An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

(2014) Hao Wu et al.   CELL

Processive DNA Demethylation via DNA Deaminase-Induced Lesion Resolution

(2014) Don-Marc Franchini et al.   PLoS One

No Evidence for AID/MBD4-Coupled DNA Demethylation in Zebrafish Embryos

(2014) Nobuyoshi Shimoda et al.   PLoS One

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication

(2014) Toshihiro Shibutani et al.   Scientific Reports

Repair of naturally occurring mismatches can induce mutations in flanking DNA

(2014) Jia Chen et al.   eLife

DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

(2013) Chun-Chang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes

(2013) Ritu Kumar et al.   NATURE

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

Base Excision Repair

(2013) H. E. Krokan et al.   Cold Spring Harbor Perspectives in Biology

Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

(2013) Fátima Santos et al.   Epigenetics & Chromatin

5-Methylcytosine DNA Demethylation: More Than Losing a Methyl Group

(2012) Don-Marc Franchini et al.   Annual Review of Genetics

Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells

(2012) Javier Peña-Diaz et al.   MOLECULAR CELL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung−/−Msh2−/− mice

(2012) Kristin Kemmerich et al.   NUCLEIC ACIDS RESEARCH

Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA

(2012) Solange Moréra et al.   NUCLEIC ACIDS RESEARCH

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

(2011) Salvatore Cortellino et al.   CELL

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

(2011) Navjotsingh Pabla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity

(2011) Berit Doseth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

(2011) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hMsh2-hMsh6 Complex Acts in Concert with Monoubiquitinated PCNA and Pol η in Response to Oxidative DNA Damage in Human Cells

(2011) Anastasia Zlatanou et al.   MOLECULAR CELL

Demystifying DNA Demethylation

(2011) C. S. Nabel et al.   SCIENCE

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

(2010) Myunggon Ko et al.   NATURE

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic Reprogramming in Plant and Animal Development

(2010) Suhua Feng et al.   SCIENCE

Mutational spectra of human cancer

(2009) Gerd P. Pfeifer et al.   HUMAN GENETICS

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation

(2009) S. Schanz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

(2008) Kunal Rai et al.   CELL

Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain

(2008) Changxing Shao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proteasomal degradation restricts the nuclear lifespan of AID

(2008) Said Aoufouchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE