Bone-Adhesive Hydrogel for Effective Inhibition of M. tuberculosis and Osteoblast Regeneration

A Mechanically Reinforced Super Bone Glue Makes a Leap in Hard Tissue Strong Adhesion and Augmented Bone Regeneration

(2023) Shanshan Hu et al.   Advanced Science

MetaDOCK: A Combinatorial Molecular Docking Approach

(2023) Izaz Monir Kamal et al.   ACS Omega

Blue-ringed octopus-inspired microneedle patch for robust tissue surface adhesion and active injection drug delivery

(2023) Zhou Zhu et al.   Science Advances

L-Lysine-Modified pNIPAm-co-GMA Copolymer Hydrogel for pH- and Temperature-Responsive Drug Delivery and Fluorescence Imaging Applications

(2023) Madhappan Santhamoorthy et al.   Gels

Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant

(2023) Souvik Sarkar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of [1,2,4]triazolo[4,3-b]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study

(2023) Jung-Hoon Kim et al.   Scientific Reports

Self-Assembled Inhalable Immunomodulatory Silk Fibroin Nanocarriers for Enhanced Drug Loading and Intracellular Antibacterial Activity

(2022) Kartik Mitra et al.   ACS Biomaterials-Science & Engineering

Novel temperature/pH-responsive hydrogels based on succinoglycan/poly(N-isopropylacrylamide) with improved mechanical and swelling properties

(2022) Yiluo Hu et al.   EUROPEAN POLYMER JOURNAL

Tuberculosis Drug Discovery: Challenges and New Horizons

(2022) Guilherme F. S. Fernandes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of an antibiotics delivery system for topical treatment of the neglected tropical disease Buruli ulcer

(2022) Ana I. Mendes et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein

(2022) Hoonhee Seo et al.   PLOS BIOLOGY

Hydrogel microspheres for spatiotemporally controlled delivery of RNA and silencing gene expression within scaffold-free tissue engineered constructs

(2021) Alexandra McMillan et al.   Acta Biomaterialia

Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein

(2021) Chuancai Sun et al.   PLoS One

Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains

(2021) Akanksha Sharma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural, morphological and biological evaluations of cerium incorporated hydroxyapatite sol–gel coatings on Ti–6Al–4V for orthopaedic applications

(2021) B. Priyadarshini et al.   Journal of Materials Research and Technology-JMR&T

Immunomodulating polyorganophosphazene-arginine layered liposome antibiotic delivery vehicle against pulmonary tuberculosis

(2021) Sivaraj Mehnath et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Bone‐Adhesive Hydrogels Based on Dual Crosslinked Poly(2‐oxazoline)s

(2021) María J. Sánchez‐Fernández et al.   MACROMOLECULAR BIOSCIENCE

Fabrication of bone-targeting hyaluronic acid coupled alendronate-bioactive glass for osteosarcoma therapy

(2021) Sivaraj Mehnath et al.   MATERIALS CHEMISTRY AND PHYSICS

Targeted Theranostics for Tuberculosis: A Rifampicin-Loaded Aggregation-Induced Emission Carrier for Granulomas-Tracking and Anti-Infection

(2020) Yuhui Liao et al.   ACS Nano

Improvement in ADMET Prediction with Multitask Deep Featurization

(2020) Evan N. Feinberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mycobacterium culturing and drug resistance of osteoarticular tuberculosis in Xinjiang, China

(2020) Yeerzati Hajiaheman et al.   MEDICINE

ZIF-8-Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration

(2020) Yanhua Liu et al.   ACS Applied Materials & Interfaces

Chitosan-based particulate systems for drug and vaccine delivery in the treatment and prevention of neglected tropical diseases

(2020) Sevda Şenel et al.   Drug Delivery and Translational Research

Thiolated Thermoresponsive Polymer Scaffolds with Tunable Mucoadhesivity for Intestinal Applications

(2020) Ninad S. Kanetkar et al.   BIOMACROMOLECULES

Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial

(2019) Chandrasekaran Padmapriyadarsini et al.   BMJ Open

Poly(N-isopropylacrylamide)/polydopamine/clay nanocomposite hydrogels with stretchability, conductivity, and dual light- and thermo- responsive bending and adhesive properties

(2019) Xiang Di et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration

(2019) Anna M. McDermott et al.   Science Translational Medicine

Click chemistry synthesis, biological evaluation and docking study of some novel 2′-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents

(2019) Andrew N. Boshra et al.   BIOORGANIC CHEMISTRY

Lapazine loaded Alginate/Chitosan microparticles: Enhancement of anti-mycobacterium activity

(2019) Mariana M. Longuinho et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Design, synthesis and antibacterial properties of pyrimido[4,5- b ]indol-8-amine inhibitors of DNA gyrase

(2018) David H. McGarry et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Characterization of PNIPAAm-co-AAm hydrogels for modified release of bromelain

(2018) Fernanda Machado Croisfelt et al.   EUROPEAN POLYMER JOURNAL

Antimicrobial hydrogels: promising materials for medical application

(2018) Kerong Yang et al.   International Journal of Nanomedicine

Growth ofMycobacterium tuberculosisin vivo segregates with host macrophage metabolism and ontogeny

(2018) Lu Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New drugs and regimens for tuberculosis

(2018) Kwok-Chiu Chang et al.   RESPIROLOGY

Mutations inside rifampicin-resistance determining region of rpoB gene associated with rifampicin-resistance in Mycobacterium tuberculosis

(2018) Myo T. Zaw et al.   Journal of Infection and Public Health

Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis

(2018) Hamed Mosaei et al.   MOLECULAR CELL

Six vs Twelve Months of Anti Tubercular Therapy in Patients with Biopsy Proven Spinal Tuberculosis

(2018) Abhay M. Nene et al.   SPINE

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase

(2018) Giorgia Mori et al.   TUBERCULOSIS

PotentialNet for Molecular Property Prediction

(2018) Evan N. Feinberg et al.   ACS Central Science

Hyaluronic acid conjugation facilitates clearance of intracellular bacterial infections by streptomycin with neglectable nephrotoxicity

(2017) Yuanhao Qiu et al.   GLYCOBIOLOGY

Vitamin D Counteracts Mycobacterium tuberculosis-Induced Cathelicidin Downregulation in Dendritic Cells and Allows Th1 Differentiation and IFNγ Secretion

(2017) Anna K. O. Rode et al.   Frontiers in Immunology

A Flow Cytometry Method for Rapidly Assessing Mycobacterium tuberculosis Responses to Antibiotics with Different Modes of Action

(2016) Charlotte Louise Hendon-Dunn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

LCST Behavior of Symmetrical PNiPAm-b-PEtOx-b-PNiPAm Triblock Copolymers

(2016) Martin Sahn et al.   MACROMOLECULES

The co-transcriptome of uropathogenicEscherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions

(2015) Charalampos Harris Mavromatis et al.   CELLULAR MICROBIOLOGY

Cysteine-Functional Polymers via Thiol-ene Conjugation

(2015) Matthias Kuhlmann et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Poly(N-isopropylacrylamide) Hydrogels Crosslinked by Small-Molecular Crosslinkers Through Click Chemistry

(2014) Jianquan Wang et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Thermoresponsive Injectable Hydrogels Cross-Linked by Native Chemical Ligation

(2014) Kristel W. M. Boere et al.   MACROMOLECULES

Role of N-vinyl-2-pyrrolidinone on the thermoresponsive behavior of PNIPAm hydrogel and its release kinetics using dye and vitamin-B12 as model drug

(2013) B. Maheswari et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

A versatile characterization of poly(N-isopropylacrylamide-co-N,N'-methylene-bis-acrylamide) hydrogels for composition, mechanical strength, and rheology

(2012) A. Chetty et al.   Express Polymer Letters

Filopodia and adhesion in cancer cell motility

(2011) Antti Arjonen et al.   Cell Adhesion & Migration

Cysteine-Containing Polyisocyanides as Versatile Nanoplatforms for Chromophoric and Bioscaffolding

(2010) Stéphane Le Gac et al.   CHEMISTRY-A EUROPEAN JOURNAL