EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance
出版年份 2023 全文链接
标题
EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in β-cells compensating for obesity and insulin resistance
作者
关键词
-
出版物
Islets
Volume 15, Issue 1, Pages -
出版商
Informa UK Limited
发表日期
2023-07-07
DOI
10.1080/19382014.2023.2223327
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion
- (2021) Harpreet K. Sandhu et al. Pharmacology Research & Perspectives
- Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets
- (2020) Juliane Röthe et al. BIOLOGICAL PROCEDURES ONLINE
- Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells
- (2019) Trillian Gregg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance
- (2019) Pei-Chi Chan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
- (2018) Daniel J. Drucker Cell Metabolism
- The Many Faces of Rap1 GTPase
- (2018) Anna Jaśkiewicz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cellular signaling pathways regulating β‑cell proliferation as a promising therapeutic target in the treatment of diabetes (Review)
- (2018) Wen‑Juan Jiang et al. Experimental and Therapeutic Medicine
- Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons
- (2018) Xinjian Zhang et al. NEUROCHEMISTRY INTERNATIONAL
- Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling
- (2017) Bethany A. Carboneau et al. Journal of Cell Communication and Signaling
- Opposing effects of prostaglandin E 2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation
- (2017) Bethany A. Carboneau et al. Molecular Metabolism
- The PGE2EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice
- (2016) Ryan P. Ceddia et al. ENDOCRINOLOGY
- Prostaglandin E1inhibits endocytosis in the β-cell endocytosis
- (2016) Ying Zhao et al. JOURNAL OF ENDOCRINOLOGY
- Synergy Between GαzDeficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes
- (2016) Allison L. Brill et al. MOLECULAR ENDOCRINOLOGY
- Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction
- (2016) Hadi Khodabandehloo et al. Translational Research
- Glucagon-Like Peptide-1 Regulates Cholecystokinin Production in β-Cells to Protect From Apoptosis
- (2015) Amelia K. Linnemann et al. MOLECULAR ENDOCRINOLOGY
- A single-islet microplate assay to measure mouse and human islet insulin secretion
- (2015) Nathan A Truchan et al. Islets
- Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity
- (2015) Jeffrey Klarenbeek et al. PLoS One
- New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice
- (2014) George G. Holz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Role of Epac2A/Rap1 Signaling in Interplay Between Incretin and Sulfonylurea in Insulin Secretion
- (2014) Harumi Takahashi et al. DIABETES
- Group X Secretory Phospholipase A2Regulates Insulin Secretion through a Cyclooxygenase-2-dependent Mechanism
- (2014) Preetha Shridas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion
- (2013) M. E. Kimple et al. DIABETES
- Direct Measurements of Oscillatory Glycolysis in Pancreatic Islet β-Cells Using Novel Fluorescence Resonance Energy Transfer (FRET) Biosensors for Pyruvate Kinase M2 Activity
- (2013) Matthew J. Merrins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lipotoxicity disrupts incretin-regulated human β cell connectivity
- (2013) David J. Hodson et al. JOURNAL OF CLINICAL INVESTIGATION
- Deletion of GαZProtein Protects against Diet-induced Glucose Intolerance via Expansion of β-Cell Mass
- (2012) Michelle E. Kimple et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclooxygenase-2, Not Microsomal Prostaglandin E Synthase-1, Is the Mechanism for Interleukin-1β-induced Prostaglandin E2Production and Inhibition of Insulin Secretion in Pancreatic Islets
- (2012) Susan Parazzoli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Calcium Channels and Exocytosis in Mouse Adrenal Chromaffin Cells by Prostaglandin EP3 Receptors
- (2011) M. L. Jewell et al. MOLECULAR PHARMACOLOGY
- cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells
- (2010) Olof Idevall-Hagren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rap1 Promotes Multiple Pancreatic Islet Cell Functions and Signals through Mammalian Target of Rapamycin Complex 1 to Enhance Proliferation
- (2010) Patrick Kelly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation
- (2010) Dawn Belt Davis et al. MOLECULAR ENDOCRINOLOGY
- Regulation of insulin secretion: a matter of phase control and amplitude modulation
- (2009) J. C. Henquin DIABETOLOGIA
- Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology
- (2009) T. McAvoy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started