Article
Chemistry, Multidisciplinary
Fu-Sheng He, Min Yang, Shengqing Ye, Jie Wu
Summary: The use of sodium dithionite and thiourea dioxide as sources of sulfonyl groups in recent synthetic reactions has become a research hotspot due to their alternative and complementary routes. These strategies offer mild conditions and broad substrate scopes with excellent functional group compatibility.
CHINESE CHEMICAL LETTERS
(2021)
Review
Chemistry, Organic
Gang Chen, Zhong Lian
Summary: Compounds containing sulfonyl-derived functional groups have garnered significant attention due to their numerous applications in life science, pharmaceuticals, and materials science. In recent years, multi-component sulfonylation reactions utilizing sulfur dioxide (SO2) insertion strategy have emerged as innovative and attractive approaches to access these compounds. The use of SO2 surrogates in the multi-component reactions (MCRs) has enhanced reaction flexibility and efficiency. Additionally, progress has been made in the development of asymmetric MCRs for the synthesis of valuable chiral sulfones. This review summarizes the advancements in MCRs involving SO2 surrogates from 2019 to 2022, while highlighting the potential and challenges in this field.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Michal Tryniszewski, Dariusz Basiak, Michal Barbasiewicz
Summary: Methanedisulfonyl fluoride can convert aromatic aldehydes into useful substrates and mimic the mechanism of Horner-Wadsworth-Emmons olefination. In the absence of base, electron-rich aldehydes can also undergo Knoevenagel condensation to yield unsaturated 1,1-disulfonyl fluorides. Additionally, elusive ethene-1,1-disulfonyl fluoride can be trapped with 4-(dimethylamino)pyridine to form a zwitterionic adduct as characterized by X-ray studies.
Article
Chemistry, Multidisciplinary
Deli Sun, Guobin Ma, Xinluo Zhao, Chuanhu Lei, Hegui Gong
Summary: An asymmetric Ni-catalyzed reductive cross-coupling of aryl/heteroaryl halides with racemic alpha -chlorosulfones is reported to synthesize enantioenriched sulfones. The reaction tolerates various functional groups under mild conditions, complementing current methods. The utility of this work was demonstrated through facile late-stage functionalization of commercial drugs.
Article
Engineering, Environmental
Qiyu Weng, Yingli Gong, Xiongwei Tian, Yuqun Zhuo, Shujuan Wang, Pengbo Hu, Tao Lyu
Summary: The research found that selenite in simulated slurry can be reduced by SO2 to form amorphous elemental selenium, while selenate remains unaffected. Increasing SO2 concentration in flue gas accelerates the reduction of selenite, and the reduction reaction is exothermic. Additionally, the oxidation effect of S2O82- competes with the reduction effect of SO2.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Organic
Yun-Hai Sun, Cheng-Jing Li, Ji-Ming Xi, Zhong-Lin Wei, Wei-Wei Liao
Summary: An electrochemical three-component transformation was developed for the synthesis of sulfonylated fused sultams using N-cyanamide alkene, Na2S2O5, and sulfonyl hydrazide. The reaction proceeds in an undivided electrolysis cell without a supporting electrolyte, utilizing cost-effective and easy-to-handle sodium metabisulfite as a SO2 surrogate. This sustainable and modular approach allows for the efficient construction of cyclic sulphonamides with a broad substrate scope and available reaction components.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Zili Zhang, Yao Lin, Jianwei Meng, Lei Wang, Qin Yao, Xiaohan Chen, Guodong Dai, Yi Zhao, Runlong Hao
Summary: This study investigated the effects of six types of fly ash on NO removal and characterized their micromorphology, elemental composition, and elemental oxidation states. The experimental results showed that high solubility is a prerequisite condition for fly ash to exhibit inhibitory effects on NO removal.
Article
Chemistry, Applied
Haiping Lv, Xiaochun He, Lin Shen, Xuemei Zhang, Zhong Lian
Summary: A palladium-catalyzed domino cyclization/direct aminosulfonylation of aryl iodides with amines via the insertion of SO2 (from SOgen) was developed, allowing the synthesis of a series of oxindole-based sulfonamides in moderate-to-good yields. A scale-up reaction and two synthetic applications demonstrated the robustness and practicality of this transformation.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Food Science & Technology
Alison Lacombe, Vivian C. H. Wu
Summary: This study examined the effect of post-treatment water rinsing on the antimicrobial efficacy of sequential treatments of NaOCl and ClO2 against various bacteria in frozen blueberries. The results showed that the combination treatment of NaOCl and ClO2 had a greater microbial reduction compared to the control, and post-treatment rinsing did not significantly impact the log reduction of bacteria. Post-treatment freezing doubled the antimicrobial effect in Salmonella and STEC.
Article
Engineering, Environmental
Haitao Yu, Jiejiao Liu, Qianwen Lin, Jun Liu, Siming Yu, Pinghua Sun, Jing Lin
Summary: This study successfully constructed a water-soluble dendronized chitooligosaccharide polymer with glutathione-responsive SO2-releasing property, which exhibited remarkable antibacterial activity against various bacteria and high biocompatibility.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Jinwook Lee, Seojin Jung, Hanjou Park, Jooyoun Kim
Summary: The study investigated the role of ZIF-8 crystals in charge trapping and capturing specific pollutants, demonstrating improved electrostatic filtration efficiency and enhanced SO2 capture ability when utilizing a corona charging process. The novel approach of associating particulate and gas capture capabilities with the charge trapping ability of ZIF-8 shows potential for multifunctional filtration applications.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Environmental Sciences
Yuchen Wang, Zhengshan Luo, Jihao Luo
Summary: This study proposes an innovative hybrid deep learning model for predicting the diffusion of toxic gas SO2, which demonstrates good performance with real data. The study also introduces time series generative adversarial networks for SO2 diffusion studies for the first time, and quantifies the contribution of driving factors and visualizes the maximum safe downwind distance to enhance the practicality of the research.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Organic
Qi Xue, Qing Sun, Ting-Ting Zhang, Yang Li, Jin-Heng Li
Summary: This practical and eco-friendly method allows controllable aerobic oxygenation of sulfides by electrochemical catalysis. The switchable preparation of sulfoxides and sulfones is effectively controlled by reaction time, utilizing both molecular oxygen and water as the oxygen source under catalyst and external oxidant-free conditions. The electrochemical protocol features a broad substrate scope, excellent site selectivity, and successful application in modifying sulfide-containing pharmaceuticals and their derivatives.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Applied
Bhargavi Rane, Alison Lacombe, Jiewen Guan, Lillian Lucero, David F. Bridges, Shyam Sablani, Juming Tang, Vivian C. H. Wu
Summary: This study found that fumigation with gaseous chlorine dioxide (ClO2) can effectively reduce mold contamination and toxin levels in almonds. At high concentrations, gaseous ClO2 demonstrated an 84.4% degradation efficiency of aflatoxin B1 (AFB1) and significantly reduced the number of Aspergillus flavus on almond kernels. The treated almonds also showed continued suppression of AFB1 even after one-month storage at low temperature, without any significant oxidative effects or color changes.
Article
Chemistry, Inorganic & Nuclear
Tayyebeh B. Champ, Jun H. Jang, Justin L. Lee, Guang Wu, Michael A. Reynolds, Mahdi M. Abu-Omar
Summary: A lignin-derived ligand, DHEG, was synthesized and used to prepare two iron and manganese complexes for the oxidation of chlorite to chlorine dioxide in aqueous solution. Green oxidant PAA was employed to form high-valent Fe and Mn intermediates, with Mn complex showing higher efficiency for chlorite oxidation. The rate of ClO2 decomposition with PAA/Mn-DHEG was found to be first order in PAA and increased significantly as pH increased.
INORGANIC CHEMISTRY
(2021)