Article
Chemistry, Multidisciplinary
Zhouliang Tan, Yunjiao Li, Changlong Lei, Yue Li, Xiaoming Xi, Shijie Jiang, Feixiang Wu, Zhenjiang He
Summary: A novel MgTiO3 coating with the same lattice structure as the anode is constructed to achieve ultra-stable mechanical integrity, prevent direct contact between the anode and the electrolyte, and stabilize the interfacial structure. The coating also forms a superstructure that effectively alleviates lattice changes and ion migration. The modified anode exhibits desirable capacity retention and high-voltage stability.
Review
Chemistry, Physical
Xi Jin, Yuxuan Yang, Tao Zhao, Xiaoxue Wu, Baoze Liu, Mingyue Han, Weiqiang Chen, Tongsheng Chen, Jin-Song Hu, Yan Jiang
Summary: Perovskite solar cells have made significant breakthroughs in efficiency, stability, and large-area manufacturing. However, the toxicity of lead in perovskite is a significant concern. This Review provides an overview of the toxicity of lead, discusses the life cycles of perovskite solar cells, and presents strategies to mitigate lead leakage risks.
ACS ENERGY LETTERS
(2022)
Article
Multidisciplinary Sciences
Moritz Muehlhofer, Carsten Peters, Thomas Kriehuber, Marina Kreuzeder, Pamina Kazman, Natalia Rodina, Bernd Reif, Martin Haslbeck, Sevil Weinkauf, Johannes Buchner
Summary: This study provides insights into the activation mechanism of small heat shock protein Hsp26. By analyzing phospho-mimetic mutants and cryo-EM structures, it reveals that phosphorylation relieves the intrinsic inhibition of chaperone activity and activates protein binding ability of Hsp26.
NATURE COMMUNICATIONS
(2021)
Article
Cell Biology
Sandeep C. Chaudhary, Sana Khalid, Victoria Smethurst, Daisy Monier, James Mobley, Alexis Huet, James F. Conway, Dobrawa Napierala
CONNECTIVE TISSUE RESEARCH
(2018)
Article
Virology
Laura L. Ruhge, Alexis G. E. Huet, James F. Conway, Gregory A. Smith
JOURNAL OF VIROLOGY
(2018)
Article
Biochemistry & Molecular Biology
Yudong Wang, Johan Palmfeldt, Niels Gregersen, Alexander M. Makhov, James F. Conway, Meicheng Wang, Stephen P. McCalley, Shrabani Basu, Hana Alharbi, Claudette St Croix, Michael J. Calderon, Simon Watkins, Jerry Vockley
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Patricia L. Campbell, Robert L. Duda, Jamie Nassur, James F. Conway, Alexis Huet
JOURNAL OF MOLECULAR BIOLOGY
(2020)
Article
Multidisciplinary Sciences
Fengbin Wang, Ying Liu, Zhangli Su, Tomasz Osinski, Guilherme A. P. de Oliveira, James F. Conway, Stefan Schouten, Mart Krupovic, David Prangishvili, Edward H. Egelman
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Multidisciplinary Sciences
Alexis Huet, Robert L. Duda, Pascale Boulanger, James F. Conway
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Virology
Alexis Huet, Jamie B. Huffman, James F. Conway, Fred L. Homa
JOURNAL OF VIROLOGY
(2020)
Article
Multidisciplinary Sciences
Daniel J. Goetschius, Samantha R. Hartmann, Lindsey J. Organtini, Heather Callaway, Kai Huang, Carol M. Bator, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Colin R. Parrish, Susan L. Hafenstein
Summary: The study identified a significant overlap between the antigenic epitope and the receptor binding site of canine parvovirus, showing that specific antibody binding induces conformational changes to the virus. The findings highlight the potential of using cryo-EM to investigate complementarity of antibody binding.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Dapeng Sun, Zhe Sang, Yong Joon Kim, Yufei Xiang, Tomer Cohen, Anna K. Belford, Alexis Huet, James F. Conway, Ji Sun, Derek J. Taylor, Dina Schneidman-Duhovny, Cheng Zhang, Wei Huang, Yi Shi
Summary: Highly potent neutralizing nanobodies (Nbs) targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike protein show effectiveness against circulating variants of concern. Structural analysis of the Nbs provides insights into their high-affinity and broadly neutralizing activity against the virus.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Herman K. H. Fung, Shelley Grimes, Alexis Huet, Robert L. Duda, Maria Chechik, Joseph Gault, Carol Robinson, Roger W. Hendrix, Paul J. Jardine, James F. Conway, Christoph G. Baumann, Alfred A. Antson
Summary: Many cellular processes rely on substrate rotation or translocation by a multi-subunit, ring-type NTPase. Researchers have reconstituted a cos packaging system and provided a detailed description of its biochemical and structural properties, revealing similarities and differences in its mechanism and regulation.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Multidisciplinary Sciences
Alexis Huet, Bonnie Oh, Josh Maurer, Robert L. Duda, James F. Conway
Summary: Tailed bacteriophages and herpesviruses use a scaffold to assemble icosahedral capsids, with hexameric capsomers on the faces and pentameric capsomers at most vertices. The portal vertex structure of bacteriophage HK97 procapsid was determined, revealing a scaffold formed by the major capsid protein. The scaffold is organized into rigid helix-turn-strand structures on the capsomers and trimeric coiled-coil towers around the portal, explaining the coordination of assembly at this early step.