Phytochemical analysis, in vitro and in silico effects from Alstonia boonei De Wild stem bark on selected digestive enzymes and adipogenesis in 3T3-L1 preadipocytes

Identification of promising multi-targeting inhibitors of obesity from Vernonia amygdalina through computational analysis

(2022) Oludare M. Ogunyemi et al.   MOLECULAR DIVERSITY

Experiences of weight stigmatization in the Israeli healthcare system among overweight and obese individuals

(2022) Lena Sagi-Dain et al.   Israel Journal of Health Policy Research

Inhibition mechanism of alpha-amylase, a diabetes target, by a steroidal pregnane and pregnane glycosides derived from Gongronema latifolium Benth

(2022) Oludare M. Ogunyemi et al.   Frontiers in Molecular Biosciences

GLP-1 Agonist to Treat Obesity and Prevent Cardiovascular Disease: What Have We Achieved so Far?

(2022) Maurício Reis Pedrosa et al.   Current Atherosclerosis Reports

Diagnosis of obesity based on body composition‐associated health risks—Time for a change in paradigm

(2021) Anja Bosy‐Westphal et al.   Obesity Reviews

Screening of in vitro and in silico α-amylase, α-glucosidase, and lipase inhibitory activity of oxyprenylated natural compounds and semisynthetic derivatives

(2021) Immacolata Faraone et al.   PHYTOCHEMISTRY

Cassia fistula Leaves; UHPLC-QTOF-MS/MS Based Metabolite Profiling and Molecular Docking Insights to Explore Bioactives Role towards Inhibition of Pancreatic Lipase

(2021) Zain Ul Aabideen et al.   Plants-Basel

Anti-obesity drug discovery: advances and challenges

(2021) Timo D. Müller et al.   NATURE REVIEWS DRUG DISCOVERY

Lipase Inhibitors for Obesity: A Review

(2020) Tian-Tian Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Exploring Aurone Derivatives as Potential Human Pancreatic Lipase Inhibitors through Molecular Docking and Molecular Dynamics Simulations

(2020) Phuong Thuy Viet Nguyen et al.   MOLECULES

Synthesis, α-amylase inhibition and molecular docking study of bisindolylmethane sulfonamide derivatives

(2019) Muhammad Taha et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study

(2019) Fazal Rahim et al.   BIOORGANIC CHEMISTRY

Antidiabetic activities of chloroform fraction of Anthocleista vogelii Planch root bark in rats with diet- and alloxan-induced obesity-diabetes

(2018) Gabriel O. Anyanwu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Suppression of adipocyte differentiation and lipid accumulation by stearidonic acid (SDA) in 3T3-L1 cells

(2017) Yueru Li et al.   Lipids in Health and Disease

Medicinal plant phytochemicals and their inhibitory activities against pancreatic lipase: molecular docking combined with molecular dynamics simulation approach

(2017) Bilal Ahmed et al.   NATURAL PRODUCT RESEARCH

Kinetics of α-glucosidase inhibition by different fractions of three species of Labiatae extracts: a new diabetes treatment model

(2017) Sahere Rouzbehan et al.   PHARMACEUTICAL BIOLOGY

Obesity

(2017) Pedro González-Muniesa et al.   Nature Reviews Disease Primers

FDA-Approved Anti-Obesity Drugs in the United States

(2016) Homayoun L. Daneschvar et al.   AMERICAN JOURNAL OF MEDICINE

Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

(2014) Thomas Svava Nielsen et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

beta-Amyrin and alpha-amyrin acetate isolated from the stem bark ofAlstonia booneidisplay profound anti-inflammatory activity

(2014) Nkeoma Nkasi Okoye et al.   PHARMACEUTICAL BIOLOGY

Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro

(2013) Michelle H. Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

GalaxyRefine: protein structure refinement driven by side-chain repacking

(2013) Lim Heo et al.   NUCLEIC ACIDS RESEARCH

Screening of Crude Plant Extracts with Anti-Obesity Activity

(2012) Changhyun Roh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Order and Disorder: Differential Structural Impacts of Myricetin and Ethyl Caffeate on Human Amylase, an Antidiabetic Target

(2012) Leslie K. Williams et al.   JOURNAL OF MEDICINAL CHEMISTRY

Studies on α-Glucosidase Inhibitors Development: Magic Molecules for the Treatment of Carbohydrate Mediated Diseases

(2012) N. S.H.N. Moorthy et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Maslinic acid, a natural inhibitor of glycogen phosphorylase, reduces cerebral ischemic injury in hyperglycemic rats by GLT-1 up-regulation

(2011) Teng Guan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose

(2010) Keizo Yamamoto et al.   FEBS Journal

Inhibitory effects of estrogens on digestive enzymes, insulin deficiency, and pancreas toxicity in diabetic rats

(2010) Khaled Hamden et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Anti-lipase and lipolytic activities of ursolic acid isolated from the roots of Actinidia arguta

(2009) Junghyun Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The acute effects of the thermogenic supplement Meltdown on energy expenditure, fat oxidation, and hemodynamic responses in young, healthy males

(2008) Jean Jitomir et al.   Journal of the International Society of Sports Nutrition