Lysine deacetylase inhibition attenuates hypertension and is accompanied by acetylation of mineralocorticoid receptor instead of histone acetylation in spontaneously hypertensive rats

Lysine acetyltransferases cyclic adenosine monophosphate response element-binding binding protein and acetyltransferase p300 attenuate transcriptional activity of the mineralocorticoid receptor through its acetylation

(2015) Minchul Seo et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Histone deacetylases in cardiac fibrosis: Current perspectives for therapy

(2013) Hui Tao et al.   CELLULAR SIGNALLING

Histone Deacetylase Inhibition Attenuates Transcriptional Activity of Mineralocorticoid Receptor Through Its Acetylation and Prevents Development of Hypertension

(2013) Hae-Ahm Lee et al.   CIRCULATION RESEARCH

Mineralocorticoid Receptors in Vascular Disease: Connecting Molecular Pathways to Clinical Implications

(2013) Adam P. McGraw et al.   Current Atherosclerosis Reports

Nuclear Shuttling Precedes Dimerization in Mineralocorticoid Receptor Signaling

(2012) Claudia Grossmann et al.   CHEMISTRY & BIOLOGY

Histone Deacetylation Inhibition in Pulmonary Hypertension

(2012) Lan Zhao et al.   CIRCULATION

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

(2012) A. Galmozzi et al.   DIABETES

Long-term food restriction attenuates age-related changes in the expression of renal aldosterone-sensitive sodium transporters in Wistar-Kyoto rats: A comparison with SHR

(2012) Vanda Pinto et al.   EXPERIMENTAL GERONTOLOGY

Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats

(2012) Toshiaki Nakagaki et al.   HYPERTENSION RESEARCH

Regulation of the androgen receptor by post-translational modifications

(2012) Kelly Coffey et al.   JOURNAL OF ENDOCRINOLOGY

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nonhistone protein acetylation as cancer therapy targets

(2010) Brahma N Singh et al.   Expert Review of Anticancer Therapy

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

Acetylation and nuclear receptor action

(2010) Chenguang Wang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Progesterone Receptor Hinge Region Regulates the Kinetics of Transcriptional Responses Through Acetylation, Phosphorylation, and Nuclear Retention

(2010) Andrea R. Daniel et al.   MOLECULAR ENDOCRINOLOGY

Weight gain following treatment with valproic acid: pathogenetic mechanisms and clinical implications

(2010) A. Verrotti et al.   Obesity Reviews

HDACi – Targets beyond chromatin

(2009) Marc Buchwald et al.   CANCER LETTERS

Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications

(2009) Nancy Nader et al.   FASEB JOURNAL

The mineralocorticoid receptor and its coregulators

(2009) Jun Yang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

A Lifetime of Aldosterone Excess: Long-Term Consequences of Altered Regulation of Aldosterone Production for Cardiovascular Function

(2008) John M. C. Connell et al.   ENDOCRINE REVIEWS

Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain

(2008) Siem van der Laan et al.   JOURNAL OF NEUROCHEMISTRY

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

Present and future drug treatments for chronic kidney diseases: evolving targets in renoprotection

(2008) Norberto Perico et al.   NATURE REVIEWS DRUG DISCOVERY

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS