Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

Quantification of cell viability and rapid screening anti-cancer drug utilizing nanomechanical fluctuation

(2016) Shangquan Wu et al.   BIOSENSORS & BIOELECTRONICS

Characterizing Cellular Biophysical Responses to Stress by Relating Density, Deformability, and Size

(2015) Sangwon Byun et al.   BIOPHYSICAL JOURNAL

Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy

(2015) Joan Montero et al.   CELL

Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia

(2015) M. Andreeff et al.   CLINICAL CANCER RESEARCH

Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas

(2015) M. Verreault et al.   CLINICAL CANCER RESEARCH

An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors

(2015) Oliver Jonas et al.   Science Translational Medicine

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

(2014) Andrew A Lane et al.   NATURE GENETICS

Patient-derived models of acquired resistance can identify effective drug combinations for cancer

(2014) Adam S. Crystal et al.   SCIENCE

EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing

(2014) J. M. Francis et al.   Cancer Discovery

Genomic impact of transient low-dose decitabine treatment on primary AML cells

(2013) J. M. Klco et al.   BLOOD

Inconsistency in large pharmacogenomic studies

(2013) Benjamin Haibe-Kains et al.   NATURE

What a Tangled Web We Weave: Emerging Resistance Mechanisms to Inhibition of the Phosphoinositide 3-Kinase Pathway

(2013) S. J. Klempner et al.   Cancer Discovery

Direct observation of mammalian cell growth and size regulation

(2012) Sungmin Son et al.   NATURE METHODS

Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias

(2012) Jorge E. Cortes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circumventing Cancer Drug Resistance in the Era of Personalized Medicine

(2012) Levi A. Garraway et al.   Cancer Discovery

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Evidence for label-retaining tumour-initiating cells in human glioblastoma

(2011) Loic P. Deleyrolle et al.   BRAIN

American Society of Clinical Oncology Clinical Practice Guideline Update on the Use of Chemotherapy Sensitivity and Resistance Assays

(2011) Harold J. Burstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells

(2011) Justin D. Lathia et al.   PLoS One

Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3

(2010) Thomas Fischer et al.   JOURNAL OF CLINICAL ONCOLOGY

Using buoyant mass to measure the growth of single cells

(2010) Michel Godin et al.   NATURE METHODS

Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

(2009) Martin L. Sos et al.   JOURNAL OF CLINICAL INVESTIGATION