Article
Chemistry, Analytical
Ju-Hong Jang, Sungsik Kim, Seul-Gi Kim, Jaemin Lee, Dong-Gwang Lee, Jieun Jang, Young-Su Jeong, Dong-Hyun Song, Jeong-Ki Min, Jong-Gil Park, Moo-Seung Lee, Baek-Soo Han, Jee-Soo Son, Jangwook Lee, Nam-Kyung Lee
Summary: The study successfully produced recombinant SEB using the baculovirus expression vector system and developed a reliable and sensitive immunodetection method for routine identification of SEB in various samples, including foods.
Article
Immunology
Elena Boero, Ana Rita Cruz, Werner Pansegrau, Cinzia Giovani, Suzan H. M. Rooijakkers, Kok P. M. van Kessel, Jos A. G. van Strijp, Fabio Bagnoli, Andrea G. O. Manetti
Summary: In this study, it was found that IgG3 antibodies in human sera effectively opsonized SpA-expressing Staphylococcus aureus, promoting Fcγ receptor-mediated interactions and phagocytosis. Furthermore, the capacity of SpA antibodies to induce phagocytosis depended on the specific epitope recognized by the IgGs on SpA molecules. These findings provide insights towards the identification of a correlate of protection against staphylococcal infections.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Li Li Tian, Chun Hong Li, Qi Chao Ye, Yuan Fang Li, Cheng Zhi Huang, Lei Zhan, Dong Mei Wang, Shu Jun Zhen
Summary: A centrifugal microfluidic chip-based strategy for point-of-care testing of Staphylococcal enterotoxin B (SEB) was proposed, utilizing an immune sandwich structure. The method allows for detection of SEB within 12 minutes, with good stability and a low limit of detection.
Article
Pharmacology & Pharmacy
Hasan Alghetaa, Amira Mohammed, Narendra Singh, Kiesha Wilson, Goushuai Cai, Nagireddy Putluri, Mitzi Nagarkatti, Prakash Nagarkatti
Summary: ARDS can be triggered by various insults, including bacterial and viral infections. Our study showed that Resveratrol treatment can prevent mortality in a murine model of ARDS induced by SEB. This prevention is achieved by attenuating inflammation and altering the metabolic reprogramming of SEB-activated immune cells, including the downregulation of mTOR expression and changes in energy metabolism. Furthermore, miR-100 may have therapeutic potential in the treatment of ARDS.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Food Science & Technology
Cecile Feraudet Tarisse, Celine Goulard-Huet, Yacine Nia, Karine Devilliers, Dominique Marce, Chloe Dambrune, Donatien Lefebvre, Jacques-Antoine Hennekinne, Stephanie Simon
Summary: Staphylococcal food poisoning, caused by staphylococcal enterotoxins, is a common foodborne disease. Researchers have developed monoclonal antibodies specific for different SEs and highly sensitive enzyme immunoassays for their detection, providing reliable tools for investigating SFP outbreaks.
Article
Chemistry, Physical
Gurudevaru Champaka, Kabali Senthilkumar, Ezhumalai David, Swaminathan Shanmugan, Nallasamy Palanisami
Summary: A monomeric zinc ferrocene carboxylate compound was synthesized and characterized, exhibiting a distorted tetrahedral geometry with broad emission band. The compound showed significant antibacterial activity, particularly against Proteus vulgaris bacteria.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Microbiology
Francisca J. Grill, Collin Jugler, Erin Kaleta, Qiang Chen, D. Mitchell Magee, Thomas E. Grys, Douglas F. Lake, Agostinho Carvalho, Joshua Fierer
Summary: At least half a million diagnostic tests for coccidioidomycosis are conducted annually in the southwestern and western regions of the United States. These tests require precise dilution of patient serum prior to testing. However, the FDA-approved enzyme immunoassays (EIAs) used for coccidioidomycosis diagnosis do not provide controls for the dilution step. This study evaluates the use of a humanized monoclonal antibody as a dilution control in these EIAs and demonstrates its effectiveness in ensuring accurate dilution and reliable results for diagnosis of coccidioidomycosis.
MICROBIOLOGY SPECTRUM
(2022)
Article
Food Science & Technology
Anna C. Hughes, Marina Kirkland, Wenxian Du, Reuven Rasooly, Bradley Hernlem, Christina Tam, Yuzhu Zhang, Xiaohua He
Summary: In this study, sixteen unique nanobodies were developed as specific and sensitive tools for detecting and neutralizing staphylococcal enterotoxin B (SEB). The nanobodies showed high specificity for SEB and could detect it with a lower limit of detection (LOD) of 50 pg/mL in PBS and 190 pg/mL in SEB-spiked milk. The thermal stability and long shelf-life of the nanobodies make them suitable for various applications, including the detection and management of SEB contamination in food products.
Article
Chemistry, Medicinal
Xiaohong Wang, Jianping Da, Yuanjian Liu
Summary: An electrochemical biosensor for staphylococcal enterotoxin B (SEB) detection has been designed based on the electrochemical interrogation of conformational changes, showing high sensitivity and accuracy.
Article
Chemistry, Physical
Laura Chronopoulou, Viviana Couto Sayalero, Hassan Rahimi, Aurelia Rughetti, Cleofe Palocci
Summary: Recent advances in nanotechnology have enabled the production of polymeric nanoparticles with specific morphologies and dimensions, allowing for tailored surfaces to manipulate characteristics for specific applications. Utilizing nanostructured polymeric carriers conjugated with anti-lipase monoclonal antibodies, an innovative approach for the immobilization of a commercial lipase from Candida rugosa was developed. Chemical conjugation of MoAbs on polymeric nanoparticles resulted in selective adsorption of CRL molecules, leading to a significant enhancement of enzymatic activity compared to the free enzyme.
Article
Chemistry, Applied
Hajar Jamali, Reza Teimuri-Mofrad
Summary: The synthesis of new ferrocene-based esters was conducted through alkylation of carboxylic acids with potassium carbonate as a base. 4-iodobutylferrocene was identified as the most effective initial reagent, leading to acceptable reaction yields without catalysts at room temperature. The cyclic voltammetry results demonstrated the potential electrochemical applications of the synthesized esters.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Analytical
Tomos E. Morgan, Craig Jakes, Hendrik-Jan Brouwer, Silvia Millan-Martin, Jean-Pierre Chervet, Ken Cook, Sara Carillo, Jonathan Bones
Summary: This article presents an online electrochemical reduction method for reducing disulfide bonds in antibodies during liquid chromatography mass spectrometry analysis, eliminating the need for chemical reducing agents. By optimizing parameters such as electrochemical potential, temperature, and solvent content, complete disulfide bond cleavage can be achieved efficiently.
Article
Chemistry, Analytical
Dharanivasan Gunasekaran, Yoram Gerchman, Sefi Vernick
Summary: The detection of microbial contamination in water is crucial for ensuring water quality. In this study, a new electrochemical method using bi-functional magnetic nanoparticles (MNP) conjugates was developed for rapid and highly sensitive detection of E. coli. This approach can also be applied for the detection of other bacteria and viruses.
Article
Chemistry, Analytical
Xiaolin Gao, Zhicong Sun, Xiaoyang Wang, Wanqi Zhang, Yue Wang, Jie Han, Xia Sun, Yemin Guo, Falan Li, Shicai Xu
Summary: A ratiometric electrochemical aptasensor was developed using Fc-labeled primers and GDY-MB nanocomposite for high-precision detection of KAN. The aptasensor exhibited strong stability, specificity, and successful detection of KAN in real milk samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Multidisciplinary Sciences
Cho Eun Kang, Seungeun Lee, Taeyoung Ahn, Dong Hye Seo, Byoung Joon Ko, Minkyu Jung, Jinu Lee, Joo Young Kim, Woo Taek Kim
Summary: Cancer therapy using immune checkpoint inhibitor antibodies has revolutionized cancer treatment. However, finding a way to eliminate these antibodies' effector function is crucial. In this study, researchers used glycoengineering to remove the cytotoxic effects of antibodies, while preserving their other functions.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Zihan Ma, Lishuang Wang, Tingting Chen, Guangning Wang
Summary: In this study, two kinds of 3D self-doped (N/O) lilac-based and coriander-based porous carbons with high performance have been prepared.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qin Wang, Yun-Fan Yan, Jiao-Lin Weng, Ying Huang, Fu Yang, Hao-Hui Xie, Fei Tan, Fa-Kun Zheng, Jian-Gang Xu
Summary: Balancing energy and mechanical sensitivities is a challenging issue in the field of energetic materials. This study constructed a 3D energetic metal-organic framework with nitrogen-rich ligand and NO3- anions. The framework demonstrated high stability, energy density, and excellent mechanical sensitivities, making it a potential insensitive energetic material.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Marrium Saeed, Urooj Kamran, Amina Khan, Md Irfanul Haque Siddiqui, Hasan Jamal, Haq Nawaz Bhatti
Summary: In this study, magnesium-aluminum layered double hydroxides (Mg-Al-LDH) were synthesized using an environmentally friendly hydrothermal technique for adsorbing the dye reactive green 5 (RG5). To improve the adsorption capability, composites were prepared by combining Mg-Al-LDH with low-cost Mangifera indica stone biomass (MISB). The results showed that the composites had high adsorption capacities for RG5 dye and could be regenerated.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Xuanlin Zhan, Xiaojie Li, Yunyan Zeng, Siyan Jiang, Chao Pan, Shiyu Pan, Jiaquan Huang, Heqian Zhang, Zhiwei Qin
Summary: This study reports on the potential prospects of natural products derived from the rhizosphere for the development of antibiotics and herbicides, as well as the advancements in cultivating a mutant strain that produces a substantial quantity of lydicamycins, a potent family for herbicide development.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jie Zhu, Jiangtao Yu, Linhua Zhu, Xiaoxiao Yu, Jixing Liu, Yanhong Chao, Jingzhou Yin, Peiwen Wu, Jian Liu, Wenshuai Zhu
Summary: This study successfully demonstrates the 3D printing of attapulgite monoliths and investigates the influence of thermal treatment on their properties. The thermal treated monoliths show superior catalytic performance at low temperatures.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yanzhu Ye, Yixiang Ye, Jiannan Cai, Zhongshui Li, Shen Lin
Summary: In this paper, a novel Pt/CoP/C photo-electro synergistic catalyst was successfully synthesized and its performance was investigated. The catalyst exhibited excellent photo-electro catalytic performance, with significantly higher hydrogen production compared to a commercial catalyst. The introduction of cobalt phosphide and the existence of Co3O4 were identified as key factors for enhancing the catalytic activity.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nurul Hidayah Abu Bakar, Wan Norfazilah Wan Ismail, Hartina Mohd Yusop, Noreen Farzuhana Mohd Zulkifli
Summary: Hydrophobic coatings inspired by the lotus effect have gained popularity for their ability to solve various problems. The sol-gel method, utilizing silica, alumina, and titania, is explored as an environmentally friendly approach to produce water-based hydrophobic coatings. This study focuses on producing water-based hydrophobic coatings for cotton and polyester fabrics using a one-step sol-gel method. The coated fabrics exhibited improved hydrophobic properties, altered surface morphologies, and lower air permeability compared to uncoated fabrics. TEOS-PDMS coating provides a promising approach for enhancing the hydrophobic and surface properties of cotton and polyester fabrics.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nikita Belko, Hanna Maltanava, Anatol Lugovski, Polina Shabunya, Sviatlana Fatykhava, Evgeny Bondarenko, Pavel Chulkin, Sergey Poznyak, Michael Samtsov
Summary: This study investigates the difference in electrochemical behavior between rhodamine B hydrazide and rhodamine B acylhydrazone, and finds that rhodamine B acylhydrazone exhibits higher reversibility in electrooxidation. These results can be applied for developing new sensors with desired electrochemical properties.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Showket Ahmad Bhat, Mohd Ikram
Summary: In this study, 0-3 particulate multiferroic composites were synthesized and characterized. The composites exhibited excellent ferroelectric and ferromagnetic properties, as well as high piezoelectric strain and magnetoelectric coupling effects.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Carla Gomes, Mariana Costa, Susana M. M. Lopes, Bernardo Albuquerque Nogueira, Rui Fausto, Jose A. Paixao, Teresa M. V. D. e Melo, Luisa M. D. R. S. Martins, Marta Pineiro
Summary: The development of sustainable processes requires the integration of green chemistry principles. In this study, a solvent-free synthesis method was developed to prepare new copper catalysts, which efficiently catalyze cycloaddition reactions under solvent-free mechanochemical conditions. Through this process, the principles of atom economy, reduction of solvents and auxiliaries, design for energy efficiency, and reduction of derivatives and catalysis are combined.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Zhihua Liu, Jinzhe Li, Jianguo Zhou
Summary: This study demonstrates the enhancement of photoelectrochemical activity of BiFeO3 photoelectrodes through ion modification, which increases visible light absorption and active area, leading to improved PEC water splitting performance.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yisheng Zhang, Wensong Li, Jing Li, Fang Li, Wei Xue, Xinqiang Zhao, Yanji Wang
Summary: Pt/C and SO42-/ZrO2 were used as catalysts for the synthesis of p-aminophenol through the catalytic transfer hydrogenation of nitrobenzene in water with formic acid as the hydrogen source. The optimal Pt loading for PAP selectivity was found to be 1 wt%. The presence of different valence states of Pt affected both the nitrobenzene hydrogenation and formic acid decomposition. Among different solid acid catalysts tested, SO42-/ZrO2 exhibited the highest catalytic activity for p-aminophenol formation. Under the optimized reaction conditions, the conversion of nitrobenzene reached 80.0%, with a selectivity of 47.6% for p-aminophenol.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Pradyota Kumar Behera, Papita Behera, Amlan Swain, Santosh Kumar Sahu, Ajeena Sahoo, Laxmidhar Rout
Summary: We have developed a simple and direct method for the synthesis of diaryl ether using an oxygen bridged bimetallic CuMoO4 nanocatalyst under mild reaction conditions. The catalyst exhibited tolerance towards a wide range of substrates with various functional groups. It is efficient and recyclable. This methodology allows easy access to nitrofen derivatives (herbicides) from unactivated 2,4-dichlorophenol, which are important for agriculture and pharmaceuticals.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yihua Fu, Yan Zhang, Changwei Hu, Zhishan Su
Summary: The mechanism of the reaction between CO2 and styrene oxide for cyclic carbonate was revealed using density functional theory calculations. The noncatalytic reaction occurred via a concerted mechanism, while in the presence of guanidine and tetrabutylammonium iodide (TBAI) co-catalysts, the epoxide ring-opening by nucleophilic attack of an iodide anion was predicted to be the rate-determining step. Guanidine acted as the H-bond donor to activate styrene oxide, facilitating the reaction with a lower activation barrier.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Saikat Khamarui, Sirshendu Ghosh
Summary: Copper nanorods (Cu-NRs) exhibit significant plasmonic behavior and can act as efficient catalysts in redox processes and coupling. A benign decarboxylative approach, utilizing localized surface plasmon resonance (LSPR) assisted catalysis with Cu-NRs, has been developed for the production of alkane analogues from alkyl carboxylic acids under visible light. The catalyst shows a broad substrate scope and high functional group tolerance, without the need for an external oxidant or proton source. A plausible mechanism for this recyclable nano-catalyst has also been proposed based on control experiments.
NEW JOURNAL OF CHEMISTRY
(2024)