iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

(2016) Jennifer Davis et al.   CELL

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

(2016) Paul W Burridge et al.   NATURE MEDICINE

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine

(2016) Elena Matsa et al.   PHYSIOLOGICAL REVIEWS

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy

(2015) Haodi Wu et al.   Cell Stem Cell

Sequential Notch activation regulates ventricular chamber development

(2015) Gaetano D’Amato et al.   NATURE CELL BIOLOGY

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

(2015) J. T. Hinson et al.   SCIENCE

Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-mediated regeneration

(2014) Wen-Pin Chen et al.   CARDIOVASCULAR RESEARCH

Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing

(2014) Yongming Wang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chemically defined generation of human cardiomyocytes

(2014) Paul W Burridge et al.   NATURE METHODS

Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of PRDM16 as a Cause of Cardiomyopathy

(2013) Anne-Karin Arndt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sources of bias in measures of allele-specific expression derived from RNA-seq data aligned to a single reference genome

(2013) Kraig R Stevenson et al.   BMC GENOMICS

Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells

(2013) Feng Lan et al.   Cell Stem Cell

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

(2013) Guillermo Luxán et al.   NATURE MEDICINE

Seamless genome editing in human pluripotent stem cells using custom endonuclease–based gene targeting and the piggyBac transposon

(2013) Kosuke Yusa   Nature Protocols

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models

(2012) Qiurong Ding et al.   Cell Stem Cell

14-3-3ε Gene variants in a Japanese patient with left ventricular noncompaction and hypoplasia of the corpus callosum

(2012) Bo Chang et al.   GENE

Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function

(2012) Noboru J. Sakabe et al.   HUMAN MOLECULAR GENETICS

14-3-3  Plays a Role in Cardiac Ventricular Compaction by Regulating the Cardiomyocyte Cell Cycle

(2012) Y. Kosaka et al.   MOLECULAR AND CELLULAR BIOLOGY

Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy

(2012) N. Sun et al.   Science Translational Medicine

Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo

(2011) Santanu Chakraborty et al.   DEVELOPMENTAL BIOLOGY

Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?

(2011) E. Oechslin et al.   EUROPEAN HEART JOURNAL

Pharmacologic Inhibition of ALK5 Causes Selective Induction of Terminal Differentiation in Mouse Keratinocytes Expressing Oncogenic HRAS

(2011) L. M. Markell et al.   MOLECULAR CANCER RESEARCH

Modelling the long QT syndrome with induced pluripotent stem cells

(2011) Ilanit Itzhaki et al.   NATURE

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Conditional overexpression of TGF-β1 disrupts mouse salivary gland development and function

(2010) Bradford E Hall et al.   LABORATORY INVESTIGATION

Transient Expression of FRNK Reveals Stage-Specific Requirement for Focal Adhesion Kinase Activity in Cardiac Growth

(2009) Laura A. DiMichele et al.   CIRCULATION RESEARCH

Prdm16 is required for normal palatogenesis in mice

(2009) Bryan C. Bjork et al.   HUMAN MOLECULAR GENETICS

A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects

(2009) M. G. Posch et al.   JOURNAL OF MEDICAL GENETICS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

(2009) K. Kodo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Left ventricular noncompaction and cardiomyopathy: cause, contributor, or epiphenomenon?

(2008) Srijita Sen-Chowdhry et al.   CURRENT OPINION IN CARDIOLOGY

T-box transcription factor TBX20 mutations in Chinese patients with congenital heart disease

(2008) Caixia Liu et al.   European Journal of Medical Genetics

Smad7 Is Required for the Development and Function of the Heart

(2008) Qian Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SKI and MEL1 Cooperate to Inhibit Transforming Growth Factor-β Signal in Gastric Cancer Cells

(2008) Mami Takahata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of TBX20 in human hearts and its regulation by TFAP2

(2008) Stefanie Hammer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease

(2008) L. Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA