F-actin dismantling through a redox-driven synergy between Mical and cofilin

Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains

(2016) Teresa Vitali et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover

(2016) Samantha M. Chin et al.   JOURNAL OF MOLECULAR BIOLOGY

Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights

(2016) Saif S. Alqassim et al.   Scientific Reports

Viral Semaphorin Inhibits Dendritic Cell Phagocytosis and Migration but Is Not Essential for Gammaherpesvirus-Induced Lymphoproliferation in Malignant Catarrhal Fever

(2015) Françoise Myster et al.   JOURNAL OF VIROLOGY

Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage

(2015) Sheng Tao Hou et al.   Scientific Reports

Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy

(2015) Kien Xuan Ngo et al.   eLife

Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling

(2014) Mark R. Lundquist et al.   CELL

Seamless Tube Shape Is Constrained by Endocytosis-Dependent Regulation of Active Moesin

(2014) Jodi Schottenfeld-Roames et al.   CURRENT BIOLOGY

INF2-Mediated Severing through Actin Filament Encirclement and Disruption

(2014) Pinar S. Gurel et al.   CURRENT BIOLOGY

Drebrin inhibits cofilin-induced severing of F-actin

(2014) Elena E. Grintsevich et al.   Cytoskeleton

Semaphorin3a Promotes Advanced Diabetic Nephropathy

(2014) Pardeep K. Aggarwal et al.   DIABETES

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

(2014) Eljo Y. Van Battum et al.   Nature Communications

MICAL-Family Proteins: Complex Regulators of the Actin Cytoskeleton

(2013) Sai Srinivas Panapakkam Giridharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Actin Stimulates Reduction of the MICAL-2 Monooxygenase Domain

(2013) Claudia A. McDonald et al.   BIOCHEMISTRY

MICAL, the Flavoenzyme Participating in Cytoskeleton Dynamics

(2013) Maria Vanoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of actin disassembly

(2013) William Brieher   MOLECULAR BIOLOGY OF THE CELL

MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation

(2013) Byung Cheon Lee et al.   MOLECULAR CELL

SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

(2013) Ruei-Jiun Hung et al.   NATURE CELL BIOLOGY

Functions of cofilin in cell locomotion and invasion

(2013) Jose Javier Bravo-Cordero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function

(2012) Deborah A. Witherden et al.   IMMUNITY

Drosophila Psidin Regulates Olfactory Neuron Number and Axon Targeting through Two Distinct Molecular Mechanisms

(2012) D. Stephan et al.   JOURNAL OF NEUROSCIENCE

14-3-3ε Couples Protein Kinase A to Semaphorin Signaling and Silences Plexin RasGAP-Mediated Axonal Repulsion

(2012) Taehong Yang et al.   NEURON

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

(2011) Daniela Zucchini et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cofilin-Linked Changes in Actin Filament Flexibility Promote Severing

(2011) Brannon R. McCullough et al.   BIOPHYSICAL JOURNAL

MICALs in control of the cytoskeleton, exocytosis, and cell death

(2011) Yeping Zhou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cofilin Tunes the Nucleotide State of Actin Filaments and Severs at Bare and Decorated Segment Boundaries

(2011) Cristian Suarez et al.   CURRENT BIOLOGY

Actin dynamics and turnover in cell motility

(2011) Klemens Rottner et al.   CURRENT OPINION IN CELL BIOLOGY

Remodeling of actin filaments by ADF/cofilin proteins

(2011) V. E. Galkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Antiparallel Dimer and Actin Assembly

(2010) Elena E. Grintsevich et al.   BIOCHEMISTRY

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Signaling from Axon Guidance Receptors

(2010) G. J. Bashaw et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms and Molecules of Neuronal Wiring: A Primer

(2010) A. L. Kolodkin et al.   Cold Spring Harbor Perspectives in Biology

A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning

(2009) Daniel Kirilly et al.   NATURE NEUROSCIENCE

Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration

(2009) H. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ins and outs of ADF/cofilin activity and regulation

(2008) M VANTROYS et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

TheDrosophilaCD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning

(2008) Ruth I. Johnson et al.   JOURNAL OF CELL BIOLOGY

Mapping the Cofilin Binding Site on Yeast G-Actin by Chemical Cross-Linking

(2008) Elena E. Grintsevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Release of MICAL Autoinhibition by Semaphorin-Plexin Signaling Promotes Interaction with Collapsin Response Mediator Protein

(2008) E. F. Schmidt et al.   JOURNAL OF NEUROSCIENCE