Expression Profiles of circRNAs and Identification of hsa_circ_0007608 and hsa_circ_0064656 as Potential Biomarkers for COPD-PH Patients

N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2

(2023) Haibo Xia et al.   CELL DEATH AND DIFFERENTIATION

Synergizing the enhanced RIME with fuzzy K-nearest neighbor for diagnose of pulmonary hypertension

(2023) Xiaoming Yu et al.   COMPUTERS IN BIOLOGY AND MEDICINE

The regulation of circRNA_kif26b on alveolar epithelial cell senescence via miR-346-3p is involved in microplastics-induced lung injuries

(2023) Hangjun Luo et al.   Science of The Total Environment

Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

(2023) Mariya M. Kucherenko et al.   Nature Communications

l-Arginine, as an essential amino acid, is a potential substitute for treating COPD via regulation of ROS/NLRP3/NF-κB signaling pathway

(2023) Chunhua Ma et al.   Cell and Bioscience

Interleukin-6 and pulmonary hypertension: from physiopathology to therapy

(2023) Wei-Jie Xu et al.   Frontiers in Immunology

Stem cell therapy in pulmonary hypertension: current practice and future opportunities

(2023) Ruixuan Zheng et al.   European Respiratory Review

Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of Tripterygium wilfordii against Pulmonary Artery Hypertension

(2022) Shifa Wang et al.   Evidence-based Complementary and Alternative Medicine

Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways

(2022) Ran-Ran Wang et al.   Frontiers in Pharmacology

Altered Cellular Immunity and Differentially Expressed Immune-Related Genes in Patients With Systemic Sclerosis–Associated Pulmonary Arterial Hypertension

(2022) Jianxin Tu et al.   Frontiers in Immunology

Potential mechanisms of Qili Qiangxin capsule to prevent pulmonary arterial hypertension based on network pharmacology analysis in a rat model

(2022) Xiao Han et al.   Annals of Translational Medicine

Integrated Bioinformatic Analysis Reveals TXNRD1 as a Novel Biomarker and Potential Therapeutic Target in Idiopathic Pulmonary Arterial Hypertension

(2022) Wenchao Lin et al.   Frontiers in Medicine

Integrated bioinformatics analysis reveals marker genes and immune infiltration for pulmonary arterial hypertension

(2022) Shengxin Tang et al.   Scientific Reports

Novel p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Hypoxia-Induced Pulmonary Arterial Hypertension in Rats

(2022) Grazielle Fernandes Silva et al.   Pharmaceuticals

Mice lacking 1,4,5-triphosphate inositol type III receptor demonstrate inhibition of hypoxic pulmonary hypertension

(2022) Xinyue Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis

(2022) Rui-Qi Wei et al.   Canadian Respiratory Journal

The involvement of copper, circular RNAs, and inflammatory cytokines in chronic respiratory disease

(2022) Zehao Chen et al.   CHEMOSPHERE

An Overview of the Advances in Research on the Molecular Function and Specific Role of Circular RNA in Cardiovascular Diseases

(2022) Lianli Yin et al.   Biomed Research International

Comprehensive analysis and validation of novel immune and vascular remodeling related genes signature associated with drug interactions in pulmonary arterial hypertension

(2022) Jie Wang et al.   Frontiers in Genetics

Comprehensive analysis of the expression of N6-methyladenosine RNA methylation regulators in pulmonary artery hypertension

(2022) Hao Zheng et al.   Frontiers in Genetics

The emerging roles and mechanisms of exosomal non-coding RNAs in the mutual regulation between adipose tissue and other related tissues in obesity and metabolic diseases

(2022) Shifeng Pan et al.   Frontiers in Endocrinology

Transcriptome sequencing of hepatocellular carcinoma uncovers multiple types of dysregulated ncRNAs

(2022) Li Zhang et al.   Frontiers in Oncology

Synonymous mutations in TLR2 and TLR9 genes decrease COPD susceptibility in the Chinese Han population

(2022) X. Ding et al.   Pulmonology

Vascular pathobiology of pulmonary hypertension

(2022) Eunate Gallardo-Vara et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Pathophysiology and Pathogenic Mechanisms of Pulmonary Hypertension: Role of Membrane Receptors, Ion Channels and Ca2+ Signaling

(2022) Angela Balistrieri et al.   PHYSIOLOGICAL REVIEWS

PPARγ increases HUWE1 to attenuate NF-κB/p65 and sickle cell disease with pulmonary hypertension

(2021) Andrew J. Jang et al.   Blood Advances

Pulmonary hypertension in patients with chronic obstructive lung disease: results from COMPERA

(2021) Carmine Dario Vizza et al.   CHEST

Association Between Initial Treatment Strategy and Long-term Survival in Pulmonary Arterial Hypertension

(2021) Athénaïs Boucly et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TNF-α induces endothelial–mesenchymal transition promoting stromal development of pancreatic adenocarcinoma

(2021) Marjorie Adjuto-Saccone et al.   Cell Death & Disease

Updated Perspectives on Pulmonary Hypertension in COPD

(2020) Isabel Blanco et al.   International Journal of Chronic Obstructive Pulmonary Disease

hsa_circNFXL1_009 modulates apoptosis, proliferation, migration, and potassium channel activation in pulmonary hypertension

(2020) Xin Jin et al.   Molecular Therapy-Nucleic Acids

Regulation of circular RNAs act as ceRNA in a hypoxic pulmonary hypertension rat model

(2020) Shuang-Lan Xu et al.   GENOMICS

MiR-204 regulates type 1 IP3R to control vascular smooth muscle cell contractility and blood pressure

(2019) Mohanad Gabani et al.   CELL CALCIUM

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension

(2019) Rahul Kumar et al.   CARDIOVASCULAR RESEARCH

Novel insight into the genetic basis of high-altitude pulmonary hypertension in Kyrgyz highlanders

(2018) Arya Iranmehr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes

(2015) Steven C. Pugliese et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Matrix metalloproteinases and their inhibitors in pulmonary hypertension

(2012) Prakash Chelladurai et al.   EUROPEAN RESPIRATORY JOURNAL

IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner

(2012) Monika Maleszewska et al.   IMMUNOBIOLOGY