Recent Advancement in the Synthesis of Ir-Based Complexes

In Vitro and In Vivo Antitumor Assay of Mitochondrially Targeted Fluorescent Half-Sandwich Iridium(III) Pyridine Complexes

(2023) Liyan Wang et al.   Inorganic Chemistry

Design, synthesis and biological evaluation of liposome entrapped iridium(III) complexes toward SGC-7901 cells

(2023) Yichuan Chen et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Design and synthesis of aptamer-cyclometalated iridium(III) complex conjugate targeting cancer cells

(2022) Weigang Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents

(2022) Yuting Wu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Anticancer effect evaluation of iridium(III) complexes targeting mitochondria and endoplasmic reticulum

(2022) Yi Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Iridium (III) complexes induce cervical carcinoma apoptosis via disturbing cellular redox homeostasis disorder and inhibiting PI3K/AKT/mTOR pathway

(2022) Jing Hao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Current status of iridium-based complexes against lung cancer

(2022) Tongfu Yang et al.   Frontiers in Pharmacology

Synthesis, biological evaluation of novel iridium(III) complexes targeting mitochondria toward melanoma B16 cells

(2022) Yuhan Yuan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and biological evaluation of two cyclometalated iridium(III) complexes containing a glutathione S-transferase inhibitor

(2022) Jian Zhao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay

(2022) Jinfeng Liu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Studies of anticancer activity in vivo and in vitro behaviors of liposomes encapsulated iridium(III) complex

(2021) Yiying Gu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Bioactive half-sandwich Rh and Ir bipyridyl complexes containing artemisinin

(2021) Prinessa Chellan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Phosphorogenic dipyrrinato-iridium(III) complexes as photosensitizers for photodynamic therapy

(2021) A. Prieto-Castañeda et al.   DYES AND PIGMENTS

Mitochondria-targeted phosphorescent cyclometalated iridium(III) complexes: synthesis, characterization, and anticancer properties

(2020) Yi Li et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Iridium(Ⅲ) complex-based phosphorescent probe for rapid, specific, and sensitive detection of phosgene

(2020) Bin Ma et al.   DYES AND PIGMENTS

Anticancer Cyclometalated Iridium(III) Complexes with Planar Ligands: Mitochondrial DNA Damage and Metabolism Disturbance

(2019) Jian-Jun Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents

(2019) Juran Kralj et al.   ORGANOMETALLICS

Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes

(2019) Yi Li et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The side effects of platinum-based chemotherapy drugs: a review for chemists

(2018) Rabbab Oun et al.   DALTON TRANSACTIONS

Cyclometalated iridium(iii) complexes induce mitochondria-derived paraptotic cell death and inhibit tumor growth in vivo

(2018) Liang He et al.   DALTON TRANSACTIONS

Synthesis and in vitro biological evaluation of three 4′-(4-methoxyphenyl)-2,2′:6′,2″-terpyridine iridium(III) complexes as new telomerase inhibitors

(2018) Qi-Pin Qin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An iridium (III) complex as potent anticancer agent induces apoptosis and autophagy in B16 cells through inhibition of the AKT/mTOR pathway

(2018) Bing Tang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and anticancer activity in vitro and in vivo evaluation of an iridium (III) polypyridyl complex

(2018) Qiao-Yan Yi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel iridium(III) iminopyridine complexes: synthetic, catalytic, and in vitro anticancer activity studies

(2018) Deliang Kong et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Half-sandwich complexes of platinum group metals (Ir, Rh, Ru and Os) and some recent biological and catalytic applications

(2018) Joel M. Gichumbi et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Tracking mitochondrial dynamics during apoptosis with phosphorescent fluorinated iridium(iii) complexes

(2018) Chen Zhang et al.   DALTON TRANSACTIONS

Novel and Versatile Imine-N-Heterocyclic Carbene Half-Sandwich Iridium(III) Complexes as Lysosome-Targeted Anticancer Agents

(2018) Yuliang Yang et al.   INORGANIC CHEMISTRY

Half-sandwich IridiumIII N-heterocyclic carbene antitumor complexes and biological applications

(2018) Yali Han et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Half-Sandwich Iridium and Ruthenium Complexes: Effective Tracking in Cells and Anticancer Studies

(2018) JuanJuan Li et al.   INORGANIC CHEMISTRY

Fluorescent half-sandwich phosphine-sulfonate iridium(III) and ruthenium(II) complexes as potential lysosome-targeted anticancer agents

(2018) Qing Du et al.   DYES AND PIGMENTS

Novel lysosome-targeted cyclometalated Iridium(III) anticancer complexes containing imine-N-heterocyclic carbene ligands: Synthesis, spectroscopic properties and biological activity

(2018) Yuliang Yang et al.   DYES AND PIGMENTS

“Half-sandwich” Schiff-base Ir(III) complexes as anticancer agents

(2017) Ze-dong Mou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium(iii) complexes

(2017) Jian-Jun Cao et al.   Chemical Science

Real-time tracking mitochondrial dynamic remodeling with two-photon phosphorescent iridium (III) complexes

(2016) Huaiyi Huang et al.   BIOMATERIALS

Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents

(2015) Yi Li et al.   BIOMATERIALS

Cyclometalated iridium(iii) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents

(2015) Liang He et al.   Chemical Science

Mitochondria-specific imaging and tracking in living cells with two-photon phosphorescent iridium(iii) complexes

(2015) Kangqiang Qiu et al.   Journal of Materials Chemistry B

Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

(2014) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Heteroleptic Cyclometalated Iridium(III) Complexes Supported by Triarylborylpicolinate Ligand: Ratiometric Turn-On Phosphorescence Response upon Fluoride Binding

(2014) Sanjeev Sharma et al.   INORGANIC CHEMISTRY

Charged Bis-Cyclometalated Iridium(III) Complexes with Carbene-Based Ancillary Ligands

(2013) Filippo Monti et al.   INORGANIC CHEMISTRY

Novel C,N-chelate rhodium(iii) and iridium(iii) antitumor complexes incorporating a lipophilic steroidal conjugate and their interaction with DNA

(2012) José Ruiz et al.   DALTON TRANSACTIONS

Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

(2012) Stephanie J. Lucas et al.   DALTON TRANSACTIONS

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Half-Sandwich Iridium Complexes for Homogeneous Water-Oxidation Catalysis

(2010) James D. Blakemore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Half-sandwich iridium complexes—Synthesis and applications in catalysis

(2008) Jianke Liu et al.   COORDINATION CHEMISTRY REVIEWS