期刊
MYCOSES
卷 59, 期 4, 页码 234-240出版社
WILEY
DOI: 10.1111/myc.12453
关键词
Caries; adults; Basque Country; Candida; colonisation; yeast
资金
- Fundacion ONCE (Oportunidad al Talento)
- Consejeria de Educacion, Universidades de Investigacion [GIC12 210-IT-696-13]
- Departamento de Industria, Comercio y Turismo [S-PR12UN002, S-PE1 3UN121]
- Vasco-Eusko Jaurlaritza, Fondo de Investigacion Sanitaria [FIS PI11/00203, UPV/EHU (UFI 11/25)]
Candida albicans is one of the most frequent pathogens of the oral cavity, as a major cause of opportunistic disease. Moreover, Candida could be a cofactor of common oral diseases, such as dental caries. The aim of this study was to analyse the oral yeast colonisation in adults with dental caries and to evaluate its relationship with this clinical entity. We studied 190 patients distributed into controls (58 patients) and patients with caries (132 patients). Oral samples were collected by oral rinse and cultured in a chromogenic agar. C. albicans was the most prevalent species isolated from oral specimens in both groups. Patients with caries had a greater Candida colonisation (74 patients, 56.1%), than persons without caries (18 patients, 31%, P < 0.01). Patients with caries were significantly more colonised by non-C. albicans species than individuals without caries (P = 0.006). Moreover, the diversity of Candida species was richer in patients suffering from caries. The odds ratio of the colonisation of patients with caries was 3.144 (95% CI 1.525-5.478). There is a significant clinical correlation between dental caries and oral Candida colonisation in adults.
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