Review
Medicine, General & Internal
Camille Heslot, Philippe Azouvi, Valerie Perdrieau, Aurelie Granger, Clemence Lefevre-Dognin, Melanie Cogne
Summary: This review summarizes the level of evidence concerning interventions for persistent post-concussion symptoms (PCS) after mild Traumatic Brain Injury (mTBI). Cognitive training, psycho-education, cognitive behavioral therapy, and graded return to physical activity showed some effectiveness in alleviating persistent PCS. Oculomotor rehabilitation, light therapy, and headache management using repetitive transcranial magnetic stimulation seem effective for somatic complaints and sleep disorders. However, there is limited evidence for the beneficial effect of Methylphenidate, and the preventive effect of early interventions remains debatable.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Kody R. Campbell, Robert J. Peterka, Peter C. Fino, Lucy Parrington, Jennifer L. Wilhelm, Natalie C. Pettigrew, Laurie A. King
Summary: This study examined the effectiveness of vestibular rehabilitation therapy with and without ABF in improving balance in people with chronic mTBI. Both groups showed improvements in PCSS and SOT scores, with the ABF group demonstrating better results in increasing motor activation and decreasing time delay. This suggests that incorporating motor activation factors in vestibular rehabilitation, possibly with ABF, may lead to more comprehensive assessment of recovery and improved outcomes.
FRONTIERS IN NEUROLOGY
(2022)
Article
Sport Sciences
Johna Register-Mihalik, Daniel D. Leeds, Emily Kroshus, Zachary Yukio Kerr, Kristen Knight, Christopher D'Lauro, Robert C. Lynall, Tanvir Ahmed, Yuta Hagiwara, Steven P. Broglio, Michael A. Mccrea, Thomas W. W. Mcallister, Julianne D. D. Schmidt
Summary: This study aimed to identify factors that can accurately classify previous concussion diagnosis status among collegiate student-athletes and service academy cadets. Machine learning techniques were used, and the results showed that both individual and institutional factors can achieve classification accuracy of over 50%. However, considering all factors, the average accuracy ranged from 56% to 65%. Similar performance was achieved when considering individual risk factors alone. In contrast, classifications using only institutional risk factors usually did not distinguish between diagnosed and undiagnosed concussions.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Review
Medicine, General & Internal
Hana Mala Rytter, Heidi J. Graff, Henriette K. Henriksen, Nicolai Aaen, Jan Hartvigsen, Morten Hoegh, Ivan Nisted, Erhard Trillingsgaard Naess-Schmidt, Lisbeth Lund Pedersen, Henrik Winther Schytz, Mille Moller Thastum, Bente Zerlang, Henriette Edemann Callesen
Summary: Persistent postconcussion symptoms (PPCS) lasting over 4 weeks are challenging for patients and clinicians, with uncertainty surrounding the effectiveness of nonpharmacological treatments. This study systematically assessed 7 nonpharmacological interventions for PPCS in adults and found weak evidence and recommendations for early information, physical exercise, vestibular rehabilitation, manual treatment, psychological treatment, and interdisciplinary rehabilitative treatment, while no relevant evidence was found for oculomotor treatment.
Article
Engineering, Biomedical
Dylan Powell, Alan Godfrey, Lucy Parrington, Kody R. Campbell, Laurie A. King, Sam Stuart
Summary: By evaluating the free-living gait quality of chronic mTBI patients and controls, it was found that there was no significant difference between the two groups, indicating that in this case, gait quality measurements may not be impaired.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2022)
Review
Neurosciences
Ekaterina Lunkova, Guido Guberman, Alain Ptito, Rajeet Singh Saluja
Summary: This review discusses various imaging methods for concussion, including fMRI, SWI, dMRI, and ASL, highlighting their benefits and drawbacks. A multimodal approach is recommended for a comprehensive understanding of mild traumatic brain injury mechanisms.
HUMAN BRAIN MAPPING
(2021)
Article
Clinical Neurology
Kelly Sarmiento, Jill Daugherty, Juliet Haarbauer-Krupa
Summary: While most healthcare providers are adhering to the guidelines on pediatric mild traumatic brain injury, there are still gaps in information regarding diagnosis and management. The study found that some providers are not using validated symptom scales for examination, assessing risk factors for prolonged recovery, and advising appropriate activities for patients.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2021)
Review
Sport Sciences
Caomhan Conaghan, Ed Daly, Alan J. Pearce, Doug A. King, Lisa Ryan
Summary: Educational interventions targeting concussion knowledge and attitudes are designed based on various frameworks, with expert opinion playing a significant role. While interventions following expert opinion tend to show short-term improvements in knowledge and attitudes, more research is needed to understand the long-term effects of these interventions.
JOURNAL OF SPORTS SCIENCES
(2021)
Review
Clinical Neurology
Shazia Malik, Omar Alnaji, Mahnoor Malik, Teresa Gambale, Forough Farrokhyar, Michel P. Rathbone
Summary: Mild traumatic brain injuries (mTBIs) result in a neuroinflammatory response characterized by perturbations in inflammatory cytokines. A systematic review and meta-analysis synthesized data on the levels of inflammatory cytokines in mTBI patients. The analysis included 26 studies and found that IL-6, IL-1RA, IFN-gamma, and MCP-1/CCL2 levels were elevated in mTBI patients compared to healthy controls. Furthermore, certain cytokines were associated with poor clinical outcomes following mTBI. This research emphasizes the need for standardized methodologies and provides guidance for future mTBI studies.
FRONTIERS IN NEUROLOGY
(2023)
Review
Clinical Neurology
Cristen Kaae, Kristin Cadigan, Katherine Lai, Jacqueline Theis
Summary: Individuals who have experienced a concussion/mild traumatic brain injury often suffer from vestibular and oculomotor dysfunction, resulting in various symptoms. The Vestibular/Ocular Motor Screening (VOMS) tool can be used to diagnose and refer patients for further evaluation and treatment. By identifying areas of impairment through proper assessment, targeted treatment programs can be designed to improve recovery.
NEUROREHABILITATION
(2022)
Review
Clinical Neurology
Emma Clark, Saurab Faruque, Cedric Mutebi, Newton V. Nagirimadugu, Alyssa Kim, Malavika Mahendran, Elaine Sullo, Rajendra Morey, Robert W. Turner
Summary: This systematic review aimed to synthesize recent literature on the relationship between mild traumatic brain injury (mTBI) and Alzheimer's disease and related dementias (ADRD). Of the eight relevant articles identified, four showed a significant relationship between mTBI and disease outcomes, highlighting the need for future research on this causal relationship. Future studies should standardize definitions and methodologies to produce more reliable and comprehensive results.
JOURNAL OF NEUROLOGY
(2022)
Article
Orthopedics
Jamie McAllister-Deitrick, Erica Beidler, Jessica Wallace, Morgan Anderson
Summary: There are significant differences in the knowledge of sport-related concussions among collegiate athletes, with female athletes scoring higher. Approximately one-quarter of athletes continue to play after suspecting a concussion. There are differences in reporting behaviors of suspected concussions between male and female athletes.
CLINICAL JOURNAL OF SPORT MEDICINE
(2022)
Review
Nutrition & Dietetics
Dean M. Cordingley, Stephen M. Cornish
Summary: This review examines the current literature on the efficacy of aerobic exercise following concussion and finds that participating in aerobic exercise below the point of symptom exacerbation is safe and does not delay time to medical clearance. Future research can further assess the impact of aerobic exercise on concussion and sex differences, as well as determine optimal exercise volume and intensity for treatment.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Review
Rehabilitation
Mille Nabsen Marwaa, Heidi Klakk Egebaek, Julie Dalgaard Guldager
Summary: This scoping review summarized the use of occupational and physiotherapy rehabilitation modalities in supporting interdisciplinary rehabilitation in adults with concussion. The study found that assessment, goal-setting, training, and social participation and discharge support were the main aspects addressed. Interventions were mainly delivered by physiotherapists or interdisciplinary teams, with a few studies including occupational therapists. However, there is still a need for more research on interventions for acute or subacute concussion patients.
JOURNAL OF REHABILITATION MEDICINE
(2023)
Review
Rehabilitation
Briar Coman, Dylan Powell, Julia Das, Lisa Graham, Rachel Mason, Mark Harrison, Glen Rae, Rodrigo Vitorio, Alan Godfrey, Samuel Stuart
Summary: Following mild traumatic brain injury (mTBI), early active rehabilitation may improve recovery time and symptom resolution. However, there is a lack of consensus regarding specific intervention protocols.
PHYSIOTHERAPY CANADA
(2023)
Article
Psychology, Clinical
Rune Raudeberg, Justin E. Karr, Grant L. Iverson, Asa Hammar
Summary: This study examined the frequency of invalid scores on the RBANS in patients with schizophrenia spectrum disorders and its association with symptoms of apathy. The results showed that the rate of invalid scores was similar to previous studies, and invalid scores on the BRIEF-A were uncommon.
CLINICAL NEUROPSYCHOLOGIST
(2023)
Review
Education & Educational Research
Joshua Altman, Cheree Padilla, Asim Merchant, Kirsty Freshwater, Sarah Weinsztok, James R. Clugston, Karen Fournier, Katherine M. Edenfield
Summary: This study aims to describe the clinical presentation and prevalence of COVID-19 in a collegiate population at the time of initial recognition and testing. The retrospective chart review of students tested for COVID-19 at the University of Florida Student Health Care Center showed that 8.4% of students tested positive. No significant differences were found in terms of travel history or known exposures between positive and negative students, but positive students experienced symptoms such as fatigue and congestion more commonly.
JOURNAL OF AMERICAN COLLEGE HEALTH
(2023)
Article
Psychology, Clinical
Ryan Van Patten, Grant L. Iverson
Summary: This study found that a history of multiple concussions is associated with subjective memory problems in older men, but to a lesser degree than fatigue, back or neck pain, and migraines.
CLINICAL NEUROPSYCHOLOGIST
(2023)
Article
Sport Sciences
Rachel Khinh Le, Justus Ortega, Sara P. Chrisman, Anthony P. Kontos, Thomas A. Buckley, Thomas W. Kaminski, Briana P. Meyer, James R. Clugston, Joshua T. Goldman, Thomas McAllister, Michael McCrea, Steven P. Broglio, Julianne D. Schmidt
Summary: The K-D test showed high diagnostic accuracy at 0 to 6 hours and 24 to 48 hours postconcussion, but declined at later time points. The use of an iPad for the test yielded better results compared to the spiral-bound card system.
JOURNAL OF ATHLETIC TRAINING
(2023)
Article
Clinical Neurology
Nathan E. Cook, Charles E. Gaudet, Ross Zafonte, Paul D. Berkner, Grant L. Iverson
Summary: Adolescents with ADHD may experience more severe acute effects following concussion, including cognitive impairment and worsened symptoms. However, there were no significant differences in the magnitudes of changes in overall symptom reporting compared to youth without ADHD. Further research is needed to determine whether these differences are associated with recovery time in youth with ADHD.
CHILD NEUROPSYCHOLOGY
(2023)
Article
Emergency Medicine
Tom N. Pham, Andrea K. Morrison, Michael S. Menard, Deborah Martinez, Danny G. Thomas
Summary: This study compared the effectiveness of comic-based with text-based concussion discharge instructions on improving caregiver knowledge. It also examined the role of social determinants of health on comprehension instructions. The results showed that caregivers with comic-based content were more likely to accurately recall overall discharge instructions, particularly physical rest and activity restrictions.
JOURNAL OF EMERGENCY NURSING
(2023)
Article
Sport Sciences
Allyssa K. Memmini, Michael J. Popovich, Kristen H. Schuyten, Stanley A. Herring, Katie L. Scott, James R. Clugston, Meeryo C. Choe, Christopher M. Bailey, M. Alison Brooks, Scott A. Anderson, Michael A. McCrea, Anthony P. Kontos, Jessica S. Wallace, Johna K. Register Mihalik, Tricia M. Kasamatsu, Tamara Valovich McLeod, Michelle L. Weber Rawlins, Traci R. Snedden, Matthew Kaplan, Briana Akani, La'Joya C. L. Orr, Rebecca E. Hasson, Sami F. Rifat, Steven P. Broglio
Summary: This study developed academic recommendations for university students during their recovery from sport-related concussions, addressing the unique challenges they face when returning to the classroom. The findings provide guidelines for seeking medical care and approaching instructors for academic support, and suggest a multidisciplinary approach between medical and academic stakeholders.
Article
Sport Sciences
Terese L. Chmielewski, Shuhei Suzuki, Dominique Dubose, Daniel C. Herman, James R. Clugston, MaryBeth Horodyski
Summary: In athletes with sport-related concussion (SRC), there is only a minimal decrease in quadriceps and hamstring strength at the time of return to play compared with controls, and this difference diminishes over a 30-day period.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Article
Neurosciences
Roisin Leahy, Enda Whyte, Keith D. Rochfort, Anthony P. Kontos, Michael W. Collins, Siobhan O'Connor
Summary: This study examines the factors associated with concussion management behavior in adult Ladies Gaelic Football players. The findings suggest that being diagnosed with a concussion greatly influences the subacute management behavior. It is recommended to improve access to medical personnel and introduce comprehensive concussion education to ensure proper medical care for players.
Editorial Material
Sport Sciences
Gavin A. Davis, Jon Patricios, Kathryn J. Schneider, Grant L. Iverson, Noah D. Silverberg
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Review
Sport Sciences
Grant L. Iverson, Rudolph J. Castellani, J. David Cassidy, Geoff M. Schneider, Kathryn J. Schneider, Ruben J. Echemendia, Julian E. Bailes, K. Alix Hayden, Inga K. Koerte, Geoffrey T. Manley, Michael McNamee, Jon S. Patricios, Charles H. Tator, Robert C. Cantu, Jiri Dvorak
Summary: There is concern about the potential adverse effects of sport-related concussion or repetitive head impacts on the later-in-life brain health of former athletes. A systematic review of the available studies suggests that exposure to repetitive head impacts is not associated with an increased risk of mental health problems or neurological diseases in former amateur athletes. However, some studies indicate a possible increased risk of neurological disorders, such as ALS and dementia, in former professional athletes, but these findings need to be confirmed in higher quality studies.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Multidisciplinary Sciences
Bhavna W. Singichetti, Stephen M. Marshall, Katherine L. Breedlove, Kenneth A. Cameron, Michael W. McCrea, Thomas P. McAllister, Steven Broglio
Summary: This study examines institutional risk factors and variability in concussion rates in sports-related concussion (SRC) using data from 53,822 athletes seasons. Results show that the majority of concussion variability is within schools, with school-level risk factors accounting for a third of the variability. Understanding school-level determinants of concussion risk is important for implementing individual-level interventions.
Article
Sport Sciences
Allyssa Memmini, Kelly Mosesso, Susan Perkins, Benjamin Brett, Paul Pasquina, Thomas McAllister, Michael McCrea, Steven Broglio
Summary: This study compares premorbid factors and post-injury characteristics among a large cohort of collegiate student athletes, finding that race and gender have an impact on the risk of sport-related concussions. There are also differences in post-injury characteristics based on contact level and gender.
Article
Orthopedics
Shane M. Miller, Tamara C. Valovich McLeod, Tracy L. Zaslow, Julie C. Wilson, Christina L. Master, Traci R. Snedden, Mark E. Halstead, Matthew F. Grady, Matthew L. Fazekas, Jonathan A. Santana, Rachel A. Coel, David R. Howell
Summary: The use of a clinical risk prediction tool accurately predicts the risk of persistent postconcussive symptoms (PPCSs) in youth athletes.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Article
Clinical Neurology
Allyssa K. Memmini, Michael J. Popovich, Kristen H. Schuyten, Stanley A. Herring, Katie L. Scott, James R. Clugston, Meeryo C. Choe, Christopher M. Bailey, M. Alison Brooks, Scott A. Anderson, Michael A. McCrea, Anthony P. Kontos, Jessica S. Wallace, Johna K. Register Mihalik, Tricia M. Kasamatsu, Tamara Valovich McLeod, Michelle L. Weber Rawlins, Traci R. Snedden, Matthew Kaplan, Briana Akani, La'Joya C. L. Orr, Rebecca E. Hasson, Sami F. Rifat, Steven P. Broglio
Summary: This study collected the experiences of university students with concussion history and academic stakeholders through interviews, and developed concussion management recommendations for institutions of higher learning using a multidisciplinary Delphi procedure. The findings indicated that students felt supported by their instructors, but academic faculty/staff lacked information and strategies to assist students. The Delphi procedure achieved consensus on 39 statements, including discharge documentation, multidisciplinary return-to-learn approaches, and processes to obtain academic supports for students after concussion.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2023)
