Dimethyl fumarate treatment in relapsing remitting MS changes the inflammatory CSF protein profile by a prominent decrease in T-helper 1 immunity

Identification of early neurodegenerative pathways in progressive multiple sclerosis

(2022) Max Kaufmann et al.   NATURE NEUROSCIENCE

High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis

(2022) Martin Diebold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological effects of dimethyl fumarate treatment in blood and CSF of patients with primary progressive MS

(2021) J. Talbot et al.   JOURNAL OF NEUROIMMUNOLOGY

Inflammation-related plasma and CSF biomarkers for multiple sclerosis

(2020) Jesse Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current and emerging disease‐modulatory therapies and treatment targets for multiple sclerosis

(2020) F. Piehl   JOURNAL OF INTERNAL MEDICINE

Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo

(2019) Brian Chiou et al.   Journal of Neuroinflammation

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis

(2019) Edoardo Galli et al.   NATURE MEDICINE

Dimethyl Fumarate: A Review in Relapsing-Remitting MS

(2019) Hannah A. Blair   DRUGS

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

(2018) Alan J Thompson et al.   LANCET NEUROLOGY

Dimethyl fumarate treatment in multiple sclerosis: Recent advances in clinical and immunological studies

(2018) Gwendoline Montes Diaz et al.   AUTOIMMUNITY REVIEWS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Dimethyl Fumarate Selectively Reduces Memory T Cells and Shifts the Balance between Th1/Th17 and Th2 in Multiple Sclerosis Patients

(2017) Qi Wu et al.   JOURNAL OF IMMUNOLOGY

Nrf2, cellular redox regulation, and neurologic implications

(2017) Eduardo E. Benarroch   NEUROLOGY

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

(2016) Melanie S. Brennan et al.   ANTIOXIDANTS & REDOX SIGNALING

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Dimethyl fumarate selectively reduces memory T cells in multiple sclerosis patients

(2015) Erin E Longbrake et al.   Multiple Sclerosis Journal

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

Dimethyl fumarate selectively reduces memory T cells in multiple sclerosis patients

(2015) Erin E Longbrake et al.   Multiple Sclerosis Journal

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE

(2014) Hui Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Semaphorins and plexins as therapeutic targets

(2014) Thomas Worzfeld et al.   NATURE REVIEWS DRUG DISCOVERY

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

(2014) Erika Assarsson et al.   PLoS One

The Role of Neurotrophins in Multiple Sclerosis—Pathological and Clinical Implications

(2012) Alicja Kalinowska-Lyszczarz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-  Therapy in Multiple Sclerosis

(2012) Y. Nakatsuji et al.   JOURNAL OF IMMUNOLOGY

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Roles of Sema4D-Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2009) T. Okuno et al.   JOURNAL OF IMMUNOLOGY

Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study

(2009) Eva Havrdova et al.   LANCET NEUROLOGY

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY