Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo

(2023) Rebecca K. Davidson et al.   DIABETES

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

(2023) Juha Saarikettu et al.   FASEB BioAdvances

The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function

(2022) Rebecca K Davidson et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5

(2022) Shiwei Liang et al.   Frontiers in Oncology

Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction

(2022) Michael A. Nauck et al.   Cardiovascular Diabetology

PDX1-MODY: A rare missense mutation as a cause of monogenic diabetes

(2021) Gabriella de M. Abreu et al.   European Journal of Medical Genetics

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

(2020) Julia Ast et al.   Nature Communications

Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8+ T cell response in tumor

(2020) Yuan Wang et al.   Science Advances

Gene-Specific Actions of Transcriptional Coregulators Facilitate Physiological Plasticity: Evidence for a Physiological Coregulator Code

(2020) Michael R. Stallcup et al.   TRENDS IN BIOCHEMICAL SCIENCES

Evaluation of post-translational modifications in histone proteins: A review on histone modification defects in developmental and neurological disorders

(2020) Shahin Ramazi et al.   JOURNAL OF BIOSCIENCES

SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression

(2020) Chaoliang Diao et al.   Molecular Oncology

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

(2019) Xianming Wang et al.   Molecular Metabolism

The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function

(2019) Jason M. Spaeth et al.   DIABETES

SND1 acts as a novel gene transcription activator recognizing the conserved Motif domains of Smad promoters, inducing TGFβ1 response and breast cancer metastasis

(2017) L Yu et al.   ONCOGENE

An Overview of Chromatin-Regulating Proteins in Cells

(2016) Pingyu Zhang et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

SND1 Acts Downstream of TGF 1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis

(2015) L. Yu et al.   CANCER RESEARCH

Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes involved in TNFα response in human hepatoma cells

(2015) Enara Arretxe et al.   NUCLEIC ACIDS RESEARCH

Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells

(2015) Brian McKenna et al.   Cell Reports

SND1 Affects Proliferation of Hepatocellular Carcinoma Cell Line SMMC-7721 by Regulating IGFBP3 Expression

(2014) Jie Yin et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

Tudor-SN, a Novel Coactivator of Peroxisome Proliferator-activated Receptor γ Protein, Is Essential for Adipogenesis

(2014) Zhongchao Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Beta Cell Dysfunction and Insulin Resistance

(2013) Marlon E. Cerf   Frontiers in Endocrinology

Tudor domain proteins in development

(2012) J. W. Pek et al.   DEVELOPMENT

Research Resource: The Pdx1 Cistrome of Pancreatic Islets

(2012) Cynthia Khoo et al.   MOLECULAR ENDOCRINOLOGY

Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma

(2011) Byoung Kwon Yoo et al.   HEPATOLOGY

Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes

(2010) A. Villasenor et al.   Disease Models & Mechanisms

Association of SND1 protein to low density lipid droplets in liver steatosis

(2010) I. Garcia-Arcos et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Staphylococcal Nuclease Domain-Containing Protein 1 as a Potential Tissue Marker for Prostate Cancer

(2009) Hidetoshi Kuruma et al.   AMERICAN JOURNAL OF PATHOLOGY

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

(2009) Jennifer M. Oliver-Krasinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Neonatal diabetes mellitus with pancreatic agenesis in an infant with homozygous IPF-1 Pro63fsX60 mutation

(2009) Inas H Thomas et al.   PEDIATRIC DIABETES

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing

(2008) C.-L. Li et al.   NUCLEIC ACIDS RESEARCH