hnRNPA2/B1 Function in Neurodegeneration: It's a Gain, Not a Loss

hnRNPA2B1 is linked to several neurodegenerative disorders, yet its roles in the CNS have been largely unknown. In this issue of Neuron, Martinez et al. (2016) present the first transcriptome-wide analysis of hnRNPA2B1 targets and function in the nervous system.