Article
Multidisciplinary Sciences
Aysun Firat, Aysegul Ercan, Cengiz Mordeniz, Fatma Ferda Verit Atmaca
Summary: This study aimed to investigate whether the pretreatment hemogram parameters and their ratios can predict the endometrial transformation in patients with abnormal uterine bleeding. The study found that age, postmenopausal state, obesity, diabetes, and increased estrogen exposure were risk factors for endometrial atypia and carcinoma. Hemoglobin and hematocrit levels were significantly higher in early and advanced endometrial cancer groups, while platelet value was significantly higher in atypia and carcinoma groups.
Article
Oncology
Mengli Zhao, Zhongrong Gao, Xiaowei Gu, Xiaojing Yang, Shanshan Wang, Jie Fu
Summary: The research focuses on analyzing the prognostic significance of minimum count of lymphocytes (LY) and the corresponding ratio of neutrophil-to-lymphocyte (NLR) in cervical cancer patients receiving radiotherapy. The study found that patients with higher LY levels and lower NLR values during radiotherapy had better survival prognosis. Factors such as FIGO stage I, absence of lymph node metastasis, and lower NLR values were associated with poorer overall survival and progression-free survival.
Article
Endocrinology & Metabolism
Peng Ning, Fan Yang, Jun Kang, Jing Yang, Jiaxing Zhang, Yi Tang, Yanghong Ou, Haiyan Wan, Hongyi Cao
Summary: This study found that platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) were associated with arterial stiffness in patients with diabetes. Among them, NLR showed higher accuracy in predicting arterial stiffness.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Tan Xie, Dongliang Hou, Jiaxiang Wang, Song Zhao
Summary: This study showed that elevated NLR and PLR were poor prognostic factors in hepatoblastoma patients before treatment, and NLR was an independent prognostic factor for overall survival.
FRONTIERS IN PEDIATRICS
(2023)
Review
Multidisciplinary Sciences
Benshu Qian, Yue Zheng, Huimiao Jia, Xi Zheng, Rongyue Gao, Wenxiong Li
Summary: The objective of this study was to evaluate the accuracy of the neutrophil-lymphocyte ratio in predicting postoperative infection. The meta-analysis of 12 studies showed that the neutrophil-lymphocyte ratio has a certain predictive value for postoperative infection.
Article
Multidisciplinary Sciences
Tetsuya Akaishi, Tatsuro Misu, Kazuo Fujihara, Naoki Nakaya, Tomohiro Nakamura, Mana Kogure, Rieko Hatanaka, Fumi Itabashi, Ikumi Kanno, Toshiyuki Takahashi, Hiroshi Kuroda, Juichi Fujimori, Yoshiki Takai, Shuhei Nishiyama, Kimihiko Kaneko, Tadashi Ishii, Masashi Aoki, Ichiro Nakashima, Atsushi Hozawa
Summary: Patients with multiple sclerosis showed elevated counts of total white blood cells, monocytes, basophils, and neutrophils at the time of diagnosis. However, the clinical relevance of these biomarkers in the context of the development and progression of MS remains unclear.
SCIENTIFIC REPORTS
(2021)
Article
Orthopedics
H. Xu, J-W Xie, L. Liu, D. Wang, Z-Y Huang, Z-K Zhou
Summary: MLR and NLR have diagnostic value for screening FRI in patients undergoing conversion THA after failed internal fixation for femoral neck fracture, while the combination of CRP with NLR shows high sensitivity and specificity for screening FRI in these patients.
BONE & JOINT JOURNAL
(2021)
Article
Clinical Neurology
Oguz Oren, Cemile Haki, Halil Kaya, Melih Yuksel
Summary: This study aimed to investigate whether the baseline neutrophil/lymphocyte ratio (NLR) predicts symptomatic intracranial hemorrhage (SICH) due to intravenous thrombolytic therapy. However, the results showed that NLR did not provide strong specificity and sensitivity for predicting SICH, and a precise cut-off value could not be found to predict hemorrhagic transformation.
NEUROLOGICAL SCIENCES
(2022)
Review
Oncology
Tibera K. Rugambwa, Omar Abdihamid, Xiangyang Zhang, Yinghui Peng, Changjing Cai, Hong Shen, Shan Zeng, Wei Qiu
Summary: This study aimed to investigate the correlation between neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) and the treatment outcomes of immune checkpoint inhibitors (ICIs). The results showed that patients with lower NLR and PLR were more likely to achieve clinical benefit and better treatment response, while higher NLR and PLR were associated with poorer treatment outcomes.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medical Laboratory Technology
Dan Liu, Xinyan Huang, Zhengxian Xu, Minzhi Chen, Manyu Wu
Summary: The predictive value of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in missed miscarriage was investigated in this study. The results showed that NLR and PLR were not suitable indicators for missed miscarriage, but attention should be paid to mean platelet volume (MPV) in the first trimester.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Article
Oncology
Wentao Wang, Yilin Tong, Shulan Sun, Yuen Tan, Zexing Shan, Fan Sun, Chengyao Jiang, Yanmei Zhu, Jianjun Zhang
Summary: This study found that pretreatment neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) can independently predict tumor regression grade (TRG) after neoadjuvant chemotherapy in patients with locally advanced gastric cancer. Patients with high NLR and PLR values may benefit from alternative treatments.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Shihai Yang, Shangdong Li
Summary: This study aimed to establish a predictive model using neutrophil-lymphocyte ratio (NLR) to predict the survival prognosis of patients with gastric signet ring cell carcinoma (GSRC). The results showed that patients with NLR < 2.8 had significantly better overall survival and tumor recurrence rates compared to those with NLR > 2.8. After adjusting for other risk factors, NLR < 2.8, tumor size, and tumor metastasis remained independent predictors of tumor recurrence rate and overall survival. The study confirmed the value of NLR in predicting the prognosis of GSRC patients.
Article
Orthopedics
Daniel Timothy Burchette, Mustafa Fatih Dasci, Beatriz Fernandez Maza, Philip Linke, Thorsten Gehrke, Mustafa Citak
Summary: This study aims to investigate the correlation between Neutrophil-to-Lymphocyte (NLR) and Lymphocyte-to-Monocyte (LMR) ratios and their value in the diagnosis of chronic prosthetic joint infection, and evaluate their diagnostic value.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Pharmacology & Pharmacy
B. Yesil, A. R. Caliskan, K. Kosar, M. Yuksel, H. Gokcan, A. Tumturk, H. T. Koseoglu, M. Akdogan Kayhan
Summary: This study revealed a significant correlation between the severity of acute cholangitis and the degree of lymphocytopenia, NLR, and PLR. As the severity of the disease increased, the proportion of patients with normal lymphocyte count decreased, while abnormal findings and NLR and PLR levels increased.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Psychiatry
Li Nie, Xian-li Pan, Xiao-bao Zhang, Shan Zhang, Ji-Xian Rao, Zeng-feng Su
Summary: Patients with chronic insomnia have immunological abnormalities, characterized by a higher incidence of clinical infection.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Ji Yeon Lim, Duk Hee Lee
JOURNAL OF KOREAN MEDICAL SCIENCE
(2018)
Article
Medicine, Legal
Ji Yeon Lim, Koo Young Jung, Duk Hee Lee, Kyung-moo Yang, Minsung Choi, Jong-Pil Park, Jae Hee Lee
JOURNAL OF FORENSIC AND LEGAL MEDICINE
(2020)
Article
Environmental Sciences
Soon Young Yun, Ji Yeon Lim, Eun Kim, Jongseok Oh, Duk Hee Lee
Summary: The South Korean population is aging rapidly, leading to an increase in the number of older patients being transferred from long-term-care hospitals (LTCHs) to emergency departments (EDs). This retrospective study analyzed data from 2014 to 2019 to investigate the epidemiology, characteristics, and clinical outcomes of these older patients. The findings showed that a significant proportion of patients from LTCHs were discharged from EDs, while others returned to the LTCHs, with longer ED stays for those returning to LTCHs.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)