Extremely low frequency alternating magnetic field-triggered and MRI-traced drug delivery by optimized magnetic zeolitic imidazolate framework-90 nanoparticles

An extremely low frequency alternating magnetic field (ELF-AMF) was demonstrated to be able to effectively trigger drug release from carefully engineered magnetic ZIF-90 nanoparticles. The embedded Fe3O4 nanoparticles or alternatively Gd2O3 nanoparticles serve as effective MRI tracers for potential visualization of drug delivery to ensure drug delivery accuracy.