Article
Biochemistry & Molecular Biology
Xilin Shen, Bingbing Wu, Wei Jiang, Yu Li, Yuping Zhang, Kun Zhao, Nanfang Nie, Lin Gong, Yixiao Liu, Xiaohui Zou, Jian Liu, Jingfen Jin, HongWei Ouyang
Summary: This study quantitatively measured the aging blood transcriptome and identified age-related genes. It revealed the characteristics of linear and non-linear dimensions of aging and evaluated the rejuvenation effect of molecules using an aging clock.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)
Article
Surgery
Mauricio de Maio
Summary: The MD Codes system is a universal symbolic language for reducing variability in injection technique to focus on both lessening unfavorable facial attributes and enhancing positive ones, ultimately improving patient satisfaction with treatment outcomes.
AESTHETIC PLASTIC SURGERY
(2021)
Review
Cell Biology
Bohan Zhang, Alexandre Trapp, Csaba Kerepesi, Vadim N. Gladyshev
Summary: There are interventions proposed to reverse aging rather than just slow it down, but the criteria for achieving rejuvenation are still controversial. A key prerequisite for a rejuvenation intervention is a significant reduction in biological age, which can be assessed by biomarkers such as epigenetic clocks.
Review
Cell Biology
Siamak Tabibzadeh
Summary: Pluripotency and senescence represent two extremes of cell life, but they are closely linked and can be generated together in different contexts. Senescence can promote the generation of pluripotency, while pluripotency can induce senescence. Precise control of senescence is necessary to harness the full benefits of pluripotency during tissue regeneration or rejuvenation.
AGEING RESEARCH REVIEWS
(2022)
Article
Dermatology
Mauricio de Maio, Elian Elisabeth Anne Brenninkmeijer, Iman Nurlin, Ligia Colucci, Tania Sanchez
Summary: Implementing the MD Codes for facial aesthetic treatment can improve facial emotional attributes, enhance social attributes, and overall well-being with natural-looking results.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Clinical Neurology
Christina Hennen, Seda Demir, Haidar Salimi Dafsari, Gilbert Wunderlich, Boris Boell, Christoph Hueser, Michael Thomas Barbe, Gereon Rudolf Fink, Maria Adele Rueger
Summary: Although BoNT/A is recommended for severe neurological diseases, its intragastric injection for weight reduction in obesity has not been determined. However, cases of botulism after intragastric BoNT/A injection have been reported, highlighting the risks of off-label use. International guidelines are needed to define indications and safe dosing schemes.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Cell Biology
Patrick T. Paine, Ada Nguyen, Alejandro Ocampo
Summary: Partial cellular reprogramming is a biological process that can modify cell age and has the potential to improve or restore various age-related traits. While it offers therapeutic benefits, there are also limitations and areas for future development in this field.
Article
Construction & Building Technology
Haisen Chen, Jun Xie, Shaopeng Wu, Chao Yang, Bo Gao, Dong Yang, Junlin Chen
Summary: The selective absorption of bitumen by BOF has been studied previously, but research on the selective absorption of bitumen by BOF at different aging stages is still lacking. This study aims to explore the selective absorption behavior of BOF towards bitumen components at different aging and rejuvenation stages, as well as the road performance of the bituminous mixtures at different stages. The results show that BOF and natural aggregates both exhibit selective absorption of bitumen, with BOF showing a more significant effect. The selective absorption of bitumen by aggregates exhibits a time-dependent effect, with the strongest selective absorption seen at the short-term aging stage. The ability of adhesion for bitumen decreases with aging, which is the key factor affecting the performance of bituminous mixtures.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Review
Food Science & Technology
Wei-Ting Wu, Ke-Vin Chang, Hsiang-Chi Chang, Lan-Rong Chen, Chen-Hsiang Kuan, Jung-Ting Kao, Ling-Ying Wei, Yunn-Jy Chen, Der-Sheng Han, Levent Ozcakar
Summary: This article discusses the application of high-resolution ultrasound in the evaluation of facial soft tissues, particularly in the localization prior to botulinum toxin injections. The article summarizes the findings of clinical studies on ultrasonographic imaging of facial muscles.
Article
Surgery
Andrea Lazzarotto, Massimo Robiony, Janos Cambiaso-Daniel, Riccardo Nocini, Alessandro Gualdi
Summary: The trend of aesthetic medical procedures, especially minimal invasive treatments using hyaluronic acid fillers, continues to grow globally. However, awareness of possible complications remains underrepresented. This article presents four key treatment areas for optimal overall facial rejuvenation.
FACIAL PLASTIC SURGERY
(2022)
Article
Cell Biology
Kyusik Ahn, Seung-Jae Lee, Inhee Mook-Jung
Summary: This article assesses the current state of knowledge on brain aging, with a focus on the roles of white matter and microglia, and suggests potential approaches for rejuvenating the aged brain.
AGEING RESEARCH REVIEWS
(2022)
Review
Microbiology
Francois Meurens, Frederic Carlin, Michel Federighi, Maria-Eleni Filippitzi, Matthieu Fournier, Philippe Fravalo, Jean-Pierre Ganiere, Lionel Grisot, Laurent Guillier, Didier Hilaire, Pauline Kooh, Sophie Le Bouquin-Leneveu, Caroline Le Marechal, Christelle Mazuet, Herve Morvan, Karine Petit, Jean-Pierre Vaillancourt, Cedric Woudstra
Summary: Clostridium botulinum is the main pathogen causing botulism in humans and animals. Different toxinotypes of the bacteria affect different species, with types A, B, and E being commonly found in humans, and types C, D, C/D, and D/C mainly affecting birds and cattle. However, the knowledge about these less common toxinotypes and their impact on animal and human health is limited. This review presents the current understanding of toxinotypes C, D, C/D, and D/C in cattle and poultry, including their epidemiological cycles and zoonotic potential.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Construction & Building Technology
Meng Guo, Meichen Liang, Anand Sreeram, Amit Bhasin, Daisong Luo
Summary: This study investigated the rejuvenation effect of reclaimed asphalt pavement binder and the impact of modification processes on asphalt binders. Results showed that the addition of rejuvenators reduced the complex modulus of asphalt binders, but further research is needed to fully understand the rejuvenation mechanisms.
INTERNATIONAL JOURNAL OF PAVEMENT ENGINEERING
(2022)
Article
Construction & Building Technology
Jianmin Ma, Yue Deng, Daquan Sun, Simon A. M. Hesp
Summary: The use of rejuvenators can help restore the performance of aged asphalt, but as time goes on, the performance of the rejuvenated mixture decreases significantly.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Review
Engineering, Biomedical
Robert S. Rosen, Martin L. Yarmush
Summary: The process of aging poses risks to health and functionality and has been the subject of investigation for potential therapeutics. However, identifying impactful treatments has been challenging due to limited experimental validation and study design. This review explores the biological mechanisms of aging, discusses promising therapeutic strategies, and proposes a unified approach for evaluating and vetting current and future treatments.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING
(2023)
Review
Dermatology
Greg J. Goodman, Steven Liew, Peter Callan, Sarah Hart
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2020)
Article
Dermatology
Greg J. Goodman, Steven Liew, Peter Callan, Sarah Hart, Naveen Somia, John Sullivan, Izolda Heydenrych
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2020)
Review
Dermatology
John R. Sullivan, Marius Rademaker, Greg Goodman, Philip Bekhor, Firas Al-Niaimi
Summary: The COVID-19 pandemic has disrupted medical practices, leading to a need for reassessment of infection control protocols for dermatologic laser and energy-based device treatments. Adherence to high standards of skin preparation, device disinfection, plume and aerosol management, and appropriate PPE can help mitigate inherent treatment risks, particularly in aerosol-generating procedures.
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2021)
Review
Critical Care Medicine
Patrick D. Mahar, Anneliese B. Spinks, Heather Cleland, Philip Bekhor, Jill S. Waibel, Cheng Lo, Gregory Goodman
Summary: Fractional ablative CO2 laser treatment for burn scars shows an average VSS improvement of 29% across 282 patients, although treatment regimens and outcomes vary widely. Further exploration is encouraged to understand and optimize this therapeutic tool.
JOURNAL OF BURN CARE & RESEARCH
(2021)
Letter
Surgery
Greg J. Goodman, Mark R. Magnusson, Peter Callan, Stefania Roberts, Sarah Hart, Cara B. McDonald, Steven Liew, Cath Porter, Niamh Corduff, Michael Clague
AESTHETIC SURGERY JOURNAL
(2021)
Article
Surgery
Greg J. Goodman, Mark R. Magnusson, Peter Callan, Stefania Roberts, Sarah Hart, Frank Lin, Eqram Rahman, Cara B. McDonald, Steven Liew, Cath Porter, Niamh Corduff, Michael Clague
Summary: Based on available literature, aspiration technique does not offer a reliable safety measure for filler injections, and it is safer to utilize injection techniques that avoid vascular injection rather than relying on aspiration.
AESTHETIC SURGERY JOURNAL
(2022)
Article
Dermatology
Greg J. Goodman, Lynda J. Spelman, Nicholas Lowe, Beta Bowen
Summary: ATX-101 showed safety and efficacy in reducing moderate/severe submental fat, with most patients experiencing mild/moderate adverse events during treatment, the highest pain scores were in the ATX-101 1.0% and 2.0% groups, and satisfaction with appearance and patient-assessed global improvement ratings increased in all ATX-101 treatment groups compared to placebo.
DERMATOLOGIC SURGERY
(2021)
Editorial Material
Surgery
Greg J. Goodman
AESTHETIC SURGERY JOURNAL
(2022)
Editorial Material
Surgery
Greg J. Goodman
AESTHETIC SURGERY JOURNAL
(2022)
Article
Surgery
Frank Lin, Greg J. Goodman, Mark Magnusson, Peter Callan, Stefania Roberts, Sarah Hart, Eqram Rahman, Cara B. McDonald, Steven Liew, Cath Porter, Niamh Corduff, Michael Clague
Summary: This study visualized and measured the movement of the needle tip during aspiration and injection of hyaluronic acid filler in real time. It found that aspiration causes retrograde movement of the needle tip, while injection causes anterograde movement. Double-handed aspiration and greater experience reduce needle tip movement. The study suggests that it is not advisable to rely solely on aspiration to prevent intravascular injection.
AESTHETIC SURGERY JOURNAL
(2022)
Article
Surgery
Greg J. Goodman, Wilson W. S. Ho, Kao-Jung Chang, Yu-Fang Ling, An-Yi Sheu
Summary: This study assessed the safety and efficacy of CBL-514 in reducing abdominal subcutaneous fat volume and thickness. The results showed that higher doses of CBL-514 significantly reduced abdominal fat volume and thickness, and the treatment was safe and well-tolerated.
AESTHETIC SURGERY JOURNAL
(2022)
Article
Surgery
Greg J. Goodman, Cara B. McDonald, Adrian Lim, Catherine E. Porter, Anand K. Deva, Mark Magnusson, Anita Patel, Sarah Hart, Peter Callan, Alice Rudd, Stefania Roberts, Katy Wallace, Philip Bekhor, Michael Clague, Linda Williams, Niamh Corduff, Nina Wines, Firas Al-Niaimi, Sabrina G. Fabi, Howard M. Studniberg, Saxon Smith, Angelo Tsirbas, Sean Arendse, Antoinette Ciconte, Terence Poon
Summary: This study established a consensus panel to investigate the pathogenesis of delayed-onset tissue nodules (DTNs) due to hyaluronic acid (HA) injections. Consensus was reached on 16 out of 20 questions, forming the basis for a classification and treatment guide. The study suggests that DTNs are likely infection initiated with a variable immune response, and attention to practitioner and patient hygiene, as well as early systemic infection treatment, is important.
AESTHETIC SURGERY JOURNAL
(2023)
Editorial Material
Surgery
Greg J. Goodman
AESTHETIC SURGERY JOURNAL
(2023)
Article
Dermatology
Greg J. Goodman, Katherine Armour, David Ong, Tanongkiet Tienthavorn, Yan Wu, Pei-Chun Chen, Elias Tam, Amanda Ong, Gina Messiha, Tara Telfer, Luiz E. T. Avelar
Summary: Skin glow is an important indicator of skin quality, but it has not been well-defined and quantified.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
