(2014) M. Michaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

(2014) Raeka S. Aiyar et al.   Nature Communications

Safety and Effects of the Vector for the Leber Hereditary Optic Neuropathy Gene Therapy Clinical Trial

(2014) Rajeshwari D. Koilkonda et al.   JAMA Ophthalmology

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

The mitochondrial protein import machinery has multiple connections to the respiratory chain

(2012) Bogusz Kulawiak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation

(2012) David U. Mick et al.   CELL

Nuclear Expression of a Mitochondrial DNA Gene: Mitochondrial Targeting of Allotopically Expressed Mutant ATP6 in Transgenic Mice

(2012) David A. Dunn et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline

(2012) Birgit Schilling et al.   MOLECULAR & CELLULAR PROTEOMICS

Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution

(2012) Maïlis Bietenhader et al.   PLoS Genetics

A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function

(2011) G. Gasparre et al.   CANCER RESEARCH

Induction of Rapid and Highly Efficient Expression of the Human ND4 Complex I Subunit in the Mouse Visual System by Self-complementary Adeno-Associated Virus

(2010) Rajeshwari D. Koilkonda   ARCHIVES OF OPHTHALMOLOGY

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Mitochondrial medicine: to a new era of gene therapy for mitochondrial DNA mutations

(2010) Hélène Cwerman-Thibault et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?

(2010) Ester Perales-Clemente et al.   NUCLEIC ACIDS RESEARCH

Infantile cardiomyopathy caused by a mutation in the overlapping region of mitochondrial ATPase 6 and 8 genes

(2009) S M Ware et al.   JOURNAL OF MEDICAL GENETICS

Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction

(2008) Sami Ellouze et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prevalence of mitochondrial DNA disease in adults

(2007) Andrew M. Schaefer et al.   ANNALS OF NEUROLOGY