Tumor-targeted metabolic inhibitor prodrug labelled with cyanine dyes enhances immunoprevention of lung cancer

Photouncaging of Carboxylic Acids from Cyanine Dyes with Near‐Infrared Light**

(2022) Hana Janeková et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Harnessing Radical‐Mediated Photocaged Cyanine under Hypoxia for in vivo Precision Drug Release

(2021) Yutao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell-programmed nutrient partitioning in the tumour microenvironment

(2021) Bradley I. Reinfeld et al.   NATURE

Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

(2021) Jing Shi et al.   Acta Pharmaceutica Sinica B

Targeting cancer metabolism in the era of precision oncology

(2021) Zachary E. Stine et al.   NATURE REVIEWS DRUG DISCOVERY

Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma

(2021) Danyu Du et al.   Acta Pharmaceutica Sinica B

Electromagnetic nanomedicines for combinational cancer immunotherapy

(2020) Kanyi Pu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs

(2019) Lukáš Tenora et al.   JOURNAL OF MEDICINAL CHEMISTRY

We're Not “DON” Yet: Optimal Dosing and Prodrug Delivery of6-Diazo-5-oxo-L-norleucine

(2018) Kathryn M. Lemberg et al.   MOLECULAR CANCER THERAPEUTICS

N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders

(2017) Michael T. Nedelcovych et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

(2016) Rana Rais et al.   JOURNAL OF MEDICINAL CHEMISTRY

Searching for Improved Photoreleasing Abilities of Organic Molecules

(2015) Tomáš Šolomek et al.   ACCOUNTS OF CHEMICAL RESEARCH

Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy

(2012) Petr Klán et al.   CHEMICAL REVIEWS

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE