Cognitive Functions, Neurotransmitter Alterations, and Hippocampal Microstructural Changes in Mice Caused by Feeding on Western Diet

Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model

(2023) Raly James Perez Custodio et al.   Communications Biology

Segregation of D1 and D2 dopamine receptors in the striatal direct and indirect pathways: An historical perspective

(2023) Charles R. Gerfen   Frontiers in Synaptic Neuroscience

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression

(2023) Leandro Val Sayson et al.   Frontiers in Pharmacology

Comparative analysis between Open Field and Elevated Plus Maze tests as a method for evaluating anxiety-like behavior in mice

(2023) Mariah Mesquita de Figueiredo Cerqueira et al.   Heliyon

Age and an obesogenic diet affect mouse behaviour in a sex‐dependent manner

(2023) Emily J. Mort et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Reliable Method Based on Liquid Chromatography–Tandem Mass Spectrometry for the Simultaneous Quantification of Neurotransmitters in Caenorhabditis elegans

(2023) Ann-Kathrin Weishaupt et al.   MOLECULES

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

(2022) Ahmed Ghallab et al.   JOURNAL OF HEPATOLOGY

Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolism

(2022) Daniel E. Radford-Smith et al.   PLoS One

How to account for hallucinations in the interpretation of the antidepressant effects of psychedelics: a translational framework

(2022) Manon van den Berg et al.   PSYCHOPHARMACOLOGY

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity

(2022) Reham Hassan et al.   ARCHIVES OF TOXICOLOGY

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A

(2022) Reham Hassan et al.   ARCHIVES OF TOXICOLOGY

A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation

(2022) Wouter Claeys et al.   Scientific Reports

Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats

(2021) Parker Knight et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Propranolol-induced hallucinations mimicking encephalopathy in a patient with liver cirrhosis

(2021) Samer Al-Dury et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

R (−)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine

(2021) Chrislean Jun Botanas et al.   NEUROPHARMACOLOGY

Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria

(2021) Kathrin Gianmoena et al.   Cell Reports

Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression

(2021) Ahmed Ghallab et al.   Cells

Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein

(2021) Raly James Perez Custodio et al.   Communications Biology

Short-term high-fat diet favors the appearances of apoptosis and gliosis by activation of ERK1/2/p38MAPK pathways in brain

(2021) Chao-Jin Xu et al.   Aging-US

Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer’s Disease

(2021) Grzegorz A. Czapski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease

(2021) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

The menace of obesity to depression and anxiety prevalence

(2021) Stephanie Fulton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Gut Microbiome, Inflammation, and Cerebrovascular Function: Link Between Obesity and Cognition

(2021) Lisette Olsthoorn et al.   Frontiers in Neuroscience

Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics

(2020) Kendra J. Adams et al.   JOURNAL OF PROTEOME RESEARCH

Maturational delay and asymmetric information flow of brain connectivity in SHR model of ADHD revealed by topological analysis of metabolic networks

(2020) Seunggyun Ha et al.   Scientific Reports

Depression and Cognitive Impairment—Extrahepatic Manifestations of NAFLD and NASH

(2020) Martina Colognesi et al.   Biomedicines

Non-alcoholic fatty liver disease (NAFLD) as a neglected metabolic companion of psychiatric disorders: common pathways and future approaches

(2020) Óscar Soto-Angona et al.   BMC Medicine

Acquired hepatocerebral degeneration and hepatic encephalopathy: one or two entities?

(2020) M. J. Malaquias et al.   EUROPEAN JOURNAL OF NEUROLOGY

Affective Immunology: The Crosstalk Between Microglia and Astrocytes Plays Key Role?

(2020) Linglin Yang et al.   Frontiers in Immunology

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

(2019) Blanca Lizarbe et al.   Frontiers in Neuroscience

Transition from metabolically benign to metabolically unhealthy obesity and 10-year cardiovascular disease incidence: The ATTICA cohort study

(2019) Matina Kouvari et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe

(2019) Jeffrey V. Lazarus et al.   JOURNAL OF HEPATOLOGY

Neurobehavioral dysfunction in non-alcoholic steatohepatitis is associated with hyperammonemia, gut dysbiosis, and metabolic and functional brain regional deficits

(2019) Sara G. Higarza et al.   PLoS One

25B‐NBOMe, a novel N ‐2‐methoxybenzyl‐phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential

(2019) Raly James Perez Custodio et al.   ADDICTION BIOLOGY

Cytokines in Inflammatory Disease

(2019) Shinwan Kany et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Influence of Liver Fibrosis on Lobular Zonation

(2019) Ahmed Ghallab et al.   Cells

Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030

(2018) Chris Estes et al.   JOURNAL OF HEPATOLOGY

Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice

(2018) Raly James Perez Custodio et al.   NEUROSCIENCE

Dopamine: Functions, Signaling, and Association with Neurological Diseases

(2018) Marianne O. Klein et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Atxn7-overexpressing mice showed hyperactivity and impulsivity which were ameliorated by atomoxetine treatment: A possible animal model of the hyperactive-impulsive phenotype of ADHD

(2018) Irene Joy I. dela Peña et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure

(2018) Guoxiang Xie et al.   EBioMedicine

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

(2017) Arne Schenk et al.   Scientific Reports

Glial influences on BBB functions and molecular players in immune cell trafficking

(2016) Marc-André Lécuyer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer.

(2016) Jens Geginat et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

(2016) Ahmed Ghallab et al.   JOURNAL OF HEPATOLOGY

Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia

(2016) Vicente Hernandez-Rabaza et al.   Journal of Neuroinflammation

Maternal obesity and neurodevelopmental and psychiatric disorders in offspring

(2016) Andrea G. Edlow   PRENATAL DIAGNOSIS

Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory

(2016) Kimberly A. Kempadoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

(2016) Leah C. Graham et al.   Scientific Reports

Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners

(2015) Yunfeng Duan et al.   BEHAVIOURAL NEUROLOGY

Dopamine Directly Modulates GABAA Receptors

(2015) P. Hoerbelt et al.   JOURNAL OF NEUROSCIENCE

Refining the Ammonia Hypothesis

(2015) Elliot B. Tapper et al.   MAYO CLINIC PROCEEDINGS

Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase

(2015) Natalia Qvartskhava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment

(2015) E. Smith et al.   Obesity Reviews

Glutamate as a neurotransmitter in the healthy brain

(2014) Y. Zhou et al.   JOURNAL OF NEURAL TRANSMISSION

Low-grade chronic inflammation induces behavioral stereotypy in rats

(2014) Oytun Erbaş et al.   METABOLIC BRAIN DISEASE

Characterization of the head-twitch response induced by hallucinogens in mice

(2013) Adam L. Halberstadt et al.   PSYCHOPHARMACOLOGY

Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis

(2011) Annalisa Berzigotti et al.   HEPATOLOGY

Risk-Taking Behaviors of Adolescents With Extreme Obesity: Normative or Not?

(2011) M. B. Ratcliff et al.   PEDIATRICS

Do rats really express neophobia towards novel objects? Experimental evidence from exposure to novelty and to an object recognition task in an open space and an enclosed space

(2008) A. Ennaceur et al.   BEHAVIOURAL BRAIN RESEARCH