期刊
NEUROLOGIC CLINICS
卷 34, 期 3, 页码 699-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ncl.2016.04.008
关键词
Atypical Alzheimer's; Fluent aphasia; Late-onset dementia; Rapid dementia
资金
- Donors Cure Foundation New Vision Award
- Gerstner Family Career Development Award
- Mayo Clinic Alzheimer's Disease Research Center (ADRC) grant [P50AG 16574-14]
Many dementia subtypes have more shared signs and symptoms than defining ones. We review 8 cases with 4 overlapping syndromes and demonstrate how to distinguish the cases. These include focal cortical presentations of Alzheimer's disease (AD; posterior cortical atrophy and corticobasal syndrome [CBS]), fluent aphasia (semantic dementia and log-openic aphasia), late-onset slowly progressive dementia (hippocampal sclerosis and limbic predominant AD) and rapidly progressive dementia (Creutzfeldt Jakob disease and limbic encephalitis). Recognizing the different syndromes can help the clinician to improve their diagnostic skills, leading to improved patient outcomes by early and accurate diagnosis, prompt treatment, and appropriate counseling and guidance.
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