Histone variants on the move: substrates for chromatin dynamics

Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP

(2016) Aravind Basavapathruni et al.   BIOCHEMISTRY

ATRX binds to atypical chromatin domains at the 3′ exons of zinc finger genes to preserve H3K9me3 enrichment

(2016) David Valle-García et al.   Epigenetics

Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks

(2016) Ozge Gursoy-Yuzugullu et al.   JOURNAL OF MOLECULAR BIOLOGY

EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation

(2016) Suman K. Pradhan et al.   MOLECULAR CELL

On the origin and evolutionary consequences of gene body DNA methylation

(2016) Adam J. Bewick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly

(2016) Jiayi Yang et al.   Cell Reports

Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A

(2016) Naoki Horikoshi et al.   Open Biology

Constitutive turnover of histone H2A.Z at yeast promoters requires the preinitiation complex

(2016) Michael Tramantano et al.   eLife

Enhancer regions show high histone H3.3 turnover that changes during differentiation

(2016) Aimee M Deaton et al.   eLife

Fractal Characterization of Chromatin Decompaction in Live Cells

(2015) Ji Yi et al.   BIOPHYSICAL JOURNAL

Histone chaperones in Arabidopsis and rice: genome-wide identification, phylogeny, architecture and transcriptional regulation

(2015) Amit K Tripathi et al.   BMC PLANT BIOLOGY

Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline

(2015) Jing Xie et al.   CELL

The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation

(2015) Quanyuan He et al.   Cell Stem Cell

Diversity in the organization of centromeric chromatin

(2015) Florian A Steiner et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Atrx promotes heterochromatin formation at retrotransposons

(2015) D. Sadic et al.   EMBO REPORTS

Histone variants as emerging regulators of embryonic stem cell identity

(2015) Valentina Turinetto et al.   Epigenetics

Two distinct modes for propagation of histone PTMs across the cell cycle

(2015) Constance Alabert et al.   GENES & DEVELOPMENT

A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin

(2015) J. Peter Svensson et al.   GENOME RESEARCH

The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations

(2015) Célia Jeronimo et al.   MOLECULAR CELL

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

(2015) Slawomir Kubik et al.   MOLECULAR CELL

FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs

(2015) David J. Kemble et al.   MOLECULAR CELL

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

(2015) Simon J. Elsässer et al.   NATURE

The interplay between nucleoid organization and transcription in archaeal genomes

(2015) Eveline Peeters et al.   NATURE REVIEWS MICROBIOLOGY

The molecular basis for centromere identity and function

(2015) Kara L. McKinley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks

(2015) Hongda Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

(2015) Fiona T. M. Chang et al.   NUCLEIC ACIDS RESEARCH

Structural insight into how the human helicase subunit MCM2 may act as a histone chaperone together with ASF1 at the replication fork

(2015) Nicolas Richet et al.   NUCLEIC ACIDS RESEARCH

The histone chaperone complex HIR maintains nucleosome occupancy and counterbalances impaired histone deposition in CAF-1 complex mutants

(2015) Céline Duc et al.   PLANT JOURNAL

CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells

(2015) Rajbir K Athwal et al.   Epigenetics & Chromatin

A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks

(2015) Hongda Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes

(2015) Hsiao P.J. Voon et al.   Cell Reports

Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression

(2015) Matthieu D. Lavigne et al.   Cell Reports

Replicating nucleosomes

(2015) S. Ramachandran et al.   Science Advances

Histone Chaperones: Assisting Histone Traffic and Nucleosome Dynamics

(2014) Zachary A. Gurard-Levin et al.   Annual Review of Biochemistry

The Histone Variant H2A.W Defines Heterochromatin and Promotes Chromatin Condensation in Arabidopsis

(2014) Ramesh Yelagandula et al.   CELL

Asymmetric nucleosomes flank promoters in the budding yeast genome

(2014) Srinivas Ramachandran et al.   GENOME RESEARCH

Reorganization of Damaged Chromatin by the Exchange of Histone Variant H2A.Z-2

(2014) Ikuno Nishibuchi et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle

(2014) Ekaterina Boyarchuk et al.   JOURNAL OF CELL SCIENCE

The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer

(2014) Jingjun Hong et al.   MOLECULAR CELL

Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

(2014) Nicolas Lacoste et al.   MOLECULAR CELL

Nucleosomes Are Context-Specific, H2A.Z-Modulated Barriers to RNA Polymerase

(2014) Christopher M. Weber et al.   MOLECULAR CELL

ANP32E is a histone chaperone that removes H2A.Z from chromatin

(2014) Arnaud Obri et al.   NATURE

Identification of histone 3 variant 2 interacting factors

(2014) Daniel Latreille et al.   NUCLEIC ACIDS RESEARCH

Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units

(2014) F. Song et al.   SCIENCE

Selective Methylation of Histone H3 Variant H3.1 Regulates Heterochromatin Replication

(2014) Y. Jacob et al.   SCIENCE

Environmental responses mediated by histone variants

(2014) Paul B. Talbert et al.   TRENDS IN CELL BIOLOGY

Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2

(2013) Naoki Horikoshi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hira-Dependent Histone H3.3 Deposition Facilitates PRC2 Recruitment at Developmental Loci in ES Cells

(2013) Laura A. Banaszynski et al.   CELL

Nucleosome-free Region Dominates Histone Acetylation in Targeting SWR1 to Promoters for H2A.Z Replacement

(2013) Anand Ranjan et al.   CELL

Regulation of histone gene transcription in yeast

(2013) Christoph F. Kurat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone variants in pluripotency and disease

(2013) P. J. Skene et al.   DEVELOPMENT

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin

(2013) P. Chen et al.   GENES & DEVELOPMENT

Subfunctionalization via Adaptive Evolution Influenced by Genomic Context: The Case of Histone Chaperones ASF1a and ASF1b

(2013) Federico Abascal et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural basis of histone H2A–H2B recognition by the essential chaperone FACT

(2013) Maria Hondele et al.   NATURE

Histone chaperone FACT action during transcription through chromatin by RNA polymerase II

(2013) F.-K. Hsieh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental roles of histone H3 variants and their chaperones

(2013) Dan Filipescu et al.   TRENDS IN GENETICS

Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3

(2013) Hiroaki Kato et al.   Scientific Reports

Eukaryotic Replisome Components Cooperate to Process Histones During Chromosome Replication

(2013) Magdalena Foltman et al.   Cell Reports

TIP48/Reptin and H2A.Z Requirement for Initiating Chromatin Remodeling in Estrogen-Activated Transcription

(2013) Mathieu Dalvai et al.   PLoS Genetics

H3.3-H4 Tetramer Splitting Events Feature Cell-Type Specific Enhancers

(2013) Chang Huang et al.   PLoS Genetics

Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3

(2013) Daniel C Kraushaar et al.   GENOME BIOLOGY

Architectural organization in E. coli nucleoid

(2012) Mirjana Macvanin et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

ATRX-mediated chromatin association of histone variant macroH2A1 regulates  -globin expression

(2012) K. Ratnakumar et al.   GENES & DEVELOPMENT

DAXX-dependent supply of soluble (H3.3-H4) dimers to PML bodies pending deposition into chromatin

(2012) E. Delbarre et al.   GENOME RESEARCH

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

(2012) Simon J. Elsässer et al.   NATURE

Genome-wide structure and organization of eukaryotic pre-initiation complexes

(2012) Ho Sung Rhee et al.   NATURE

Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics

(2012) Maxim Nekrasov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization

(2012) Clemens Bönisch et al.   NUCLEIC ACIDS RESEARCH

Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition

(2012) Duane D. Winkler et al.   NUCLEIC ACIDS RESEARCH

CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA

(2012) Wallace H. Liu et al.   NUCLEIC ACIDS RESEARCH

Nucleosome-depleted chromatin gaps recruit assembly factors for the H3.3 histone variant

(2012) J. I. Schneiderman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana

(2012) H. Stroud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric Division of Drosophila Male Germline Stem Cell Shows Asymmetric Histone Distribution

(2012) V. Tran et al.   SCIENCE

Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3 Lysine 27 Methylation

(2012) W. Yuan et al.   SCIENCE

Dynamic Deposition of Histone Variant H3.3 Accompanies Developmental Remodeling of the Arabidopsis Transcriptome

(2012) Heike Wollmann et al.   PLoS Genetics

Deposition of Histone Variant H2A.Z within Gene Bodies Regulates Responsive Genes

(2012) Devin Coleman-Derr et al.   PLoS Genetics

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

A model for mitotic inheritance of histone lysine methylation

(2011) Mo Xu et al.   EMBO REPORTS

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

(2011) Arunkumar Dhayalan et al.   HUMAN MOLECULAR GENETICS

Sequential Establishment of Marks on Soluble Histones H3 and H4

(2011) Francisca Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity

(2011) Dominique Ray-Gallet et al.   MOLECULAR CELL

Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin

(2011) Sebastian Eustermann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A unique H2A histone variant occupies the transcriptional start site of active genes

(2011) Tatiana A Soboleva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

(2010) L. H. Wong et al.   GENOME RESEARCH

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

H2A.Z nucleosomes enriched over active genes are homotypic

(2010) Christopher M Weber et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The program for processing newly synthesized histones H3.1 and H4

(2010) Eric I Campos et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of chromatin remodeling

(2010) Yahli Lorch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partitioning of Histone H3-H4 Tetramers During DNA Replication-Dependent Chromatin Assembly

(2010) M. Xu et al.   SCIENCE

Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones

(2010) R. B. Deal et al.   SCIENCE

The histone methyltransferase SUV420H2 and Heterochromatin Proteins HP1 interact but show different dynamic behaviours

(2009) Patricia P Souza et al.   BMC CELL BIOLOGY

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues

(2009) José M Eirín-López et al.   BMC EVOLUTIONARY BIOLOGY

Mechanisms that Specify Promoter Nucleosome Location and Identity

(2009) Paul D. Hartley et al.   CELL

H2A.Z-Containing Nucleosomes Mediate the Thermosensory Response in Arabidopsis

(2009) S. Vinod Kumar et al.   CELL

Transcriptional and Developmental Functions of the H3.3 Histone Variant in Drosophila

(2009) Akiko Sakai et al.   CURRENT BIOLOGY

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Histone Chaperone Spt16 Promotes Redeposition of the Original H3-H4 Histones Evicted by Elongating RNA Polymerase

(2009) Adil Jamai et al.   MOLECULAR CELL

yFACT Induces Global Accessibility of Nucleosomal DNA without H2A-H2B Displacement

(2009) Hua Xin et al.   MOLECULAR CELL

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

The γ-H2A.X: Is it just a surrogate marker of double-strand breaks or much more?

(2007) Ismail Hassan Ismail et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS