Article
Pharmacology & Pharmacy
Yu-Tung Lai, Chung-Yu Chen, Ming-Jong Bair
Summary: The study revealed a decreasing trend in the incidence and prevalence of IBS in Taiwan from 2012 to 2018, with over 70% of patients receiving treatment and antispasmodics being the most commonly prescribed medication. However, only 48.58% of patients returned for a follow-up visit within 1 year of IBS diagnosis.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Nutrition & Dietetics
Kelly Anne Erdman, Kim Wagner Jones, Robyn F. Madden, Nancy Gammack, Jill A. Parnell
Summary: Runners with IBD/IBS and reflux tend to avoid trigger foods in their pre-race meals, but they also consume potentially aggravating foods. Nutrition advice may be beneficial in managing GIS symptoms in these individuals.
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Biochemistry & Molecular Biology
Sholpan Omarova, Karem Awad, Verena Moos, Christoph Puening, Greta Goelz, Jorg-Dieter Schulzke, Roland Buecker
Summary: This study observed patients with persistent PI-IBS symptoms after C. jejuni infection and found that the epithelial resistance of the colon epithelium was unaltered, but the permeability of HRP increased and some inflammation-related markers were elevated. Therefore, targeting these mechanisms caused by the infection may help reduce sequelae such as PI-IBS.
Review
Immunology
Mancai Wang, Xiaofeng Xie, Songbo Zhao, Xiaojuan Ma, Zheyuan Wang, Youcheng Zhang
Summary: This systematic review and meta-analysis found that a single stool FMT is effective and safe for patients with IBS. However, the effectiveness of FMT may be influenced by certain factors, and the relationship between the gut microbiome and the effect of FMT for IBS remains unclear.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Nutrition & Dietetics
Esther Colomier, Lukas Van Oudenhove, Jan Tack, Lena Boehn, Sean Bennet, Sanna Nybacka, Stine Stoersrud, Lena oehman, Hans Toernblom, Magnus Simren
Summary: This study investigated predictors of symptom improvement in patients with irritable bowel syndrome following low FODMAP and traditional IBS diets, finding that psychological, nutritional, and microbial factors play a role in symptom improvement.
Article
Nutrition & Dietetics
Annamaria Altomare, Federica Del Chierico, Giulia Rocchi, Sara Emerenziani, Chiara Nuglio, Lorenza Putignani, Silvia Angeletti, Alessandra Lo Presti, Massimo Ciccozzi, Alessandra Russo, Silvia Cocca, Mentore Ribolsi, Maurizio Muscaritoli, Michele Cicala, Michele Pier Luca Guarino
Summary: This study revealed an association between nutrient intake, adherence to Mediterranean diet, IBS symptoms, and gut microbiota in IBS patients. Lower adherence to Mediterranean diet was correlated with severe abdominal pain and higher flatulence in IBS patients, indicating a potential connection between dietary patterns and gut microbial biomarkers in IBS.
Article
Gastroenterology & Hepatology
Michael Camilleri, Guy Boeckxstaens
Summary: This article evaluates the evidence that targeted pathophysiological mechanisms and customized treatments can be an alternative approach to treating patients with irritable bowel syndrome (IBS). The authors conducted a literature review on the mechanisms and treatments of IBS, identifying various noninvasive clinical tests that can assess the underlying mechanisms responsible for symptom generation. These mechanisms include rectal evacuation disorders, abnormal transit, visceral hypersensitivity or hypervigilance, bile acid diarrhea, sugar intolerances, barrier dysfunction, the microbiome, immune activation, and chemicals released by these mechanisms. The authors also recognized the basic molecular mechanisms contributing to these pathophysiologies, offering opportunities for interventions with medications targeted at specific food components, receptors, and potentially the microbiome. Although the evidence supporting interventions for each mechanism varies, the current state-of-the-art allows for a shift from symptom-based treatment to individualized treatment guided by pathophysiology and clinically identified biomarkers.
Article
Gastroenterology & Hepatology
Colleen H. Parker, Bruce D. Naliboff, Wendy Shih, Angela P. Presson, Lisa Kilpatrick, Arpana Gupta, Cathy Liu, Laurie A. Keefer, Jenny S. Sauk, Robert Hirten, Bruce E. Sands, Lin Chang
Summary: The study found that resilience is lower in patients with Irritable Bowel Syndrome (IBS) compared to the general population, leading to more severe symptoms. The impact of global mental health on resilience is more significant in IBS compared to the general population, and early adverse life events also decrease the ability to bounce back from adversity. While resilience in IBS is lower than the general US population, it is comparable to other chronic gastrointestinal conditions.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Gastroenterology & Hepatology
Vivek C. Goodoory, Mais Khasawneh, Christopher J. Black, Eamonn M. M. Quigley, Paul Moayyedi, Alexander C. Ford
Summary: This article conducted a meta-analysis to study the efficacy of probiotics in the treatment of irritable bowel syndrome (IBS). The study found that certain combinations of probiotics or strains may be beneficial for IBS, but the certainty of the evidence was low.
Article
Gastroenterology & Hepatology
Zachary E. McPherson, Henrik T. Sorensen, Erzsebet Horvath-Puho, Ashish Agar, Minas T. Coroneo, Andrew White, Ian C. Francis, Louis R. Pasquale, Jae H. Kang, Sven Pettersson, Nicholas J. Talley, Mark A. McEvoy
Summary: Two large European cohort studies suggest that individuals with irritable bowel syndrome (IBS) may have an increased risk of developing glaucoma.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2021)
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Vittoria Terrigno, Florencia Carbone, Jan Tack, Michele Cicala, Michele Pier Luca Guarino
Summary: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. The exact cause of IBS is not fully understood, but it is believed to involve a combination of factors such as abnormal gut motility, inflammation, increased intestinal permeability, and sensitivity. Diet and gut microbiota have also been identified as important contributors to IBS. This review examines the effects of dietary components, functional foods, prebiotics, probiotics, and symbiotics on symptoms and gut microbiota in individuals with IBS-C.
Review
Medicine, General & Internal
Cristian-Ioan Babos, Daniel-Corneliu Leucuta, Dan Lucian Dumitrascu
Summary: This study assessed the effectiveness of meditation/mindfulness in improving symptoms severity, quality of life, and other associated mental conditions in patients with irritable bowel syndrome (IBS). The meta-analysis results showed statistically significant improvements in symptom score, quality of life, spiritual scale, and pain score in the mindfulness group compared to the control group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Zulun Zhang, Qianqian Li, Sheng Zhang, Yujie Liu, Gaochen Lu, Quan Wen, Bota Cui, Fuquan Zhang, Faming Zhang
Summary: This study aimed to evaluate the efficacy of washed microbiota transplantation (WMT) on sleep disturbances, and psychological and gastrointestinal symptoms among patients with irritable bowel syndrome (IBS). The results showed significant improvements in sleep quality, anxiety, depression, gastrointestinal symptoms, and IBS severity after WMT. Baseline sleep duration scores were identified as an independent predictive factor for sleep improvement.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Review
Biochemical Research Methods
Diana Zarei, Amene Saghazadeh, Nima Rezaei
Summary: This literature review examines the use of cluster analysis in irritable bowel syndrome (IBS) patients. It reveals that IBS can be classified into different subgroups based on various factors. However, the number of clusters varies across studies due to methodological heterogeneity. The research further explores the clinical symptoms, rectal perception, immunological findings, and microbial composition of IBS.
BMC BIOINFORMATICS
(2023)
Article
Neurosciences
Sanaz Soltani, Mehdi Shayanfar, Sanaz Benisi-Kohansal, Minoo Mohammad-Shirazi, Giuve Sharifi, Abolghassem Djazayeri, Ahmad Esmaillzadeh
Summary: This study aims to examine the association between adherence to the MIND diet and the risk of glioma. The results suggest that individuals with greater adherence to the MIND diet are less likely to develop glioma.
NUTRITIONAL NEUROSCIENCE
(2022)
Review
Food Science & Technology
Mohammad Reza Amini, Azadeh Aminianfar, Sina Naghshi, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study aimed to summarize earlier randomized controlled trials on the effects of ketogenic diet on body composition and anthropometric measures. The results showed that ketogenic diet had significant effects on body weight, body mass index, fat mass, fat-free mass, lean body mass, waist circumference, visceral adipose tissue, and percentage body fat. However, the effectiveness of the long-term effect of this dietary pattern is unclear.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Neurosciences
Somaye Rigi, Seyed Mohammad Mousavi, Forough Shakeri, Ammar Hassanzadeh Keshteli, Sanaz Benisi-Kohansal, Mohammad Saadatnia, Ahmad Esmaillzadeh
Summary: The study found evidence of a significant inverse association between dietary phytochemical index (DPI) and the odds of stroke in adults, with individuals in the highest DPI tertile having a lower risk of stroke. Further prospective studies are needed to confirm this association.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
Saeedeh Nouri-Majd, Asma Salari-Moghaddam, Ammar Hassanzadeh Keshteli, Ahmad Esmaillzadeh, Peyman Adibi
Summary: The study found a significant inverse association between consumption of a proinflammatory diet and general obesity, especially pronounced in women. However, no significant association was found between DIP scores and abdominal obesity.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2022)
Article
Neurosciences
Faezeh Saghafian, Maryam Hajishafiee, Parisa Rouhani, Parvane Saneei
Summary: In this meta-analysis, a negative association was found between dietary fiber intake and depression. Each 5-g increase in total dietary fiber intake was associated with a 5% reduction in risk of depression in adults.
NUTRITIONAL NEUROSCIENCE
(2023)
Review
Food Science & Technology
Farzaneh Asoudeh, Amir Bagheri, Bagher Larijani, Ahmad Esmaillzadeh
Summary: The association between coffee consumption and risk of fracture is inconclusive, while caffeine intake is positively associated with risk, according to this updated systematic review and meta-analysis.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Sara Ebrahimi Mousavi, Amir Bagheri, Sanaz Benisi-Kohansal, Leila Azadbakht, Ahmad Esmaillzadeh
Summary: The present study aimed to assess the association between consumption of a diabetes risk reduction diet (DRRD) and breast cancer. The results showed that individuals with high adherence to DRRD had a 0.41 times lower risk of breast cancer, especially among postmenopausal and normal-weight women.
FRONTIERS IN NUTRITION
(2022)
Review
Nutrition & Dietetics
Amir Bagheri, Sanaz Soltani, Farzaneh Asoudeh, Ahmad Esmaillzadeh
Summary: Oral omega-3 supplementation significantly increased serum albumin concentrations in hospitalized patients with cancer, patients on dialysis, and those with hypoalbuminemia. Favorable effects on pre-albumin levels were observed in cancer patients and patients with gastrointestinal and hepatologic diseases. However, no significant effect on the CRP/albumin ratio was found.
Article
Nutrition & Dietetics
Sobhan Mohammadi, Keyhan Lotfi, Saeideh Mirzaei, Ali Asadi, Masoumeh Akhlaghi, Parvane Saneei
Summary: This study found that adolescents with higher intakes of dietary antioxidants have a lower likelihood of being metabolically unhealthy obese (MUO) according to the International Diabetes Federation (IDF) criteria. However, there was no substantial association found when considering the IDF/HOMA-IR criteria. Further prospective cohort studies are needed to confirm these findings.
Article
Chemistry, Medicinal
Zahra Hajhashemy, Fateme Sadat Mirenayat, Mansour Siavash, Parvane Saneei
Summary: This study investigated the impact of sumac supplementation on patients with MetS. The results showed that sumac supplementation can improve the antioxidant defense system, but has no significant effect on insulin resistance, inflammation, or oxidative stress.
PHYTOTHERAPY RESEARCH
(2023)
Review
Public, Environmental & Occupational Health
Helda Tutunchi, Sina Naghshi, Mohammad Naemi, Fatemeh Naeini, Ahmad Esmaillzadeh
Summary: This systematic review and meta-analysis found that higher yogurt consumption was associated with a lower risk of mortality from all causes and cardiovascular disease (CVD), but not with cancer mortality. Each additional serving of yogurt per day was significantly associated with a reduced risk of all-cause and CVD mortality.
PUBLIC HEALTH NUTRITION
(2023)
Review
Nutrition & Dietetics
Nikan Zargarzadeh, Seyed Mohammad Mousavi, Heitor O. Santos, Dagfinn Aune, Shirin Hasani-Ranjbar, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study examined the potential dose-response relationship between legume consumption and mortality rates in the general population. The results showed that higher legume intake was associated with a reduced risk of all-cause and stroke mortality, but there was no significant association with cardiovascular disease, coronary heart disease, and cancer mortality.
ADVANCES IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
Farzaneh Asoudeh, Seyed Mohammad Mousavi, Ammar Hassanzadeh Keshteli, Shirin Hasani-Ranjbar, Bagher Larijani, Ahmad Esmaillzadeh, Peyman Adibi
Summary: This study aimed to investigate the association between plant-based dietary index (PDI) and the prevalence of general and abdominal obesity. The analysis of data from 6,724 Iranian adults showed no significant association between PDI and general or abdominal obesity.
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2023)
Letter
Nutrition & Dietetics
Fateme Shafiei, Asma Salari-Moghaddam, Bagher Larijani, Ahmad Esmaillzadeh
Summary: Based on reader feedback, we made revisions to our original study article and re-analyzed the data. In the corrected version, we found a significant inverse association between adherence to the Mediterranean diet and risk of depression in cohort studies (overall hazard ratio, 0.81; 95% confidence interval, 0.70-0.94). Additionally, combining 8 cross-sectional studies on the association between adherence to the Mediterranean diet and depression, we found a significant inverse association (overall odds ratio, 0.81; 95% confidence interval, 0.71-0.92).
Review
Nutrition & Dietetics
Parisa Rouhani, Elahe Mokhtari, Keyhan Lotfi, Parvane Saneei
Summary: A dose-response meta-analysis of observational studies found a negative association between blood 25(OH)D levels and the risk of preeclampsia (PE). This suggests that adequate levels of 25(OH)D may reduce the risk of PE.
