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A comprehensive review of glycosylated bacterial natural products

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CHEMICAL SOCIETY REVIEWS
卷 44, 期 21, 页码 7591-7697

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cs00426d

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  1. University of Kentucky College of Pharmacy
  2. University of Kentucky Markey Cancer Center
  3. National Center for Advancing Translational Sciences [UL1TR000117]
  4. National Institutes of Health (NIH) [R37 AI52218, R01 CA84374]

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A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites reported in the scientific literature up through early 2013 is presented. This comprehensive analysis of 15 940 bacterial natural products revealed 3426 glycosides containing 344 distinct appended carbohydrates and highlights a range of unique opportunities for future biosynthetic study and glycodiversification efforts.

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