Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA–DNA hybrids

Daily magnesium fluxes regulate cellular timekeeping and energy balance

(2016) Kevin A. Feeney et al.   NATURE

ViableRNaseH1knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

(2016) Walt F. Lima et al.   NUCLEIC ACIDS RESEARCH

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

Magnesium in Man: Implications for Health and Disease

(2015) Jeroen H. F. de Baaij et al.   PHYSIOLOGICAL REVIEWS

Regulation of ribosomal DNA amplification by the TOR pathway

(2015) Carmen V. Jack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Healthy aging: The ultimate preventative medicine

(2015) M. Kaeberlein et al.   SCIENCE

R-loops highlight the nucleus in ALS

(2015) Jayesh S Salvi et al.   Nucleus

R-loops highlight the nucleus in ALS

(2015) Jayesh S Salvi et al.   Nucleus

Non-coding RNA in neural function, disease, and aging

(2015) Kirk Szafranski   Frontiers in Genetics

The good and the bad of being connected: the integrons of aging

(2014) Andrew Dillin et al.   CURRENT OPINION IN CELL BIOLOGY

Roles for Pbp1 and Caloric Restriction in Genome and Lifespan Maintenance via Suppression of RNA-DNA Hybrids

(2014) Jayesh S. Salvi et al.   DEVELOPMENTAL CELL

Direct Binding of Ataxin-2 to Distinct Elements in 3′ UTRs Promotes mRNA Stability and Protein Expression

(2014) Moe Yokoshi et al.   MOLECULAR CELL

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2

(2014) Vaibhav Bhatia et al.   NATURE

Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA

(2014) Ruobo Zhou et al.   eLife

The fine line between lifespan extension and shortening in response to caloric restriction

(2014) Kirk Szafranski et al.   Nucleus

Cellular Senescence in Yeast Is Regulated by rDNA Noncoding Transcription

(2013) Kimiko Saka et al.   CURRENT BIOLOGY

The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability

(2013) J. M. Santos-Pereira et al.   GENES & DEVELOPMENT

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Determination of the biochemical properties of full-length human PIF1 ATPase

(2013) Yongqing Gu et al.   Prion

Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1

(2012) Jayesh S. Salvi et al.   AGING CELL

Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes

(2012) Amaya Alzu et al.   CELL

Cell biology of spinocerebellar ataxia

(2012) Harry T. Orr   JOURNAL OF CELL BIOLOGY

Perinuclear Cohibin Complexes Maintain Replicative Life Span via Roles at Distinct Silent Chromatin Domains

(2011) Janet N.Y. Chan et al.   DEVELOPMENTAL CELL

Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

(2011) Hannah E. Mischo et al.   MOLECULAR CELL

Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination

(2011) Konstantina Skourti-Stathaki et al.   MOLECULAR CELL

Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae

(2011) Jasmine S Smith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

(2010) Andrew C. Elden et al.   NATURE

The nuclear envelope in genome organization, expression and stability

(2010) Karim Mekhail et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Abundance of Ribosomal RNA Gene Copies Maintains Genome Integrity

(2010) S. Ide et al.   SCIENCE

A mother’s sacrifice: what is she keeping for herself?

(2008) Kiersten A Henderson et al.   CURRENT OPINION IN CELL BIOLOGY

Transcription Termination and RNA Degradation Contribute to Silencing of RNA Polymerase II Transcription within Heterochromatin

(2008) Lidia Vasiljeva et al.   MOLECULAR CELL

Role for perinuclear chromosome tethering in maintenance of genome stability

(2008) Karim Mekhail et al.   NATURE

The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain

(2008) Lidia Vasiljeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY