A role for the cystathionine-β-synthase /H2S axis in astrocyte dysfunction in the aging brain

Elevated plasma sulfides are associated with cognitive dysfunction and brain atrophy in human Alzheimer's disease and related dementias

(2023) Tyler H. Reekes et al.   Redox Biology

Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome

(2022) Theodora Panagaki et al.   Redox Biology

Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

(2021) Daniel Giovinazzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias

(2021) Elizabeth Disbrow et al.   Alzheimers & Dementia

Identification of region-specific astrocyte subtypes at single cell resolution

(2020) Mykhailo Y. Batiuk et al.   Nature Communications

Astrocyte mitochondria: Central players and potential therapeutic targets for neurodegenerative diseases and injury

(2020) J.L. Gollihue et al.   AGEING RESEARCH REVIEWS

Cystathionine beta synthase regulates mitochondrial dynamics and function in endothelial cells

(2020) Geeta Rao et al.   FASEB JOURNAL

Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity

(2020) Ferran Comas et al.   Redox Biology

Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2

(2020) Anindya Dey et al.   Science Advances

Microglia and astrocyte dysfunction in parkinson's disease

(2020) Tae-In Kam et al.   NEUROBIOLOGY OF DISEASE

Ionic signalling in astroglia beyond calcium

(2019) Alexei Verkhratsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

(2019) Amaia M Arranz et al.   LANCET NEUROLOGY

Single-cell transcriptomic profiling of the aging mouse brain

(2019) Methodios Ximerakis et al.   NATURE NEUROSCIENCE

Astrocytes: Role and Functions in Brain Pathologies

(2019) Rosalba Siracusa et al.   Frontiers in Pharmacology

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

(2019) Jasmina Zivanovic et al.   Cell Metabolism

Hydrogen sulfide signaling in mitochondria and disease

(2019) Brennah Murphy et al.   FASEB JOURNAL

Cystathionine β-synthase regulates mitochondrial morphogenesis in ovarian cancer

(2018) Prabir Kumar Chakraborty et al.   FASEB JOURNAL

Regulation of platelet activation and thrombus formation by reactive oxygen species

(2018) Jianlin Qiao et al.   Redox Biology

Astrocytes, Microglia, and Parkinson's Disease

(2018) Eun-Hye Joe et al.   Experimental Neurobiology

Unravelling and Exploiting Astrocyte Dysfunction in Huntington’s Disease

(2017) Baljit S. Khakh et al.   TRENDS IN NEUROSCIENCES

The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

(2017) Heather D.E. Booth et al.   TRENDS IN NEUROSCIENCES

Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration

(2016) Sounik Saha et al.   FASEB JOURNAL

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

S- Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics

(2016) Katalin Módis et al.   PHARMACOLOGICAL RESEARCH

Oxidative stress signaling to chromatin in health and disease

(2016) Sarah Kreuz et al.   Epigenomics

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke

(2013) Heng Zhao et al.   PLoS One

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S Signals Through Protein S-Sulfhydration

(2009) A. K. Mustafa et al.   Science Signaling