Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis
出版年份 2016 全文链接
标题
Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis
作者
关键词
-
出版物
NEURO-ONCOLOGY
Volume 18, Issue 5, Pages 624-638
出版商
Oxford University Press (OUP)
发表日期
2016-02-07
DOI
10.1093/neuonc/nov200
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ketotifen suppression of NF1 neurofibroma growth over 30 years
- (2015) Vincent M. Riccardi AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas
- (2015) Stéphane Goutagny et al. JOURNAL OF NEURO-ONCOLOGY
- Gamma Knife radiosurgery for meningiomas in patients with neurofibromatosis Type 2
- (2015) Ann Liu et al. JOURNAL OF NEUROSURGERY
- Neurofibromin 1 (NF1) Defects Are Common in Human Ovarian Serous Carcinomas and Co-occur with TP53 Mutations
- (2015) Navneet Sangha et al. NEOPLASIA
- Relationship between whole-body tumor burden, clinical phenotype, and quality of life in patients with neurofibromatosis
- (2014) Vanessa L. Merker et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus
- (2014) Wei Li et al. CANCER CELL
- Combined MEK Inhibition and BMP2 Treatment Promotes Osteoblast Differentiation and Bone Healing inNf1Osx−/−Mice
- (2014) Jean de la Croix Ndong et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prolonged survival in adult neurofibromatosis type I patients with recurrent high-grade gliomas treated with bevacizumab
- (2014) Brett J. Theeler et al. JOURNAL OF NEUROLOGY
- Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2
- (2014) Rosalie E. Ferner et al. JOURNAL OF NEUROLOGY
- Clinical course of vestibular schwannoma in pediatric neurofibromatosis Type 2
- (2014) Jung Won Choi et al. Journal of Neurosurgery-Pediatrics
- Li-Fraumeni syndrome: cancer risk assessment and clinical management
- (2014) Kate A. McBride et al. Nature Reviews Clinical Oncology
- Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas
- (2014) B. C. Widemann et al. NEURO-ONCOLOGY
- Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth
- (2014) Aparna Kaul et al. NEURO-ONCOLOGY
- CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011
- (2014) Q. T. Ostrom et al. NEURO-ONCOLOGY
- Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study
- (2014) B. Weiss et al. NEURO-ONCOLOGY
- Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis
- (2014) M. J. Smith et al. NEUROLOGY
- Clinical response to bevacizumab in schwannomatosis
- (2014) J. Blakeley et al. NEUROLOGY
- Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas
- (2014) Brigitte C. Widemann et al. PEDIATRIC BLOOD & CANCER
- Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship
- (2014) I. M. Shapiro et al. Science Translational Medicine
- Defining Key Signaling Nodes and Therapeutic Biomarkers in NF1-Mutant Cancers
- (2014) C. F. Malone et al. Cancer Discovery
- SMARCB1 mutations in schwannomatosis and genotype correlations with rhabdoid tumors
- (2014) Miriam J. Smith et al. Cancer Genetics
- Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system
- (2014) Weiwei Wang et al. eLife
- Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas
- (2014) Robert A. Avery et al. JAMA Ophthalmology
- Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria
- (2013) Scott R. Plotkin et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Optimizing biologically targeted clinical trials for neurofibromatosis
- (2013) David H Gutmann et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Approaches to Treating NF1 Tibial Pseudarthrosis
- (2013) David A. Stevenson et al. JOURNAL OF PEDIATRIC ORTHOPAEDICS
- Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
- (2013) Priscilla K Brastianos et al. NATURE GENETICS
- Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
- (2013) Cigall Kadoch et al. NATURE GENETICS
- Phase II study of everolimus in children and adults with neurofibromatosis type 2 and progressive vestibular schwannomas
- (2013) Matthias A. Karajannis et al. NEURO-ONCOLOGY
- Hearing and facial function outcomes for neurofibromatosis 2 clinical trials
- (2013) S. R. Plotkin et al. NEUROLOGY
- Conclusions and future directions for the REiNS International Collaboration
- (2013) B. C. Widemann et al. NEUROLOGY
- Recommendations for imaging tumor response in neurofibromatosis clinical trials
- (2013) E. Dombi et al. NEUROLOGY
- Functional outcome measures for NF1-associated optic pathway glioma clinical trials
- (2013) M. J. Fisher et al. NEUROLOGY
- Conservative Management of Bilateral Vestibular Schwannomas in Neurofibromatosis Type 2 Patients
- (2013) Matthieu Peyre et al. NEUROSURGERY
- Natural History of Vestibular Schwannoma Growth and Hearing Decline in Newly Diagnosed Neurofibromatosis Type 2 Patients
- (2013) Scott R. Plotkin et al. OTOLOGY & NEUROTOLOGY
- Marked Recovery of Vision in Children With Optic Pathway Gliomas Treated With Bevacizumab
- (2013) Robert A. Avery et al. JAMA Ophthalmology
- Abstract 4686: Requirements of Gαi1 and Gαi3 for brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) induced PI3K/AKT and MAPK signaling as well as neuronal survival and migration
- (2012) Cong Cao et al. CANCER RESEARCH
- Internal tumor burden in neurofibromatosis Type I patients with large NF1 deletions
- (2012) Lan Kluwe et al. GENES CHROMOSOMES & CANCER
- Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (NF1) as a Breast Cancer Driver
- (2012) M. D. Wallace et al. GENETICS
- Spectrum and Prevalence of Vasculopathy in Pediatric Neurofibromatosis Type 1
- (2012) Bonnie Kaas et al. JOURNAL OF CHILD NEUROLOGY
- Life expectancy in hereditary cancer predisposing diseases: an observational study
- (2012) Anna Wilding et al. JOURNAL OF MEDICAL GENETICS
- Long-term natural history of neurofibromatosis Type 2–associated intracranial tumors
- (2012) Michael S. Dirks et al. JOURNAL OF NEUROSURGERY
- Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial
- (2012) Kent A Robertson et al. LANCET ONCOLOGY
- Regulation of mTOR Complex 2 Signaling in Neurofibromatosis 2-Deficient Target Cell Types
- (2012) M. F. James et al. MOLECULAR CANCER RESEARCH
- Phase II trial of lapatinib in adult and pediatric patients with neurofibromatosis type 2 and progressive vestibular schwannomas
- (2012) Matthias A. Karajannis et al. NEURO-ONCOLOGY
- Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis
- (2012) M. J. Fisher et al. NEURO-ONCOLOGY
- Frequency of SMARCB1 mutations in familial and sporadic schwannomatosis
- (2012) Miriam J. Smith et al. NEUROGENETICS
- The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38SAPK pathway
- (2012) R F Hennigan et al. ONCOGENE
- Clinical Features of Schwannomatosis: A Retrospective Analysis of 87 Patients
- (2012) V. L. Merker et al. ONCOLOGIST
- Bevacizumab for Progressive Vestibular Schwannoma in Neurofibromatosis Type 2
- (2012) Scott R. Plotkin et al. OTOLOGY & NEUROTOLOGY
- Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas
- (2012) AeRang Kim et al. PEDIATRIC BLOOD & CANCER
- Vestibular schwannomas occur in schwannomatosis and should not be considered an exclusion criterion for clinical diagnosis
- (2011) Miriam J. Smith et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Pathogenesis of Plexiform Neurofibroma: Tumor-Stromal/Hematopoietic Interactions in Tumor Progression
- (2011) Karl Staser et al. Annual Review of Pathology-Mechanisms of Disease
- SMARCB1/INI1 germline mutations contribute to 10% of sporadic schwannomatosis
- (2011) Guillaume Rousseau et al. BMC Neurology
- A phase 2 study of pegylated interferon α-2b (PEG-Intron®) in children with diffuse intrinsic pontine glioma
- (2011) Katherine Warren et al. CANCER
- Dose-Dependent Effects of Focal Fractionated Irradiation on Secondary Malignant Neoplasms in Nf1 Mutant Mice
- (2011) J. L. Nakamura et al. CANCER RESEARCH
- Genetic testing and screening of individuals at risk of NF2
- (2011) DG Evans et al. CLINICAL GENETICS
- Pediatric Plexiform Neurofibromas: Impact on Morbidity and Mortality in Neurofibromatosis Type 1
- (2011) Carlos E. Prada et al. JOURNAL OF PEDIATRICS
- Pulmonary Hypertension in Patients With Neurofibromatosis Type I
- (2011) David Montani et al. MEDICINE
- Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2
- (2011) S. Ammoun et al. NEURO-ONCOLOGY
- AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas
- (2011) M. L. Bush et al. NEURO-ONCOLOGY
- Germline SMARCB1 mutation predisposes to multiple meningiomas and schwannomas with preferential location of cranial meningiomas at the falx cerebri
- (2011) Pepijn van den Munckhof et al. NEUROGENETICS
- Phase I trial of pegylated interferon- -2b in young patients with plexiform neurofibromas
- (2011) R. I. Jakacki et al. NEUROLOGY
- Merlin/NF2 Functions Upstream of the Nuclear E3 Ubiquitin Ligase CRL4DCAF1 to Suppress Oncogenic Gene Expression
- (2011) J. Cooper et al. Science Signaling
- Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service
- (2010) D.G. Evans et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations
- (2010) J. Krosl et al. BLOOD
- Anti–Vascular Endothelial Growth Factor Therapies as a Novel Therapeutic Approach to Treating Neurofibromatosis-Related Tumors
- (2010) Hon Kit Wong et al. CANCER RESEARCH
- Merlin, a “Magic” Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival
- (2010) Ivan Stamenkovic et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: It's time to exchange!
- (2010) Sonia Albini et al. EXPERIMENTAL CELL RESEARCH
- SMARCB1 mutations are not a common cause of multiple meningiomas
- (2010) K. D. Hadfield et al. JOURNAL OF MEDICAL GENETICS
- Meningiomas and neurofibromatosis
- (2010) Stéphane Goutagny et al. JOURNAL OF NEURO-ONCOLOGY
- CXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice
- (2010) Tao Sun et al. JOURNAL OF NEUROIMMUNOLOGY
- The molecular pathology of cancer
- (2010) Timothy J. R. Harris et al. Nature Reviews Clinical Oncology
- The Diagnostic and Clinical Significance of Café-au-lait Macules
- (2010) Kara N. Shah PEDIATRIC CLINICS OF NORTH AMERICA
- Consensus Recommendations to Accelerate Clinical Trials for Neurofibromatosis Type 2
- (2009) D. G. Evans et al. CLINICAL CANCER RESEARCH
- Alterations in the SMARCB1 (INI1) tumor suppressor gene in familial schwannomatosis
- (2009) C Boyd et al. CLINICAL GENETICS
- ATP-dependent chromatin remodeling in neural development
- (2009) Andrew S Yoo et al. CURRENT OPINION IN NEUROBIOLOGY
- Gliomas in patients with neurofibromatosis type 1
- (2009) Anne C Albers et al. Expert Review of Neurotherapeutics
- Schwannomatosis associated with multiple meningiomas due to a familial SMARCB1 mutation
- (2009) Costanza Bacci et al. NEUROGENETICS
- THREE-DIMENSIONAL VOLUMETRICS FOR TRACKING VESTIBULAR SCHWANNOMA GROWTH IN NEUROFIBROMATOSIS TYPE II
- (2009) Gordon J. Harris et al. NEUROSURGERY
- Hearing Improvement after Bevacizumab in Patients with Neurofibromatosis Type 2
- (2009) Scott R. Plotkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Concordance of Bilateral Vestibular Schwannoma Growth and Hearing Changes in Neurofibromatosis 2
- (2009) Laurel M. Fisher et al. OTOLOGY & NEUROTOLOGY
- Three new datasets supporting use of the Numerical Rating Scale (NRS-11) for children’s self-reports of pain intensity
- (2009) Carl L. von Baeyer et al. PAIN
- Clinical Experience With Radiation Therapy in the Management of Neurofibromatosis-Associated Central Nervous System Tumors
- (2008) Stacy Wentworth et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Magic but treatable? Tumours due to loss of Merlin
- (2007) C. O. Hanemann BRAIN
- Evidence of a four-hit mechanism involvingSMARCB1andNF2in schwannomatosis-associated schwannomas
- (2007) Roberta Sestini et al. HUMAN MUTATION
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started