Defining the essential function of FBP/KSRP proteins:DrosophilaPsi interacts with the mediator complex to modulateMYCtranscription and tissue growth

Architecture of the RNA polymerase II–Mediator core initiation complex

(2015) C. Plaschka et al.   NATURE

The Mediator complex: a central integrator of transcription

(2015) Benjamin L. Allen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms

(2015) Gerardo Cárcamo-Oyarce et al.   Nature Communications

The Metazoan-Specific Mediator Subunit 26 (Med26) Is Essential for Viability and Is Found at both Active Genes and Pericentric Heterochromatin in Drosophila melanogaster

(2014) S. K. Marr et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting RNA polymerase I to treat MYC-driven cancer

(2014) G Poortinga et al.   ONCOGENE

Drosophila melanogaster Hox Transcription Factors Access the RNA Polymerase II Machinery through Direct Homeodomain Binding to a Conserved Motif of Mediator Subunit Med19

(2014) Muriel Boube et al.   PLoS Genetics

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

A structural perspective on Mediator function

(2012) Laurent Larivière et al.   CURRENT OPINION IN CELL BIOLOGY

Far upstream element binding protein 1: a commander of transcription, translation and beyond

(2012) J Zhang et al.   ONCOGENE

A Protein Complex Network of Drosophila melanogaster

(2011) K.G. Guruharsha et al.   CELL

Requirements for mediator complex subunits distinguish three classes of notch target genes at the Drosophila wing margin

(2011) Florence Janody et al.   DEVELOPMENTAL DYNAMICS

Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

(2010) N. C. Mitchell et al.   DEVELOPMENT

Molecular basis of FIR-mediated c-myc transcriptional control

(2010) Cyprian D Cukier et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activator-Mediator binding regulates Mediator-cofactor interactions

(2010) C. C. Ebmeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

Mediator Links Epigenetic Silencing of Neuronal Gene Expression with X-Linked Mental Retardation

(2008) Ning Ding et al.   MOLECULAR CELL

Mediator-Dependent Recruitment of TFIIH Modules in Preinitiation Complex

(2008) Cyril Esnault et al.   MOLECULAR CELL

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

The functional response of upstream DNA to dynamic supercoiling in vivo

(2008) Fedor Kouzine et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

(2008) Henri-Marc Bourbon   NUCLEIC ACIDS RESEARCH

Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein

(2008) L. R. Benjamin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13

(2008) I. Carrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA