期刊
NEUROSURGERY
卷 78, 期 5, 页码 613-625出版社
OXFORD UNIV PRESS INC
DOI: 10.1227/NEU.0000000000001100
关键词
Arachnoid cyst; Dizziness; Headache; Prospective study; Quality of life; Surgical treatment
资金
- Health Region West, Norway [911065, 911475]
BACKGROUND:There is no previous prospective study on the outcome of surgical decompression of intracranial arachnoid cysts (AC).OBJECTIVE:To investigate if surgical fenestration for AC leads to change in patients' health-related quality of life.METHODS:Prospective study including 76 adult patients operated for AC. Patients responded to Short Form-36 and Glasgow Benefit Inventory quality of life questionnaires, and to visual analogue scales, assessing headache and dizziness pre- and postoperatively. Patient scores were compared with those of a large sample of healthy individuals.RESULTS:Preoperatively, 84.2% of the patients experienced headache and 70.1% dizziness. Mean pre- versus postoperative Visual Analogue Scale scores for headache and dizziness dropped from 45.6 to 25.7 and from 35.2 to 12.2, respectively. Preoperative Short Form-36 scores were significantly below age norms in all subscales, but improved after surgery into normal range in 7 out of 8 subscales for middle-aged and older patients. Younger patients' scores remained lower than age norm in 6 out of 8 subscales. A significant postoperative improvement was seen in 3 out of 4 Glasgow Benefit Inventory subscales. Improvement in headache and/or dizziness, but not preoperative cyst size or reduction in cyst volume, correlated with improvement in 6 out of 8 Short Form-36 subscales and 3 out of 4 Glasgow Benefit Inventory subscales. Only 1 patient experienced a severe complication causing permanent invalidity.CONCLUSION:Surgery for AC can be performed with a fairly low risk of complications and yields significant improvement in quality of life correlated to postoperative improvement in headache and dizziness. These findings may justify a more liberal approach to surgical treatment for AC.ABBREVIATIONS:AC, arachnoid cystsCSDH, chronic subdural hematomaCVRI, cyst volume reduction indexGBI, Glasgow Benefit InventorySDH, subdural hematomaSF-36, Short Form-36 (SF-36)QOL, quality of lifeVAS, Visual Analogue ScaleVP, ventriculoperitoneal
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