Mammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early development

The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells

(2016) Ari Zukeran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The RNase PARN-1 Trims piRNA 3′ Ends to Promote Transcriptome Surveillance in C. elegans

(2016) Wen Tang et al.   CELL

Identification and Functional Analysis of the Pre-piRNA 3′ Trimmer in Silkworms

(2016) Natsuko Izumi et al.   CELL

The exonuclease Nibbler regulates age-associated traits and modulates piRNA length inDrosophila

(2015) Virzhiniya L. Feltzin et al.   AGING CELL

Long noncoding RNADANCRincreases stemness features of hepatocellular carcinoma by derepression ofCTNNB1

(2015) Sheng-xian Yuan et al.   HEPATOLOGY

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells

(2015) Xiaokan Zhang et al.   NUCLEIC ACIDS RESEARCH

Expression Atlas update—an integrated database of gene and protein expression in humans, animals and plants

(2015) Robert Petryszak et al.   NUCLEIC ACIDS RESEARCH

DNA demethylation by 5-aza-2′-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences

(2015) María-Paz Ramos et al.   Epigenetics & Chromatin

A Polyadenylation-Dependent 3′ End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA

(2015) Duy Nguyen et al.   Cell Reports

Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos

(2015) Elke F. Roovers et al.   Cell Reports

Self-association of poly(A)-specific ribonuclease (PARN) triggered by the R3H domain

(2014) Guang-Jun He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

(2014) Lan-Tao Gou et al.   CELL RESEARCH

Regulation of Pluripotency by RNA Binding Proteins

(2014) Julia Ye et al.   Cell Stem Cell

piRNAs: from biogenesis to function

(2014) E.-M. Weick et al.   DEVELOPMENT

Poly(A)-tail profiling reveals an embryonic switch in translational control

(2014) Alexander O. Subtelny et al.   NATURE

Deadenylation: enzymes, regulation, and functional implications

(2014) Yong-Bin Yan   Wiley Interdisciplinary Reviews-RNA

Poly(A)-specific ribonuclease (PARN): An allosterically regulated, processive and mRNA cap-interacting deadenylase

(2013) Anders Virtanen et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Argonaute and Triman Generate Dicer-Independent priRNAs and Mature siRNAs to Initiate Heterochromatin Formation

(2013) Mirela Marasovic et al.   MOLECULAR CELL

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Poly(A)-Specific Ribonuclease Mediates 3′-End Trimming of Argonaute2-Cleaved Precursor MicroRNAs

(2013) Mayuko Yoda et al.   Cell Reports

Biogeography of the ecosystems of the healthy human body

(2013) Yanjiao Zhou et al.   GENOME BIOLOGY

Modulation of Poly(A)-specific Ribonuclease (PARN): Current Knowledge and Perspectives

(2012) N. A.A. Balatsos et al.   CURRENT MEDICINAL CHEMISTRY

Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells

(2012) A. T. Neff et al.   GENOME RESEARCH

Translational control by changes in poly(A) tail length: recycling mRNAs

(2012) Laure Weill et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming

(2012) H. Berndt et al.   RNA

Uniting Germline and Stem Cells: The Function of Piwi Proteins and the piRNA Pathway in Diverse Organisms

(2011) Celina Juliano et al.   Annual Review of Genetics

Distinct expression patterns of the subunits of the CCR4–NOT deadenylase complex during neural development

(2011) Chuan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis

(2011) Ryan A. Hlady et al.   JOURNAL OF CLINICAL INVESTIGATION

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

(2010) Christel Rouget et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

The Many Pathways of RNA Degradation

(2009) Jonathan Houseley et al.   CELL

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members

(2009) V. V. Vagin et al.   GENES & DEVELOPMENT

Recognition of Adenosine Residues by the Active Site of Poly(A)-specific Ribonuclease

(2009) Niklas Henriksson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-Aza-2′-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1

(2009) Min Cui et al.   MEDICAL ONCOLOGY

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

(2009) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Promoter Methylation of Genes in and around the Candidate Lung Cancer Susceptibility Locus 6q23-25

(2008) M. Tessema et al.   CANCER RESEARCH

Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis

(2008) Nikolaos A. A. Balatsos et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Multifunctional deadenylase complexes diversify mRNA control

(2008) Aaron C. Goldstrohm et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY