Applying Proteomics in metabolic dysfunction-associated steatotic liver disease: From Mechanism to Biomarkers

A review of the current state of single-cell proteomics and future perspective

(2023) Rushdy Ahmad et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Single-Cell Proteomics with Spatial Attributes: Tools and Techniques

(2023) Vartika Lohani et al.   ACS Omega

A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

(2023) Olivier Govaere et al.   Nature Metabolism

Deep Visual Proteomics defines single-cell identity and heterogeneity

(2022) Andreas Mund et al.   NATURE BIOTECHNOLOGY

Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis

(2022) Giulia Angelini et al.   GUT

Unbiased spatial proteomics with single-cell resolution in tissues

(2022) Andreas Mund et al.   MOLECULAR CELL

Targeted proteomics on its way to discovery

(2022) Marta L. Mendes et al.   PROTEOMICS

Spatial proteomics in three-dimensional intact specimens

(2022) Harsharan Singh Bhatia et al.   CELL

Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology

(2022) Christoph B. Messner et al.   PROTEOMICS

Spatially resolved proteomics via tissue expansion

(2022) Lu Li et al.   Nature Communications

A droplet-based microfluidic flow cytometry enabling absolute quantification of single-cell proteins leveraging constriction channel

(2021) Hongyu Yang et al.   Microfluidics and Nanofluidics

Sex-dependent dynamics of metabolism in primary mouse hepatocytes

(2021) Luise Hochmuth et al.   ARCHIVES OF TOXICOLOGY

Label-free quantitative proteomic analysis of serum extracellular vesicles differentiating patients of alcoholic and nonalcoholic fatty liver diseases

(2021) Huu-Quang Nguyen et al.   Journal of Proteomics

Multi-omics profiling: the way towards precision medicine in metabolic diseases

(2021) Cheng Hu et al.   Journal of Molecular Cell Biology

DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing

(2021) Yufeng Li et al.   Cell Metabolism

Mass spectrometry‐based targeted proteomics for analysis of protein mutations

(2021) Tai‐Tu Lin et al.   MASS SPECTROMETRY REVIEWS

High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells

(2021) Ke-Yue Ma et al.   NATURE IMMUNOLOGY

Extracellular vesicles as a new hope for diagnosis and therapeutic intervention for hepatocellular carcinoma

(2021) Natthaphong Nimitrungtawee et al.   Cancer Medicine

Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis

(2021) Marina Serrano-Maciá et al.   Molecular Metabolism

S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development

(2020) Cyril Sobolewski et al.   GUT

Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis

(2020) Qiongming Liu et al.   JOURNAL OF HEPATOLOGY

Defining the carrier proteome limit for single-cell proteomics

(2020) Tommy K. Cheung et al.   NATURE METHODS

Spatial proteomics: a powerful discovery tool for cell biology

(2019) Emma Lundberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease

(2019) Lili Niu et al.   Molecular Systems Biology

Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate

(2019) Carmen G. Palii et al.   Cell Stem Cell

Integrin β1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH

(2019) Qianqian Guo et al.   JOURNAL OF HEPATOLOGY

Single-cell immune landscape of human atherosclerotic plaques

(2019) Dawn M. Fernandez et al.   NATURE MEDICINE

Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome

(2019) Birgit Knebel et al.   Frontiers in Cell and Developmental Biology

Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease

(2018) Yichao Zhao et al.   HEPATOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis

(2018) Natalie Krahmer et al.   DEVELOPMENTAL CELL

Single-cell proteomics

(2018) Allison Doerr   NATURE METHODS

Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi

(2018) Xuelian Xiong et al.   Molecular Metabolism

Recent progress in mass spectrometry proteomics for biomedical research

(2017) Xu Li et al.   Science China-Life Sciences

Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes

(2016) Petra Hirsova et al.   GASTROENTEROLOGY

Extracellular vesicles in liver pathobiology: Small particles with big impact

(2016) Petra Hirsova et al.   HEPATOLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Molecular classification of fatty liver by high-throughput profiling of protein post-translational modifications

(2016) Yasuyo Urasaki et al.   JOURNAL OF PATHOLOGY

Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes

(2015) Samar H. Ibrahim et al.   HEPATOLOGY

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

(2014) Davide Povero et al.   PLoS One

Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet

(2013) Anja Thomas et al.   Journal of Proteomics

Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy

(2010) Nagathihalli S Nagaraj et al.   Expert Review of Proteomics

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

(2009) Lauren N. Bell et al.   HEPATOLOGY

Differential expression of lumican and fatty acid binding protein-1: New insights into the histologic spectrum of nonalcoholic fatty liver disease

(2009) Michael Charlton et al.   HEPATOLOGY