The oomycete-specific BAG subfamily maintains protein homeostasis and promotes pathogenicity in an atypical HSP70-independent manner

Functional Diversity of Mammalian Small Heat Shock Proteins: A Review

(2023) Chaoguang Gu et al.   Cells

Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate

(2022) Daniel C. Carrettiero et al.   Nature Communications

A Phytophthora sojae CRN effector mediates phosphorylation and degradation of plant aquaporin proteins to suppress host immune signaling

(2021) Gan Ai et al.   PLoS Pathogens

Double-faced role of Bcl-2-associated athanogene 7 in plant–Phytophthora interaction

(2021) Yang Zhou et al.   JOURNAL OF EXPERIMENTAL BOTANY

PsGRASP, a Golgi Reassembly Stacking Protein in Phytophthora sojae, Is Required for Mycelial Growth, Stress Responses, and Plant Infection

(2021) Jierui Si et al.   Frontiers in Microbiology

A BAG's life: Every connection matters in cancer

(2020) Elena Mariotto et al.   PHARMACOLOGY & THERAPEUTICS

Protein homeostasis from the outside in

(2020) Brant M. Webster et al.   NATURE CELL BIOLOGY

Local unfolding of the HSP27 monomer regulates chaperone activity

(2019) T. Reid Alderson et al.   Nature Communications

Cytoprotective Co-chaperone BcBAG1 Is a Component for Fungal Development, Virulence, and Unfolded Protein Response (UPR) of Botrytis cinerea

(2019) Honghong Zhang et al.   Frontiers in Microbiology

CDD/SPARCLE: the conserved domain database in 2020

(2019) Shennan Lu et al.   NUCLEIC ACIDS RESEARCH

The Ancient Link between G-Protein-Coupled Receptors and C-Terminal Phospholipid Kinase Domains

(2018) D. Johan van den Hoogen et al.   mBio

Probing the Phylogenomics and Putative Pathogenicity Genes of Pythium insidiosum by Oomycete Genome Analyses

(2018) Thidarat Rujirawat et al.   Scientific Reports

A Bcl-2 Associated Athanogene (bagA) Modulates Sexual Development and Secondary Metabolism in the Filamentous Fungus Aspergillus nidulans

(2018) Sachin Jain et al.   Frontiers in Microbiology

An E3 Ubiquitin Ligase-BAG Protein Module Controls Plant Innate Immunity and Broad-Spectrum Disease Resistance

(2016) Quanyuan You et al.   Cell Host & Microbe

UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

(2016) Esben G. Poulsen et al.   CELL STRESS & CHAPERONES

Arabidopsis BAG1 Functions as a Cofactor in Hsc70-Mediated Proteasomal Degradation of Unimported Plastid Proteins

(2016) Dong Wook Lee et al.   Molecular Plant

Aspartyl protease mediated cleavage of AtBAG6 is necessary for autophagy and fungal resistance in plants

(2016) Yurong Li et al.   PLANT CELL

Breaking BAG: The Co-Chaperone BAG3 in Health and Disease

(2016) Christian Behl   TRENDS IN PHARMACOLOGICAL SCIENCES

A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis

(2015) Martin Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

Efficient disruption and replacement of an effector gene in the oomycetePhytophthora sojaeusing CRISPR/Cas9

(2015) Yufeng Fang et al.   MOLECULAR PLANT PATHOLOGY

Small heat shock proteins: big folding machines

(2014) Geneviève Morrow et al.   CELL STRESS & CHAPERONES

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

(2014) Lam-Tung Nguyen et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Top 10 oomycete pathogens in molecular plant pathology

(2014) Sophien Kamoun et al.   MOLECULAR PLANT PATHOLOGY

PsVPS1, a Dynamin-Related Protein, Is Involved in Cyst Germination and Soybean Infection of Phytophthora sojae

(2013) Delong Li et al.   PLoS One

Design Principles of Protein Biosynthesis-Coupled Quality Control

(2012) Monica C. Rodrigo-Brenni et al.   DEVELOPMENTAL CELL

A Lysine-Rich Region within Fungal BAG Domain-Containing Proteins Mediates a Novel Association with Ribosomes

(2012) Jacob Verghese et al.   EUKARYOTIC CELL

Emerging fungal threats to animal, plant and ecosystem health

(2012) Matthew C. Fisher et al.   NATURE

A Domain-Centric Analysis of Oomycete Plant Pathogen Genomes Reveals Unique Protein Organization

(2010) M. F. Seidl et al.   PLANT PHYSIOLOGY

AtBAG7, an Arabidopsis Bcl-2-associated athanogene, resides in the endoplasmic reticulum and is involved in the unfolded protein response

(2010) B. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

The BAG proteins: a ubiquitous family of chaperone regulators

(2008) M. Kabbage et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Horizontal gene transfer in eukaryotic evolution

(2008) Patrick J. Keeling et al.   NATURE REVIEWS GENETICS

Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2

(2008) Zhen Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE